Polymerized ionic liquids (PILs) exhibit complex ion transport dynamics that are central to advancing technology in energy storage and efficient energy conversion. In this work, we probe the behavior of charged polymer systems in the solvent\u2010free limit using a coarse\u2010grained Gaussian core model that explicitly incorporates long\u2010range electrostatic interactions. Our simulations span a wide range of chain lengths, from monomeric units to highly entangled polymers, revealing how both intrachain and interchain interactions govern key properties such as the radius of gyration, relaxation time, and diffusivity. Notably, charged polymers adhere to classical reptation scaling, indicating that electrostatic forces do not inhibit standard polymer melt scaling behavior. We quantify these effects by evaluating both the Onsager transport coefficients and the direct drift response under applied electric fields, thereby linking molecular trajectories to macroscopic ion conductivity.
\r\n\r\nOur findings show that as the chain length increases, the motion of polymerized ions becomes increasingly correlated, a trend that stabilizes ion conductivity despite decreasing diffusivity. This study demonstrates that the complex interplay between correlated motion and cooperative chain dynamics results in a relatively stable conductivity that increases over short chain length, plateaus in the transition regime, before decreasing in the fully entangled regime \u2014 contrary to idealized predictions based solely on diffusivity. By explicitly modeling the microscopic interactions and accounting for both hydrodynamic and electrostatic effects, we provide a physically grounded framework that captures the emergent behavior of these charged systems. In doing so, our work offers a robust platform for the rational design of next-generation PIL electrolytes, distinguishing itself from phenomenological models through clear, simulation-based insights.
" }, { "name": "Chang, Daniel Kwon", "degree": "Masters", "year": "2022", "title": "Nickel-Catalyzed Electroreductive Cross-Coupling Reactions of Anhydrides and Alkyl Halides", "advisor": "Reisman, Sarah E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05122022-031448609", "creators": [ { "name": { "family": "Chang", "given": "Daniel Kwon" }, "id": "Chang-Daniel-Kwon", "orcid": "0000-0003-4314-5886", "display_name": "Chang, Daniel Kwon" } ], "advisors": [ { "name": { "family": "Reisman", "given": "Sarah E." }, "id": "Reisman-S-E", "orcid": "0000-0001-8244-9300", "role": "advisor", "display_name": "Reisman, Sarah E." } ], "committee": [ { "name": { "family": "None", "given": "None" }, "display_name": "None, None" } ], "option_major": [ "chemistry" ], "doi": "10.7907/w0pr-fs28", "abstract": "The formation of new carbon\u2013carbon bonds is one of the most important transformations in organic chemistry due to its ability to build the backbone of organic molecules. Nickel-catalyzed reductive cross-coupling reactions have recently emerged as an efficient and powerful strategy for the creation of new carbon\u2013carbon bonds. Furthermore, electrochemistry can be harnessed to overcome some of the challenges encountered in many of the reductive cross-coupling reactions in the literature. Herein, we discuss the development of a new electroreductive nickel-catalyzed cross-coupling of anhydrides with unactivated alkyl bromides in collaboration with Amgen to produce large amounts of substituted cyclobutane products." }, { "name": "Glisman, Alec Gregory", "degree": "Masters", "year": "2022", "title": "Swimming in Potential Flow", "advisor": "Brady, John F.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12052021-002539806", "creators": [ { "name": { "family": "Glisman", "given": "Alec Gregory" }, "id": "Glisman-Alec-Gregory", "orcid": "0000-0001-9677-1958", "display_name": "Glisman, Alec Gregory" } ], "advisors": [ { "name": { "family": "Brady", "given": "John F." }, "id": "Brady-J-F", "orcid": "0000-0001-5817-9128", "role": "advisor", "display_name": "Brady, John F." } ], "committee": [ { "name": { "family": "Wang", "given": "Zhen-Gang" }, "id": "Wang-Zhen-Gang", "orcid": "0000-0002-3361-6114", "role": "chair", "display_name": "Wang, Zhen-Gang" }, { "name": { "family": "Colonius", "given": "Tim" }, "id": "Colonius-T", "orcid": "0000-0003-0326-3909", "role": "member", "display_name": "Colonius, Tim" }, { "name": { "family": "Hunt", "given": "Melany L." }, "id": "Hunt-M-L", "orcid": "0000-0001-5592-2334", "role": "member", "display_name": "Hunt, Melany L." }, { "name": { "family": "Brady", "given": "John F." }, "id": "Brady-J-F", "orcid": "0000-0001-5817-9128", "role": "member", "display_name": "Brady, John F." } ], "option_major": [ "chemeng" ], "doi": "10.7907/6xkb-rs66", "abstract": "Active bodies undergo self-propulsive motion in a fluid medium and span a broad range of length and time scales. This report focuses specifically on the motion at high Reynolds number, where inertial forces dominate the fluid dynamics. Many active systems spontaneously self-organize into visually striking structures: fish schooling, birds flocking, and bacterial colonies growing. Current models of emergent behavior in the inertial regime are mainly phenomenological and do not account for the fluid-mediated interactions between bodies. We seek to advance physical models of swimmers in high inertia environments. To this end, we explicitly model the hydrodynamics to discern what role the fluid medium plays in active group dynamics and whether it can reproduce the observed emergent phenomenon without the imposition of phenomenologically based interaction rules.
\r\n\r\nA minimal swimmer model consisting of three linked spheres is constructed, and we find self-propulsion without external forces or momentum transfer via vortex shedding. The inertial swimmer is also compared to an identical swimmer in the Stokes regime---where fluid inertia is neglected. The Stokes hydrodynamics are longer-ranged at leading order, and we demonstrate that the stronger hydrodynamic interactions lead to a greater center of mass translation after a period of articulation.
" }, { "name": "Yu, Jason Miao", "degree": "Masters", "year": "2019", "title": "Coupled Cluster Green's Functions for Periodic Systems: Ab-Inito Computation and Applications", "advisor": "Chan, Garnet K.", "url": "https://resolver.caltech.edu/CaltechTHESIS:07202019-210018604", "creators": [ { "name": { "family": "Yu", "given": "Jason Miao" }, "id": "Yu-Jason-Miao", "orcid": "0000-0002-2270-6798", "display_name": "Yu, Jason Miao" } ], "advisors": [ { "name": { "family": "Chan", "given": "Garnet K." }, "id": "Chan-Garnet-K-L", "orcid": "0000-0001-8009-6038", "role": "advisor", "display_name": "Chan, Garnet K." } ], "committee": [ { "name": { "family": "Stoltz", "given": "Brian M." }, "id": "Stoltz-B-M", "orcid": "0000-0001-9837-1528", "role": "chair", "display_name": "Stoltz, Brian M." }, { "name": { "family": "Chan", "given": "Garnet K." }, "id": "Chan-Garnet-K-L", "orcid": "0000-0001-8009-6038", "role": "member", "display_name": "Chan, Garnet K." } ], "option_major": [ "chemistry" ], "doi": "10.7907/0P9H-ZQ15", "abstract": "The Coupled Cluster Green\u2019s function method is expanded to periodic systems and preliminary results of the spectral function for diamond and graphene are shown. Future improvements and potential applications are discussed.
" }, { "name": "Chan, Katie Marie", "degree": "Masters", "year": "2018", "title": "Development of a Method for the Copper-Catalyzed Asymmetric Propargylation of Oxime Esters", "advisor": "Reisman, Sarah E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12272017-150231015", "creators": [ { "name": { "family": "Chan", "given": "Katie Marie" }, "id": "Chan-Katie-Marie", "orcid": "0000-0002-8220-9013", "display_name": "Chan, Katie Marie" } ], "advisors": [ { "name": { "family": "Reisman", "given": "Sarah E." }, "id": "Reisman-S-E", "role": "advisor", "display_name": "Reisman, Sarah E." } ], "committee": [ { "name": { "family": "None", "given": "None" }, "display_name": "None, None" } ], "option_major": [ "chemistry" ], "doi": "10.7907/Z9CR5RJC", "abstract": "Alkynes represent a significant motif in natural products and pharmaceutical drugs, and the wide variety of reactions they can undergo makes them a handy tool in total synthesis. They can be introduced readily in various manners, including via propargylations of ketones and aldehydes. However, one reaction that remains to be examined is the propargylation of oximes to give a propargyl hydroxylamine. Current enantioselective propargylations of oximes typically require a chiral auxiliary and/or rare metals such as palladium or indium. Having an enantioselective propargylation of oximes which could use an external ligand and more commonly available metals would facilitate use of the product in total synthesis, as well as potentially as an unnatural amino acid. Unusual amino acids including alkynes are desirable for their use in copper(I)-catalyzed azide-alkyne [3+2] dipolar cycloadditions, a common bioorthogonal reaction.
\r\n\r\nHerein, the development of a copper-catalyzed propargylation of oxime esters is described. Initial efforts to induce enantioselectivity using a zinc nucleophile-based system proved fruitless. Although some Lewis acids could raise the yield, the enantioselectivity remained very low. Therefore, new reaction conditions using a boronate nucleophile were investigated. The use of a copper catalyst with a diphosphine ligand gave the desired product in high enantioselectivity, albeit low yield.
" }, { "name": "Carsch, Kurtis Mickel", "degree": "Masters", "year": "2016", "title": "Bio-Inspired Homometallic and Heterometallic Clusters Relevant to the Oxygen-Evolving Complex of Photosystem II", "advisor": "Agapie, Theodor", "url": "https://resolver.caltech.edu/CaltechTHESIS:06022016-225404694", "creators": [ { "name": { "family": "Carsch", "given": "Kurtis Mickel" }, "id": "Carsch-Kurtis-Mickel", "display_name": "Carsch, Kurtis Mickel" } ], "advisors": [ { "name": { "family": "Agapie", "given": "Theodor" }, "id": "Agapie-T", "role": "advisor", "display_name": "Agapie, Theodor" } ], "committee": [ { "name": { "family": "None", "given": "None" }, "display_name": "None, None" } ], "option_major": [ "chemistry" ], "doi": "10.7907/Z9HH6H3V", "abstract": "The following two chapters delineate several endeavors to isolate and characterize functional models of the oxygen-evolving complex (OEC) of photosystem II. Understanding the electronic structure and the precise mechanism of the O\u2013O bond coupling step in the Kok cycle affords insight into this fundamental process and will guide the design of new earth-abundant catalysts to perform water oxidation under environmentally benign conditions. Nature performs this transformation by a heterometallic CaMn4O5 cluster arranged a tetra-metallic cubane bridged to a dangling manganese ion. Although a myriad of synthetic inorganic complexes are capable of water oxidation, these structures significantly underperform the OEC in terms of turnover number and turnover frequency. The objectives of this thesis are (i) to construct multimetallic clusters using the OEC as inspiration, (ii) to explore the reactivity of these clusters with oxygen-atom transfer reagents, and (iii) to identify intermediates responsible for oxygen-based chemistry.
\r\n\r\nIn Chapter 1, a series of pseudo-C3 symmetric tetra-manganese clusters with an interstitial \u00b54-oxygen was synthesized and characterized in several oxidation states. These clusters (of the general formula [LMn3(PhPz)3OMn][OTx]x; x = 1, 2) are supported by pyridine and alkoxide donors connected by a 1,3,5-triarylbenzene spacer. A \u00b54-oxygen coordinates all four metal centers that are also bridged by phenyl pyrazolate (PhPz) ligands. This arrangement furnishes a vacant coordination site at a site-differentiated (apical) metal center. Exposure of these clusters to oxygen-atom transfer reagents (OAT\u2019s) results in the intramolecular oxygenation of a C(sp2)\u2013H bond of the bridging phenyl pyrazolate. Similarly, using 2,6-difluorophenyl pyrazolate (F2ArPz) as the bridging ligand results in the oxygenation of the C\u2013F bond with concurrent F-atom transfer. This reactivity represents an unprecedented C\u2013F activation for molecular manganese complexes. All hydroxylated and fluorinated clusters were independently prepared to confirm the observed reactivity upon exposure to OAT\u2019s. The pathways responsible for arene activation \u2013 postulated to proceed through an iodosobenzene adduct and subsequent formation of a transient high-valent manganese-oxo motif \u2013 are discussed.
\r\n\r\nIn Chapter 2, a series of pseudo-C3 symmetric heterometallic Fe3Mn clusters of the general formula [LMn3(PhPz)3OMn][OTf]x (x = 1\u20133) was synthesized and characterized. Similar to their homometallic tetra-manganese and tetra-iron analogs (Chapter 1), these clusters contain four metal centers with a central bridging interstitial \u00b54-oxygen atom and bridging phenyl pyrazolate ligands. These clusters are further supported by pyridine and alkoxide donors, linked through a 1,3,5-triarylbenzene spacer. All complexes were characterized by zero-field 57Fe M\u00f6ssbauer spectroscopy to confirm the presence of a manganese metal center in the apical position, illustrating that these clusters are stable with respect to metal scrambling and/or decomposition. Treatment of these clusters with 1-(tert-butylsulfonyl)-2-iodosylbenzene (sPhIO) resulted in the oxygenation of the C(sp2)\u2013H bond of the proximal phenyl pyrazolate motif to afford [LMn3(PhPz)2(OArPz)OMn][OTf]x (x = 2, 3). During these studies, an unusual iodosobenzene adduct of [FeIII3MnII]3+ was isolated prior to C\u2013H activation. This adduct has been characterized both by single-crystal XRD and 1H-NMR spectroscopy. In order to gain insight into the C\u2013H bond oxygenation by this iodosobenzene adduct, preliminary computational studies are presented to discuss the viability of a transient manganese-oxo species responsible for arene hydroxylation.
\r\n" }, { "name": "Forte, Lila", "degree": "Masters", "year": "2016", "title": "Statistical Mechanical Framework for Predicting Cellular Response", "advisor": "Miller, Thomas F.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05272016-101847646", "creators": [ { "name": { "family": "Forte", "given": "Lila" }, "id": "Forte-Lila", "display_name": "Forte, Lila" } ], "advisors": [ { "name": { "family": "Miller", "given": "Thomas F." }, "id": "Miller-T-F", "role": "advisor", "display_name": "Miller, Thomas F." } ], "committee": [ { "name": { "family": "Miller", "given": "Thomas F." }, "id": "Miller-T-F", "role": "chair", "display_name": "Miller, Thomas F." } ], "option_major": [ "chemistry" ], "doi": "10.7907/Z9K07273", "abstract": "Developments in singe-cell analysis techniques allow simultaneous high-resolution measurements of cellular component copy number and variation within a cell population. These data provide a probability distribution for all possible states of the cell, as determined by the measured component copy number per cell. We have developed a highly-flexible, theoretical statistical mechanical framework that uses single-cell cellular component data to model the evolution of the probability distribution of those components in a cell in response to an external, physical or molecular, perturbation. This framework uses Bayesian inference to compare potential functional descriptions of how the perturbation couples to the system, and to determine the uncertainty in the parameter estimations given the data. We have applied this methodology to study the impact of changes in oxygen partial pressure on the behavior of glioblastoma multiform cancer cells. We find that oxygen concentration couples not only to individual proteins, but effects the underlying effective interactions between the studied proteins as well. The underlying effective interactions were found to couple linearly to the system, indicating a simple proportional change in the protein network across oxygen concentrations. This description of the system provides improved predictive capabilities for describing the probability distribution of the measured cellular components across a wider range of perturbation conditions than previous methods. Additionally, we apply this methodology to show how it could be used to predict effects in difficult experimental perturbation regimes, identifying undruggable regimes, as well as the result of knocking our individual or combinations of proteins or protein interactions." }, { "name": "Campbell, Taryn Langley", "degree": "Masters", "year": "2014", "title": "Studies Toward the Total Synthesis of Ritterazine B: The Investigation of Alkynylation Reactions for Use in the Synthesis of the Western Fragment", "advisor": "Reisman, Sarah", "url": "https://resolver.caltech.edu/CaltechTHESIS:05282014-120132545", "creators": [ { "name": { "family": "Campbell", "given": "Taryn Langley" }, "id": "Campbell-Taryn-Langley", "display_name": "Campbell, Taryn Langley" } ], "advisors": [ { "name": { "family": "Reisman", "given": "Sarah" }, "id": "Reisman-S-E", "role": "advisor", "display_name": "Reisman, Sarah" } ], "committee": [ { "name": { "family": "None", "given": "None" }, "display_name": "None, None" } ], "option_major": [ "chemistry" ], "doi": "10.7907/Z9P848WN", "abstract": "The ritterazine and cephalostatin natural products have biological activities and structures that are interesting to synthetic organic chemists. These products have been found to exhibit significant cytotoxicity against P388 murine leukemia cells, and therefore have the potential to be used as anticancer drugs. The ritterazines and cephalostatins are steroidal dimers joined by a central pyrazine ring. Given that the steroid halves are unsymmetrical and highly oxygenated, there are several challenges in synthesizing these compounds in an organic laboratory.
\r\n\r\nRitterazine B is the most potent derivative in the ritterazine family. Its biological activity is comparable to drugs that are being used to treat cancer today. For this reason, and the fact that there are no reported syntheses of ritterazine B to date, our lab set out to synthesize this natural product.
\r\n\r\nHerein, efforts toward the synthesis of the western fragment of ritterazine B are described. Two different routes are explored to access a common intermediate. An alkyne conjugate addition reaction was initially investigated due to the success of this key reaction in the synthesis of the eastern fragment. However, it has been found that a propargylation reaction has greater reactivity and yields, and has the potential to reduce the step count of the synthesis of the western fragment of ritterazine B.
\r\n" }, { "name": "Poulin-Kerstien, Katherine G.", "degree": "Masters", "year": "2008", "title": "Exploring Peptides as Template Scaffolds for Directed Olefin Metathesis Oligomerization", "advisor": "Tirrell, David A.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10312023-230530609", "creators": [ { "name": { "family": "Poulin-Kerstien", "given": "Katherine G." }, "id": "Poulin-Kerstien-Katherine-G", "display_name": "Poulin-Kerstien, Katherine G." } ], "advisors": [ { "name": { "family": "Tirrell", "given": "David A." }, "id": "Tirrell-D-A", "orcid": "0000-0003-3175-4596", "role": "advisor", "display_name": "Tirrell, David A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/226t-1843", "abstract": "[No Abstract]" }, { "name": "Kwan, Brian Joseph", "degree": "Masters", "year": "2005", "title": "Development of Sequential Olefin Cross Metathesis-Organocatalysis Methodology", "advisor": "Grubbs, Robert H.", "url": "https://resolver.caltech.edu/CaltechETD:etd-12202004-085725", "creators": [ { "name": { "family": "Kwan", "given": "Brian Joseph" }, "id": "Kwan-Brian-Joseph", "display_name": "Kwan, Brian Joseph" } ], "advisors": [ { "name": { "family": "Grubbs", "given": "Robert H." }, "id": "Grubbs-R-H", "role": "advisor", "display_name": "Grubbs, Robert H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/nv3a-nj90", "abstract": "No abstract." }, { "name": "Greene, Blake Bennet", "degree": "Masters", "year": "2004", "title": "Progress Toward the Total Synthesis of Salvadione-A and Related Diterpenoids", "advisor": "Stoltz, Brian M.", "url": "https://resolver.caltech.edu/CaltechETD:etd-06252004-084128", "creators": [ { "name": { "family": "Greene", "given": "Blake Bennet" }, "id": "Greene-Blake-Bennet", "display_name": "Greene, Blake Bennet" } ], "advisors": [ { "name": { "family": "Stoltz", "given": "Brian M." }, "id": "Stoltz-B-M", "role": "advisor", "display_name": "Stoltz, Brian M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/AAPZ-W246", "abstract": "Herein, we report our progress toward the total synthesis of salvadione-A, a structurally complex triterpenoid isolated from Salvia bucharica. We document a model system of our tandem Claisen/Cope/Diels-Alder strategy. Additionally, we describe the evolution of our strategy toward the synthesis of three structurally related diterpenoids-coulterone, cyclocoulterone, and komaroviquinone--from a cyclopropanation/Friedel-Crafts route to an anionic homo-Fries/intramolecular Barbier cyclization pathway.\r\n" }, { "name": "Luo, Wen-I", "degree": "Masters", "year": "2004", "title": "The Role of Fucose in Learning and Memory: the Identification of a Fucosylprotein, Synapsin I, in the Rat Brain and the Characterization of its Fucosylation", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04262013-154211086", "creators": [ { "name": { "family": "Luo", "given": "Wen-I" }, "id": "Luo-Wen-I", "display_name": "Luo, Wen-I" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/P7ZV-C811", "abstract": "Previous studies have shown that the glycoproteins containing the fucose moiety are involved in neuronal communication phenomena such as long-term potentiation and memory formation. These results imply that fucose containing glycoproteins might play an important role in learning and memory. To understand the role of fucose in neuronal communication, and the mechanisms by which fucose may be involved in information storage, the identification of fucosylproteins is essential. This report describes the identification and characterization of fucosylproteins in the brain, which will provide new insights into the role of the fucose involved molecular interactions.\r\n" }, { "name": "Zepernick, John F.", "degree": "Masters", "year": "2004", "title": "The Development of a Tandem Stille-Oxaelectrocyclization Reaction", "advisor": "Stoltz, Brian M.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10022012-135626882", "creators": [ { "name": { "family": "Zepernick", "given": "John F." }, "id": "Zepernick-John-F", "display_name": "Zepernick, John F." } ], "advisors": [ { "name": { "family": "Stoltz", "given": "Brian M." }, "id": "Stoltz-B-M", "role": "advisor", "display_name": "Stoltz, Brian M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/hc53-h270", "abstract": "No abstract." }, { "name": "Kelly, Melissa Ann", "degree": "Masters", "year": "2003", "title": "Some New Measurements of the Ground and v\u2082 = 1 States of HDO in the Region 200 \u2013 750 GHz", "advisor": "Blake, Geoffrey A.", "url": "https://resolver.caltech.edu/CaltechETD:etd-09162002-140330", "creators": [ { "name": { "family": "Kelly", "given": "Melissa Ann" }, "id": "Kelly-Melissa-Ann", "display_name": "Kelly, Melissa Ann" } ], "advisors": [ { "name": { "family": "Blake", "given": "Geoffrey A." }, "id": "Blake-G-A", "orcid": "0000-0003-0787-1610", "role": "advisor", "display_name": "Blake, Geoffrey A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/P33F-HD20", "abstract": "To facilitate measurements of HDO in molecular clouds, late-type stars and planetary atmospheres, several new lines of HDO were measured between 200 and 750 GHz. The measurements were done in a one-meter gas flow cell, with specially constructed diode multiplier sources and a liquid helium cooled InSb hot-electron bolometer. The lines measured were of very low intensity, thanks to their higher J and K values. Both a-type and b-type transitions were observed, in the vibrational ground state (000) and the first excited bending state (010). These lines were added to existing HDO spectral lines and fit using a least-squares regression of an Euler series Hamiltonian that has proven useful in the analysis of molecules with large vibrational amplitudes. The results were comparable in precision to existing analyses. The data will be beneficial to two upcoming remote sensing missions designed to investigate the far IR and microwave regions: SOFIA, an airborne observatory that will carry a 2.5m telescope and detectors into the upper atmosphere, and the Herschel space observatory, a cryogenically cooled 3.5m telescope that will operate at the L2 Lagrangian point some 1.5 million km from the Earth." }, { "name": "Spessard, Sarah Jane", "degree": "Masters", "year": "2003", "title": "Progress Toward the Total Synthesis of Garsubellin A and Structurally Related Phloroglucin Natural Products", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03142025-165919678", "creators": [ { "name": { "family": "Spessard", "given": "Sarah Jane" }, "id": "Spessard-Sarah-Jane", "display_name": "Spessard, Sarah Jane" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/1y2w-nn41", "abstract": "Progress toward the polyprenylated phloroglucin garsubellin A is presented. A\r\nhighly diastereoselective single-step cyclization reaction provides access to the\r\nbicyclo[3.3.1]nonane core of this natural product. Further elaboration to a more\r\nfunctionalized analog involves a sequential Claisen rearrangement/Grubbs olefin cross\r\nmetathesis strategy. Additionally, the feasibility of this strategy toward the preparation\r\nof the bis-quaternary carbon array found at the bridgehead positions of the phloroglucinol\r\nnatural products is demonstrated. Enantioselective strategies and model studies will also\r\nbe discussed." }, { "name": "Vadehra, Anand", "degree": "Masters", "year": "2003", "title": "DNA-Mediated Charge Transfer in Biological Contexts", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:02252025-185802207", "creators": [ { "name": { "family": "Vadehra", "given": "Anand" }, "id": "Vadehra-Anand", "display_name": "Vadehra, Anand" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/cqzg-1391", "abstract": "No abstract." }, { "name": "Chevillet, John Richard", "degree": "Masters", "year": "2002", "title": "Targeting Repeat Sequences with DNA-Binding Small Molecules", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:02022012-110126423", "creators": [ { "name": { "family": "Chevillet", "given": "John Richard" }, "id": "Chevillet-John-Richard", "display_name": "Chevillet, John Richard" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/3YF2-Y771", "abstract": "Recognition of repeat sequences in DNA would have applications in molecular biology. One of the most biologically interesting repeat sequences is the telomeric repeat which composes the ends of eukaryotic chromosomes; in vertebrates 5'-TTAGGG-3'. This sequence has been used as a model to study how DNA-binding polyamide molecules composed of pyrrole (Py) and imidazole (Im) residues bind to repeating sequences. DNase I footprinting shows that the polyamide-fluorophore conjugate IrnImImPy-\u03b3-PyPy((CH_2)_3N,N',N''trimethylbis hexamethylene)triamineOregonGreen488) PyPy-\u03b2-Me can bind the sequence 5'-AGGGTT-3' K_a = 1.8x10^8 M^(-1). \r\nQuantitative fluorescence titrations with varying patterns of telomeric repeat suggest that the molecule can tolerate another polyamide binding contiguously, but not two.\r\nTruncation of the tail of the conjugate to yield the molecule ImImImPy-\u03b3-Py Py((CH_2)_3N,N',N''trimethylbis (hexamethylene)triamine-OregonGreen488) PyPy-Me allows the compound to bind three contiguous sites, suggesting that steric polyamide-polyamide interactions control binding in this manner." }, { "name": "Johnson, Brian P.", "degree": "Masters", "year": "2002", "title": "Multifunctional Conjugates for Fluorescence and Magnetic Resonance Imaging", "advisor": "Meade, Thomas J.; Fraser, Scott E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:02262025-014025819", "creators": [ { "name": { "family": "Johnson", "given": "Brian P." }, "id": "Johnson-Brian-P", "orcid": "0000-0003-2565-4927", "display_name": "Johnson, Brian P." } ], "advisors": [ { "name": { "family": "Meade", "given": "Thomas J." }, "id": "Meade-T-J", "orcid": "0000-0001-6202-1155", "role": "advisor", "display_name": "Meade, Thomas J." }, { "name": { "family": "Fraser", "given": "Scott E." }, "id": "Fraser-S-E", "orcid": "0000-0002-5377-0223", "role": "advisor", "display_name": "Fraser, Scott E." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/mbc4-7j70", "abstract": "Computer-enhanced light microscopy imaging and magnetic resonance imaging (MRI) have emerged as leading techniques for in vivo monitoring of intact organisms. Employing the advantages of both techniques, a set of bifunctional, polymeric imaging agents is presented. A high-molecular weight, membrane impermeable scaffold such as dextran was chosen, so that the imaging agent would be trapped inside cells after injection. The molecular framework is covalently functionalized with multiple units of both gadolinium-diethylenetriaminepentaacetic acid and a fluorescent dye, such as 1,1 'dioctadecyl-3,3,3 ',3 '-tetramethylindocarbocyanine (DiI). The synthesis of this class of reporter probes is versatile, allowing for varying wavelengths of attached fluorophores and types of MRI agents to be used.
" }, { "name": "Main, Rebekah Mary", "degree": "Masters", "year": "2002", "title": "Studies Towards the Development of New Catalysts for Methane Conversion", "advisor": "Davis, Mark E.; Bercaw, John E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:02262025-185839420", "creators": [ { "name": { "family": "Main", "given": "Rebekah Mary" }, "id": "Main-Rebekah-Mary", "display_name": "Main, Rebekah Mary" } ], "advisors": [ { "name": { "family": "Davis", "given": "Mark E." }, "id": "Davis-M-E", "orcid": "0000-0001-8294-1477", "role": "advisor", "display_name": "Davis, Mark E." }, { "name": { "family": "Bercaw", "given": "John E." }, "id": "Bercaw-J-E", "role": "advisor", "display_name": "Bercaw, John E." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/xxcm-zd60", "abstract": "In efforts to develop new catalysts for the partial oxidation of methane to\r\nmethanol, studies were focused on developing supported aqueous phase (SAP) catalysts\r\nfor this chemistry. The work can be separated into two main projects. First, steps were\r\ntaken to prepare an organometallic SAP catalyst. A water-soluble sulfonated Pt diimine\r\nspecies has been prepared and supported on controlled-pore glass. The compound was\r\ncharacterized by solid state 13C CP-MAS NMR, and observations were made on the\r\ncompounds behavior. This work is carried out in collaboration with research into\r\nhomogeneous organometallic catalysts, and progress in this area is dependent on the\r\ndevelopment of successful homogeneous catalysts. The second project involves using\r\nplatinum/copper salt catalyst for the hydroxylation of alkanes, where dioxygen is the\r\nultimate oxidant. Several homogeneous reactions were carried out to investigate the\r\nreactivity of this catalyst system in solution. The catalysts were found to successfully\r\nhydroxylate sulfonated alkanes as well as ethane and methane, all with multiple platinum\r\nturnovers. Product characterizations were carried out using 1H NMR and GC/MS.\r\nEfforts were also begun to develop a SAP catalyst with the Pt/Cu system, modeled after\r\nthe SAP Pd/Cu Wacker oxidation catalyst." }, { "name": "Rosario-Ortiz, Fernando L.", "degree": "Masters", "year": "2002", "title": "Determination of the Relative Line Strengths of the A\u00b2A' \u2190 X\u00b2A\" and (200)\u2190(000) transitions of HO\u2082", "advisor": "Okumura, Mitchio; Sander, Stanley P.", "url": "https://resolver.caltech.edu/CaltechTHESIS:02022012-093757351", "creators": [ { "name": { "family": "Rosario-Ortiz", "given": "Fernando L." }, "id": "Rosario-Ortiz-Fernando-L", "display_name": "Rosario-Ortiz, Fernando L." } ], "advisors": [ { "name": { "family": "Okumura", "given": "Mitchio" }, "id": "Okumura-M", "orcid": "0000-0001-6874-1137", "role": "advisor", "display_name": "Okumura, Mitchio" }, { "name": { "family": "Sander", "given": "Stanley P." }, "id": "Sander-S-P", "role": "co-advisor", "display_name": "Sander, Stanley P." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/vh44-fh68", "abstract": "The hydroperoxyl radical (HO\u2082) has been one of the most studied triatomic radicals during the past few decades. Its roles in atmospheric chemistry through the HO\u2093 cycle as well as in processes such as combustion have made the study of this radical extremely important. In the past three decades the interest in the spectroscopy of this molecule has increased due in part by the need of detecting this radical in several different environments. Although its UV, mid- and far-IR transitions have been studied extensively, its near-IR transitions have not received much attention until recently. Among the transitions observed in this region, the A\u00b2A' \u2190 X\u00b2A\" first electronic transition and the (200)\u2190(000) first OH overtone transition are two of the most important. These bands offer many advantages for detection of HO\u2082 in kinetic experiments and possibly in situ. Due to the importance of these two bands, information on their intensity is needed to measure accurately the concentration of HO\u2082. An apparatus has been constructed to measure the line strengths of the A \u2190 X electronic transition at 1.43 \u00b5m and the (200)\u2190(000) first OH overtone transition at 1.51 \u00b5m by diode laser absorption spectroscopy." }, { "name": "Wilson, Rebecca Mary", "degree": "Masters", "year": "2002", "title": "Advances in Organic Catalysis: The Design of a Novel Asymmetric, Organocatalytic Intramolecular Diels Alder Reaction", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:08162013-153809045", "creators": [ { "name": { "family": "Wilson", "given": "Rebecca Mary" }, "id": "Wilson-Rebecca-Mary", "display_name": "Wilson, Rebecca Mary" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/emr9-4m89", "abstract": "[Introduction] The Diels-Aider reaction is one of the most powerful and widely exploited methods available for generating six-membered rings. Similarly, the intramolecular Diels-Alder (IMDA), in which the diene and dienophile reacting partners are tethered, has received a great deal of attention from synthetic chemists in recent years. The IMDA usually proceeds with excellent levels of regio- and stereocontrol to generate complex bicyclic systems with up to four contiguous stereocenters from relatively simple precursors. There have been a number of efforts to develop diastereoselective variants of the IMDA, but there are considerably fewer examples of catalytic, asymmetric IMDA variants." }, { "name": "Okada, Sheldon Yoshio", "degree": "Masters", "year": "2001", "title": "Synthesis and Biological Applications of Oligopeptide-Substituted Polynorbornenes", "advisor": "Grubbs, Robert H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:09172018-160205705", "creators": [ { "name": { "family": "Okada", "given": "Sheldon Yoshio" }, "id": "Okada-Sheldon-Yoshio", "display_name": "Okada, Sheldon Yoshio" } ], "advisors": [ { "name": { "family": "Grubbs", "given": "Robert H." }, "id": "Grubbs-R-H", "orcid": "0000-0002-0057-7817", "role": "advisor", "display_name": "Grubbs, Robert H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/76ch-0t79", "abstract": "Chapter 1
\r\n\r\nSynthetic fibronectin mimics have been constructed usmg functionalised norbomenyl polymers synthesized via ring-opening metathesis polymerization (ROMP). The ROMP reactions were catalyzed by newly developed ruthenium initiators. Prior to the synthesis of the fibronectin mimics, the polymerization reactions of a number of norbornene derivatives with pendent glycine or penta(ethylene oxide) (EO5) units were studied in order to select the derivatives with optimal characteristics: high yields, fast polymerization times, and narrow PDI's. For these initial studies Ru = CHPh(Cl2)(PCy3)2 (1) was used as the initiator. Based on these studies poly(5-norbomene-2-carboxyl) and poly(4-(Exo-3,5-dioxo-10-oxa-4-azatricyclo[5.2.1.0]dec-8-en-4-yl)-butyric acid) were chosen as the ideal backbones for a series of polymers functionalised with pendent arginine-glycine-aspartic acid (RGD) and serine-arginineasparagine (SRN) oligopeptides. The polymers containing a propyl spacer between the pendant group and the backbone were synthesized in an attempt to demonstrate that the presentation of the peptide units could be altered to closely mimic the natural presentation of these peptides in fibronection. Homopolymers and random copolymers containing various combinations of norbomene monomers with pendant EO5 (21 & 14), GRGD/RGD (24 & 29), and SRN (25 & 30) units were made. Copolymers with large RGD or SRN contents (> 10 mol %) could only be synthesised in high yields and narrow PDI's by using the newly developed ruthenium 2,3-dihydroimidazolylidene initiators Ru = CHPh(Cl)2(PCy3)(DHIMes) (2) or Ru = CH-CH = CH2(CH3)2(Cl)2 PCp3)(DIHMes) (3). In addition, the ROMP reactions of the norbornene monomers containing the propyl spacers also required the new initiator 2. Attempts to synthesize these polymers using ruthenium initiator 1 resulted in either low yields, bimodal molecular weight distributions, or a combination of both.
\r\n\r\nChapter 2
\r\n\r\nPolynorbomenes substituted with two different peptide sequences from the RGD containing integrin cell binding domain of fibronectin are potent inhibitors of human foreskin fibroblast cell adhesion to fibronectin-coated surfaces. Ring-opening metathesis polymerization (ROMP) using Ru = CHPh(Cl)2(PCy3)(DHIMes) (1) as an initiator produced polymers substituted with GRGDS and PHSRN peptide sequences. The inhibitory activity was quantified for these polymers and compared to the free peptides and GRGES containing controls. A homopolymer substituted with GRGDS peptides was significantly more active than the free GRGDS peptide (IC50 of 0.18 \u00b1 0.03 and 1.33 \u00b1 0.20 mM respectively), and the copolymer containing both GRGDS and PHSRN was the most potent inhibitor (IC50 of 0.04 \u00b1 0.01 mM). These results demonstrate that significant enhancements of observed biological activity can be obtained from polymeric materials containing more than one type of multivalent ligand and that ROMP is a useful method to synthesize such well-defined copolymers.
\r\n\r\n\r\n" }, { "name": "Cucullu, Mich\u00e8le Elise", "degree": "Masters", "year": "1999", "title": "Ruthenium Based Catalysts: Catalytic Dehalogenation of Chloroarenes and Syntheses of Bimetallic Carbene Complexes", "advisor": "Grubbs, Robert H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:11012023-172614654", "creators": [ { "name": { "family": "Cucullu", "given": "Mich\u00e8le Elise" }, "id": "Cucullu-Mich\u00e8le-Elise", "display_name": "Cucullu, Mich\u00e8le Elise" } ], "advisors": [ { "name": { "family": "Grubbs", "given": "Robert H." }, "id": "Grubbs-R-H", "orcid": "0000-0002-0057-7817", "role": "advisor", "display_name": "Grubbs, Robert H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/a64g-1585", "abstract": "[No Abstract]" }, { "name": "Tomooka, Craig Shigeru", "degree": "Masters", "year": "1999", "title": "Use of Manganese(V) Nitrides as Enantioselective Nitrogen-Transfer Reagents", "advisor": "Carreira, Erick Moran", "url": "https://resolver.caltech.edu/CaltechTHESIS:12062017-140954903", "creators": [ { "name": { "family": "Tomooka", "given": "Craig Shigeru" }, "id": "Tomooka-Craig-Shigeru", "display_name": "Tomooka, Craig Shigeru" } ], "advisors": [ { "name": { "family": "Carreira", "given": "Erick Moran" }, "id": "Carreira-E-M", "orcid": "0000-0003-1472-490X", "role": "advisor", "display_name": "Carreira, Erick Moran" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/6t7v-s157", "abstract": "Once activated, manganese(V) nitrides have been shown to efficiently transfer nitrogen to furanoid. glycals. This process, followed by hydrolysis, forms the corresponding amino alcohols in high yield and diastereoselectivity. The isolation of an intermediate oxazoline and the ability to form this oxazoline from the amino alcohol was also discovered. The formation of chiral manganese nitrides is also described. After considerable experimentation, the transfer of nitrogen in these cases resulted in enantiomeric excesses of up to 92% accompanied by high yields." }, { "name": "Hoang, Bac Hoa", "degree": "Masters", "year": "1998", "title": "Progress Towards the Total Synthesis of a Spermine-Conjugated Dynemicin Analog", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:08222013-144438603", "creators": [ { "name": { "family": "Hoang", "given": "Bac Hoa" }, "id": "Hoang-Bac-Hoa", "display_name": "Hoang, Bac Hoa" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/3g9z-nn03", "abstract": "Progress towards the synthesis of the spermine-conjugated Dynemicin analog 4 is\r\ndescribed. The synthetic route starts with the Michael addition of menthyl acetoacetate to\r\ntrans-ethyl crotonate followed by a Dieckman condensation to form the cyclohexanedione\r\n14 which, through a series of chemical reactions, is transformed into the quinone imine 6.\r\nKey features in the route include the Suzuki coupling reaction of the aryl boronic acid 11\r\nand the enol triflate 12, thermal deprotection/internal amidation of the biaryl 19, cis\r\naddition of the (Z)-enediyne 33 to the quinoline 25, intramolecular acetylide addition to a\r\ncarbonyl within the ketone 29, and an addition/elimination of the cyanophthalide to the\r\nquinone imine 6 to form the anthraquinone 36 utilizing the Kraus and Sugimoto\r\nmethodology." }, { "name": "Seidel, Peter Robert", "degree": "Masters", "year": "1996", "title": "Direct Decomposition of Nitric Oxide by Copper Containing ZSM-5", "advisor": "Davis, Mark E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:03242025-182317095", "creators": [ { "name": { "family": "Seidel", "given": "Peter Robert" }, "id": "Seidel-Peter-Robert", "display_name": "Seidel, Peter Robert" } ], "advisors": [ { "name": { "family": "Davis", "given": "Mark E." }, "id": "Davis-M-E", "orcid": "0000-0001-8294-1477", "role": "advisor", "display_name": "Davis, Mark E." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/ab1s-x455", "abstract": "Currently there is an enormous demand for nitric oxide decomposition catalysts and hydrocarbon-based selective catalytic reduction catalysts to eliminate NO. The incorporation of copper atoms into the pores of ZSM-5\r\nhas endowed this solid with the catalytic ability for the direct decomposition of NO to N2 and O2. This report describes the synthesis, characterization, ion-exchange, and reactivity of several ZSM-5 samples prepared by various methods. ZSM-5 is prepared using TPA and also by template-free synthesis methods. Ion-exchange was performed using copper acetate and a copper ethylene complex. Reaction studies include determining rates and turnover frequencies for certain ZSM-5 samples. It was found that ion-exchange with copper ethylene almost doubled the copper weight percent and the reaction rate compared to samples exchanged with copper acetate, however, the turnover frequencies were similar.
" }, { "name": "Zhu, Mei", "degree": "Masters", "year": "1996", "title": "Selective hydroxylation of small alkanes by the particulate methane monooxygenase", "advisor": "Chan, Sunney I.", "url": "https://resolver.caltech.edu/CaltechTHESIS:08212013-112742527", "creators": [ { "name": { "family": "Zhu", "given": "Mei" }, "id": "Zhu-M", "display_name": "Zhu, Mei" } ], "advisors": [ { "name": { "family": "Chan", "given": "Sunney I." }, "id": "Chan-S-I", "role": "advisor", "display_name": "Chan, Sunney I." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/qecc-y270", "abstract": "The particulate methane monooxygenase (pMMO) catalyzes the\r\noxidation of methane to methanol under ambient temperatures and\r\npressures. Other small alkanes and alkenes are also substrates of this\r\nenzyme. We measured and compared the initial rate constants of oxidation\r\nof small alkanes (C1 to C5) catalyzed by pMMO. Both primary and\r\nsecondary alcohols were formed from oxidation of n-butane and n-pentane.\r\nThe alcohols produced from alkane oxidation can be further oxidized,\r\nprobably by pMMO, to aldehydes and ketones. The apparent\r\nregioselectivity for n-butane and n-pentane is 100% 2-alcohols because the\r\nformation of primary alcohols is slower than further oxidation of these\r\nalcohols. The hydroxylation at the secondary carbons is highly\r\nstereoselective: (R)-alcohols are preferentially formed. The enantiomeric\r\nexcess increases slightly with decreasing reaction temperature. The steric\r\ncourse of hydroxylation on primary carbons was also studied by using\r\nisotopically substituted ethane: (S)- or (R)-CH_3-CHDT, and (S)- or (R)-CD_3-\r\nCHDT and the reactions were found to proceed with 100% retention of\r\nconfiguration. A primary isotopic effect of k_H/k_D=5.0 was observed in\r\nthese experiments." }, { "name": "Flatt, Brenton T.", "degree": "Masters", "year": "1995", "title": "Transition metal alkylidene complexes via the ring-opening of cyclopropenes", "advisor": "Grubbs, Robert H.", "url": "https://resolver.caltech.edu/CaltechETD:etd-10262007-082758", "creators": [ { "name": { "family": "Flatt", "given": "Brenton T." }, "id": "Flatt-B-T", "display_name": "Flatt, Brenton T." } ], "advisors": [ { "name": { "family": "Grubbs", "given": "Robert H." }, "id": "Grubbs-R-H", "role": "advisor", "display_name": "Grubbs, Robert H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/9zd6-rr52", "abstract": "NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document.\n\nThe first chapter details the preparation and structural characterization of a rhenium (VII) oxo-vinylalkylidene complex and discusses its activity in olefin metathesis reactions. A substitution reaction affords the rhenium (V) oxo-trisalkoxide precursor, a species that \nsurprisingly adopts a facial arrangement of three very bulky alkoxide ligands in its crystal structure. This complex reacts with 3,3-diphenylcyclopropene in a non-coordinating solvent to yield a mixture of two rhenium alkylidene isomers. Over time one species \npredominates and is isolated. An X-ray diffraction study of the isolated complex and [...] NMR studies of the isomerization process are described. Reactivity studies indicate that the isolated product demonstrates very limited olefin metathesis activity. However, the addition of Lewis acid cocatalysts to the rhenium alkylidene complex generates a much more active catalyst system, in particular, for the metathesis of cis-2-pentene. No propagating alkylidene species are observed during the metathesis reaction.\n\nThe second chapter describes the synthesis and characterization of a dicyclopropene compound from which the preparation of ROMP diinitiators is reasoned to be possible. The starting material-1,4-di(1-phenylvinyl)benzene-is readily prepared via a Grignard reaction and subsequent dehydration. A series of three steps analogous to those of the 3,3 diphenylcyclopropene synthesis yield the desired roduct-1,4-di(1-phenylcycloprop-2-enyl)benzene. Alternate pathways to the product also are proposed and the investigations are detailed. In particular, a biphasic cyclopropanation reaction using either bromoform or chloroform as a carbene source affords the respective dicyclopropane intermediates. Ultimately the syntheses of bis(metal alkylidene) complexes from reactions of this dicyclo-propene with various transition metal precursors have implications for the formation of polymers which propagate in two directions and for the preparation of triblock copolymers.\n" }, { "name": "Karp, Christoph D.", "degree": "Masters", "year": "1995", "title": "Photoelectrochemistry of Si/polymer and Si/metal/solution interfaces", "advisor": "Lewis, Nathan Saul", "url": "https://resolver.caltech.edu/CaltechETD:etd-10262007-085203", "creators": [ { "name": { "family": "Karp", "given": "Christoph D." }, "id": "Karp-C-D", "display_name": "Karp, Christoph D." } ], "advisors": [ { "name": { "family": "Lewis", "given": "Nathan Saul" }, "id": "Lewis-N-S", "role": "advisor", "display_name": "Lewis, Nathan Saul" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/7enk-wj52", "abstract": "Part I of this thesis describes the formation of a silicon/polypyrrole junction utilizing a new method of polypyrrole polymerization which was developed in the Lewis Group by Dr. Michael Freund. This new method involves the chemical oxidation of pyrrole to form smooth, conducting polypyrrole films upon solvent evaporation. This polymerization process allows semiconductor/polymer junctions to be formed without exposing the silicon surface to harmful oxidative currents used in electrochemical polymerizations. The studies described herein demonstrate the formation of a stable, rectifying junction between silicon and chemically polymerized polypyrrole.\n\nPart II of this thesis describes work related to a recent hypothesis regarding the charge-transfer processes of metal-coated silicon electrodes in methanol solutions, proposed by Ming Tan of the Lewis Group. The silicon is modified by depositing thin metal lines onto the surface, which facilitate electron-transfer between the silicon and the solution and limit direct charge transfer through the silicon/solution interface. The design of these devices allows examination of the interaction of semiconductor/metal and semiconductor/liquid junction characteristics as a function of the size and distribution of metal lines.\n" }, { "name": "Kephart, Susan E.", "degree": "Masters", "year": "1995", "title": "Synthetic and mechanistic studies on a silicon-mediated aldol reaction", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-10312007-082516", "creators": [ { "name": { "family": "Kephart", "given": "Susan E." }, "id": "Kephart-S-E", "display_name": "Kephart, Susan E." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/t9y9-zk34", "abstract": "No abstract submitted.\n\n" }, { "name": "Wang, Neng E.", "degree": "Masters", "year": "1995", "title": "Studies in dynamics", "advisor": "Marcus, Rudolph A.; Goddard, William A., III", "url": "https://resolver.caltech.edu/CaltechETD:etd-10292007-104923", "creators": [ { "name": { "family": "Wang", "given": "Neng E." }, "id": "Wang-Neng-E", "display_name": "Wang, Neng E." } ], "advisors": [ { "name": { "family": "Marcus", "given": "Rudolph A." }, "id": "Marcus-R-A", "role": "advisor", "display_name": "Marcus, Rudolph A." }, { "name": { "family": "Goddard", "given": "William A., III" }, "id": "Goddard-W-A-III", "role": "advisor", "display_name": "Goddard, William A., III" } ], "committee": [ { "name": { "family": "Marcus", "given": "Rudolph A." }, "id": "Marcus-R-A", "role": "chair", "display_name": "Marcus, Rudolph A." }, { "name": { "family": "Goddard", "given": "William A., III" }, "id": "Goddard-W-A-III", "role": "member", "display_name": "Goddard, William A., III" }, { "name": { "family": "Wang", "given": "Zhen-Gang" }, "id": "Wang-Zhen-Gang", "role": "member", "display_name": "Wang, Zhen-Gang" } ], "option_major": [ "chemistry" ], "doi": "10.7907/j1ch-3v41", "abstract": "NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document.\r\n\r\nIn this thesis, three parts of my work are reported. The first part of the work was done with Prof. Rudy Marcus, the second and third parts of the work were done with Prof. Bill Goddard. Here I would like to summarize the results from each part briefly.\r\n\r\nIn the first part, we propose doing Scanning Tunneling Microscopy(STM) current calculations with a new model in the spheroidal coordinate system. The tip is modeled as a hyperboloid. The electrostatic potential part of this model is solved exactly. The free electron model of the whole system is also solved exactly.\r\n\r\nIn the second part, we found that the Nose Canonical Molecular Dynamics, the most commonly used CMD method, leads to the wrong heat capacity for the system and hence is inconsistent with the thermodynamics. To solve this problem, we propose Two Nose variable Dynamics by changing the dimensionality of the Nose variable s and its conjugate [...] from one- to two-dimension.\r\n\r\nIn the third part, The exact expression for the quantum statistical partition function in the canonical ensemble is given. The physical interpretation of each term for N-particle system is discussed. The new formula is applied to the weakly degenerate quantum ideal case. By analyzing each term in the expansion, it is possible that this canonical partition function can be applied to cases where both quantum correlation effects and particle interactions are important.\r\n" }, { "name": "Singleton, Jennifer Wales", "degree": "Masters", "year": "1994", "title": "Affinity Cleavage of Double-Stranded DNA Directed by a RecA Nucleoprotein Filament Containing an Oligonucleotide-EDTA\u2022Fe(II)", "advisor": "Dervan, Peter B.", "url": "https://resolver.caltech.edu/CaltechTHESIS:09142018-083120243", "creators": [ { "name": { "family": "Singleton", "given": "Jennifer Wales" }, "id": "Singleton-Jennifer-Wales", "display_name": "Singleton, Jennifer Wales" } ], "advisors": [ { "name": { "family": "Dervan", "given": "Peter B." }, "id": "Dervan-P-B", "role": "advisor", "display_name": "Dervan, Peter B." } ], "committee": [ { "name": { "family": "Dervan", "given": "Peter B." }, "id": "Dervan-P-B", "role": "member", "display_name": "Dervan, Peter B." } ], "option_major": [ "chemistry" ], "doi": "10.7907/x3y9-dk45", "abstract": "Escherichia coli RecA protein promotes strand exchange between two homologous DNAs by polymerizing on single-stranded DNA to form nucleoprotein filaments which then bind to a homologous sequence of duplex DNA. Joint formation between the RecA protein and three strands of DNA is followed by strand exchange in which the original single strand is inserted into the duplex while the homologous duplex strand is displaced out. The structures of the strand exchange intermediates formed by the RecA protein have not been elucidated. We review studies aimed at determining such structures and we report the use of affinity cleaving techniques to probe the structure of the joint molecule formed between a RecA-oligonucleotide filament and duplex DNA by incorporating a thymidine-EDTA\u2022Fe (T*) into the oligonucleotide of the filament. In our study, we find that the nucleoprotein filament binds antiparallel to the complementary strand within the homologous sequence of DNA and that it is associated more strongly with the complementary strand than with the homologous strand of the duplex.
\r\n" }, { "name": "Stroud, Carrie Kim", "degree": "Masters", "year": "1994", "title": "Collinear Reaction Dynamics and Hydrodynamic Analysis of the Vibrationally Excited Cl + HCl \u2192 ClH + Cl, Cl + DCl \u2192 ClD + Cl and Cl + TCl \u2192 ClT + Cl Reactions on Two Leps Surfaces", "advisor": "Kuppermann, Aron", "url": "https://resolver.caltech.edu/CaltechTHESIS:09062018-160235948", "creators": [ { "name": { "family": "Stroud", "given": "Carrie Kim" }, "id": "Stroud-Carrie-Kim", "display_name": "Stroud, Carrie Kim" } ], "advisors": [ { "name": { "family": "Kuppermann", "given": "Aron" }, "id": "Kuppermann-A", "role": "advisor", "display_name": "Kuppermann, Aron" } ], "committee": [ { "name": { "family": "Kuppermann", "given": "Aron" }, "id": "Kuppermann-A", "role": "member", "display_name": "Kuppermann, Aron" } ], "option_major": [ "chemistry" ], "doi": "10.7907/aqts-fq51", "abstract": "Quantum dynamical calculations for the collinear Cl + HCl \u2192 ClH + Cl, Cl + DCl \u2192 ClD + Cl, and Cl + TCl \u2192 ClT + Cl reactions on low and high barrier potential energy surfaces are presented and discussed within the framework of the hyperspherical coordinate representation. Vibrational excitation of the reagent diatomic is found to decrease the reaction rate for the low barrier surface and increase the reaction rate for the high barrier surface. Quantum mechanical streamline calculations and tunneling fractions are used for analysis, and discussion of the results is made in terms of the topology of the potential surface, in which the skew angle and barrier height of the system play a leading role in explaining the dynamics of the reaction.
" }, { "name": "Sun, James Te", "degree": "Masters", "year": "1994", "title": "Chemical Sensing with Surface Acoustic Wave Devices", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03172025-153654379", "creators": [ { "name": { "family": "Sun", "given": "James Te" }, "id": "Sun-James-Te", "display_name": "Sun, James Te" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/fm93-5h73", "abstract": "There is much current interest in developing new techniques for\r\nthe continuous monitoring of chemical environments. However, as there\r\nare many applications where the excessive size and power demands of\r\nconventional sensors have precluded their use, interest in microsensors\r\nsuch as the surface acoustic wave (SAW) device has been spurred by\r\ntheir small size, ruggedness, sensitivity, and low power consumption.\r\nIn this work, 158 MHz SAW oscillators coated with organic polymers\r\nand inorganic crystallites were tested as model systems for vapor\r\nsensors that can monitor the level of humidity and carbon dioxide in a\r\ncontinuous stream of nitrogen. All coatings exhibited responses to water\r\nvapor on the order of kilohertz, while the responses to carbon dioxide\r\nwere significantly (generally one order of magnitude) smaller.\r\nInterferences by the presence of both water and CO2 on the SAW device\r\nsensitivity were observed with poly-(ethylenimine) (PEI) coatings as\r\nevidenced by the large extent of hysteresis. P El coatings were also\r\nfound to exhibit anomalous directions in frequency shifts when exposed\r\nto pulses of humidified CO2, as did poly-(4-vinylpyridine) (PVP)\r\ncoatings for lower humidity levels. ZSM-5 coatings, however, showed\r\nno evidence of such interference between water and CO2." }, { "name": "Dawn, Douglas David", "degree": "Masters", "year": "1993", "title": "Saving Stratospheric Ozone: Putting the Problem in Perspective and Evaluating Hydrohalocarbons and their Mixtures as Potential Solutions", "advisor": "Chan, Sunney I.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04132026-170425336", "creators": [ { "name": { "family": "Dawn", "given": "Douglas David" }, "id": "Dawn-Douglas-David", "display_name": "Dawn, Douglas David" } ], "advisors": [ { "name": { "family": "Chan", "given": "Sunney I." }, "id": "Chan-S-I", "orcid": "0000-0002-5348-2723", "role": "advisor", "display_name": "Chan, Sunney I." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/k64d-7m04", "abstract": "Stratospheric ozone depletion by halocarbon gases is reviewed. Some\r\ninsight is offered to explain the technical and political difficulties currently\r\nfacing industrial producers and end use consumers. Industry estimates that\r\n40% of the ozone destruction caused by halocarbons from the United States\r\nis a result of air conditioning and refrigeration.
\r\n\r\nA partial solution employing mixtures of gases relatively harmless to the\r\nozone layer is investigated to replace refrigerant fluids currently in use.\r\nComputer subroutines developed at the National Institute of Standards and\r\nTechnology for modeling mixtures using a semi-empirical equation of state\r\nare utilized to generate results. Superior properties are predicted for an\r\napplication defined within the temperature range of human comfort.\r\nBenefits and shortcomings are discussed that are both specifically applicable\r\nto this approach and generally applicable to the development of\r\nreplacements.
" }, { "name": "Forstner, Hali Janine Lala", "degree": "Masters", "year": "1993", "title": "Molecular Speciation of Secondary Organic Aerosol from Various Anthropogenic Hydrocarbons", "advisor": "Seinfeld, John H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:06272025-191230924", "creators": [ { "name": { "family": "Forstner", "given": "Hali Janine Lala" }, "id": "Forstner-Hali-Janine-Lala", "display_name": "Forstner, Hali Janine Lala" } ], "advisors": [ { "name": { "family": "Seinfeld", "given": "John H." }, "id": "Seinfeld-J-H", "orcid": "0000-0003-1344-4068", "role": "advisor", "display_name": "Seinfeld, John H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/1dqr-8g94", "abstract": "Gas-to-particle conversion is a ubiquitous process in the\r\natmosphere, understanding its detailed chemistry and physics\r\nwill allow one to predict the effects of primary gaseous and\r\nparticulate emissions on airborne particulate matter composition and size. This research proposes to determine the mechanisms of secondary organic aerosol formation in the\r\natmosphere for a number of important anthropogenic\r\nhydrocarbons. A 6 m3 outdoor smog chamber will be used to\r\ngenerate organic aerosols for molecular speciation analysis by gas chromatography/mass spectrometry. Gas-phase photooxidation mechanisms of the parent hydrocarbon will be\r\nformulated based on the results from this analysis." }, { "name": "Fiala, Brenda L.", "degree": "Masters", "year": "1992", "title": "Ortho-chain-bridged polyacetylene via the ring-opening metathesis polymerization", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:10032011-105315204", "creators": [ { "name": { "family": "Fiala", "given": "Brenda L." }, "id": "Fiala-B-L", "display_name": "Fiala, Brenda L." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/m5rd-gg62", "abstract": "Chain-bridged poly(acetylene) polymers have previously been\r\nsynthesized with meta- and para- linkages to the substituents. In this paper, two ortho-chain-bridged poly(cyclooctatetraene) polymers demonstrate the effects of an enforced cis linkage approximately every fourth carbon-carbon double bond in a poly(acetylene)-like polymer.\r\n" }, { "name": "Haney, Susan Elaine", "degree": "Masters", "year": "1992", "title": "Investigation of low-valent ruthenium aquo complexes", "advisor": "Bercaw, John E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10032011-090148072", "creators": [ { "name": { "family": "Haney", "given": "Susan Elaine" }, "id": "Haney-S-E", "display_name": "Haney, Susan Elaine" } ], "advisors": [ { "name": { "family": "Bercaw", "given": "John E." }, "id": "Bercaw-J-E", "role": "advisor", "display_name": "Bercaw, John E." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/bd27-j183", "abstract": "The work presented in this thesis investigates the synthesis of low oxidation state coordination complexes of ruthenium incorporating the anionic ligand, [CpCo(P(O)(OMe)_2)_3]-,(L_(OMe)). Several routes to RuL_(OMe)(H_2O)_3^+ are outlined. These routes produced two major products, possibly related by acid-base chemistry.
\r\n\r\nA new dimeric ruthenium aquo species with the proposed structure [Ru(III)L_(OMe)(H_2O)(\u00b5-OH)_2OTs_2 was isolated. This complex does not provide a straightforward route to the target monomeric oxo compounds, but could conceivably provide a entry into synthesis of ruthenium dimers containing arnines and other ligands.
\r\n\r\nFinally, a new route to [Ru(IV)(H_20)(\u00b5-O)]_2OTf_2 was discovered which is more convenient and is higher yielding than the previously published procedure.
" }, { "name": "Rico, Rudolph J.", "degree": "Masters", "year": "1992", "title": "Quantum-mechanical studies of vanadium oxides", "advisor": "Goddard, William A., III", "url": "https://resolver.caltech.edu/CaltechTHESIS:10042011-094257165", "creators": [ { "name": { "family": "Rico", "given": "Rudolph J." }, "id": "Rico-R-J", "display_name": "Rico, Rudolph J." } ], "advisors": [ { "name": { "family": "Goddard", "given": "William A., III" }, "id": "Goddard-W-A-III", "role": "advisor", "display_name": "Goddard, William A., III" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/2set-6e48", "abstract": "A variety of V-O systems were examined in order to model the catalytic site for VPO-catalyzed conversion of butane to maleic anhydride. All V-O systems examined could be described as a V-O triple bond, with a covalent \u03c3-bond and two \u03c0-bonds, and a bond length of approximately 1.56-1.60 \u00c5. The nature of the \u03c0-bonds varied. In VOCl_4^(3-) and VOCl_(2-), the \u03c0-bonds were both described as donor-acceptors. All other systems displayed one covalent bond and one donor-acceptor bond. Resonance between the two \u03c0-bonds was displayed for four-chloride C_(4v) VOCl_4^(2-/-). Optimized C_(2v) geometries for VOCl_4^(2-/-) appear to be the result of this resonance, in which the wavefunction and geometry represent one resonance state of the overall C_(4v) system, in which one \u03c0 -bond is highly covalent, and the other highly donor-acceptor. The C_(4v) system is lower in energy than the C_(2v) system at all levels of theory (HF, CASSCF, MRCI) except GVB(3/6)-PP. VOCl_2^(0/+) calculations show strong similarities to C_(2v) VOCl_4^(2-/-) in both V-O bond description and geometry, suggesting that these systems\r\ncan be described as C_(2v) VOCl_4^(2-/-) systems without the axial chlorides. VO+ and VOCl_3 results, for which experimental data exists, support the descriptions of geometry and bonding given. V(V) systems display a strong degree of covalent character to the chlorides (as does VO_3 to the bound oxygen molecule), but this effect decreases\r\nsignificantly as the V(3d\u03b4 )-orbitals are occupied. Snap bond calculations indicate that the V(V)-O bond is approximately 28 kcal/mol weaker than the V(lV)-O bond - this may be due to the increased V-C1 interaction in the products of the V(V) bondbreaking.\r\n" }, { "name": "Yang, Maximillian Y.", "degree": "Masters", "year": "1992", "title": "Progress on the synthesis of 1,2,3,5,9-cyclodecapentaen-7-yne and supporting studies", "advisor": "Myers, Andrew G.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10042011-102102178", "creators": [ { "name": { "family": "Yang", "given": "Maximillian Y." }, "id": "Yang-M-Y", "display_name": "Yang, Maximillian Y." } ], "advisors": [ { "name": { "family": "Myers", "given": "Andrew G." }, "id": "Myers-A-G", "role": "advisor", "display_name": "Myers, Andrew G." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/bfhp-k953", "abstract": "Progress on the synthesis of 1,2,3,5,9-cyclodecapentaen-7-yne (1), a compound structurally related to both (Z)-1,2,4-heptatrien-6-yne and the activated\r\ncore of neocarzinostatin chromophore, is reported. The novel compound 1 is of theoretical interest as an example of a monocyclic 10-membered ring that fulfills the aromaticity requirements of H\u00fcckel's rule. The alcohol 24, envisioned to serve as a possible precursor to 1, has been synthesized.
\r\n\r\nIn related, collaborative studies, 1-bromo-4-trimethylsilylnaphthalene, 1-bromo-5-trimethylsilylnaphthalene, 2-bromo-7-trimethylsilylnaphthalene, 1-chloro-\r\n4-trimethylsilylnaphthalene, 1-chloro-5-trimethylsilylnaphthalene, and 2-chloro-7-\r\ntrimethylsilylnaphthalene have been synthesized. These compounds will be used in gas-phase studies as precursors to the corresponding naphthalene biradicals. These studies will determine the heat of formation of each corresponding \r\nnaphthalene biradical.
\r\n" }, { "name": "Braatz, Richard Dean", "degree": "Masters", "year": "1991", "title": "\u03bc-Sensitivities as an Aid for Robust Identification", "advisor": "Morari, Manfred", "url": "https://resolver.caltech.edu/CaltechTHESIS:06272025-182529568", "creators": [ { "name": { "family": "Braatz", "given": "Richard Dean" }, "id": "Braatz-Richard-Dean", "orcid": "0000-0003-4304-3484", "display_name": "Braatz, Richard Dean" } ], "advisors": [ { "name": { "family": "Morari", "given": "Manfred" }, "id": "Morari-M", "orcid": "0000-0002-7696-5058", "role": "advisor", "display_name": "Morari, Manfred" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/4ckj-5r83", "abstract": "Identification for a model for robust control design is more complicated than for the standard linear system transfer function model-the structure of the uncertainty as well as bounds on its size must be determined. It is especially unclear as to which parts of the system should be better modeled to improve robust performance. This paper addresses this question through some new tools, the \u03bc-sensitivities." }, { "name": "Smith, Paul Andrew", "degree": "Masters", "year": "1991", "title": "A Reexamination of Tryptophan Fluorescence in Cytochrome c Oxidase", "advisor": "Khundkar, Lutfur R.; Perry, Joseph W.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04192011-145437221", "creators": [ { "name": { "family": "Smith", "given": "Paul Andrew" }, "id": "Smith-P-A", "display_name": "Smith, Paul Andrew" } ], "advisors": [ { "name": { "family": "Khundkar", "given": "Lutfur R." }, "id": "Khundkar", "role": "advisor", "display_name": "Khundkar, Lutfur R." }, { "name": { "family": "Perry", "given": "Joseph W." }, "id": "Perry-J-W", "role": "advisor", "display_name": "Perry, Joseph W." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/5tq9-2s50", "abstract": "Cytochrome c oxidase links reduction of oxygen with the pumping of protons across the inner mitochondrial membrane. Recently it has been shown that only two of the four electron transfers to the oxygen binding site are coupled with proton translocation. The discovery implies that there is a conformational switch between pumping and non-conformational changes. Gating conformational transitions occur in each cycle of the pump when electrons and protons are alternatively accessible to either the inside or outside of the membrane. Such transitions are linked to the redox state of the coupling site. The unloaded/loaded transition, on the other hand, depends on the intermediate at the oxygen binding site and is not part of the pumping cycle.\r\n\r\nA 16 nm red-shift in the tryptophan emission maximum of cytochrome oxidase upon reduction of the enzyme with dithionite was reported earlier [Copeland, R.A., Smith, P.A., and Chan, S.I. (1987) Biochemistry 26, 7311]. As such redox-linked change could be an important probe of pumping transitions, the fluorescence change of cytochrome oxidase upon reduction with ascorbate and cytochrome c was measured. The absence of a shift led to the reevalution of the earlier experiments for inner filter effects. The earlier experiments were reproduced with proper optical controls, and a method for reconstructing absorbance aftifacts from the reported fluourescence spectra was devised. Tryptophan fluourescence lifetimes were also measured. All the data support the conclusion that the earlier reports of a redox-linked fluourescence change were artifacts and that the other transient changes in fluorescence which have been measured cannot be associated with either the unloaded/loaded transition or a gating transition." }, { "name": "Proteau, Philip Jerome", "degree": "Masters", "year": "1990", "title": "Neocarzinostatin chromophore: structural, mechanistic, and synthetic studies", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:08122014-131021849", "creators": [ { "name": { "family": "Proteau", "given": "Philip Jerome" }, "id": "Proteau-Philip-Jerome", "display_name": "Proteau, Philip Jerome" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/tmh7-8559", "abstract": "Neocarzinostatin chromophore 1 is the active component of the antitumor antibiotic\r\nneocarzinostatin (NCS). The chromophore reacts with thiols to form a highly strained\r\ncumulene-enyne species which rapidly rearranges to a biradical intermediate which can\r\nabstract hydrogen atoms from DNA, leading to strand cleavage. DNA damage is the\r\nproposed source of biological activity for NCS. The structure of the methyl thioglycolate\r\nmonoadduct 2 of NCS chromophore, including the absolute stereochemistry, was\r\ndetermined by NMR studies. The presence of the cumulene-enyne intermediate and the\r\nrearrangement to a biradical were supported by data from low temperature NMR\r\ninvestigations. Also included are synthetic approaches to NCS chromophore model\r\ncompounds based on intramolecular addition of an acetylide to an aldehyde." }, { "name": "Brown, Thomas Kingsley", "degree": "Masters", "year": "1989", "title": "Structure and function of neuronal postsynaptic densities of the central nervous system", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04022010-152248735", "creators": [ { "name": { "family": "Brown", "given": "Thomas Kingsley" }, "id": "Brown-T-K", "display_name": "Brown, Thomas Kingsley" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/qzpb-d552", "abstract": "No abstract." }, { "name": "Fuhry, Mary Ann M.", "degree": "Masters", "year": "1989", "title": "Progress on the synthesis of a model system for neocarzinostatin chromophore", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04072010-111308897", "creators": [ { "name": { "family": "Fuhry", "given": "Mary Ann M." }, "id": "Fuhry-M-A-M", "display_name": "Fuhry, Mary Ann M." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/tj6s-2x96", "abstract": "No abstract." }, { "name": "Novak, Julia Anne", "degree": "Masters", "year": "1989", "title": "The quintet state of a partially localized, hydrocarbon tetraradical: cyclobutane as a general ferromagnetic coupling unit", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04022010-085334137", "creators": [ { "name": { "family": "Novak", "given": "Julia Anne" }, "id": "Novak-J-A", "display_name": "Novak, Julia Anne" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/9az5-6648", "abstract": "The partially localized tetraradical 22 has been generated at temperatures of 77 K and below in 2-methyltetrahydrofuran and poly(methylmethacrylate) \r\nmatrices, and directly observed by EPR spectroscopy. The evolution of the EPR spectrum resulting from prolonged photolysis of the bisdiazene precursor 20 indicates a two-photon process, wherein a triplet spectrum (assigned unambiguously to the monoazobiradical) gradually gives way to a quintet spectrum, ascribed to the target tetraradical. The observed quintet state is tentatively identified as the ground state of the tetraradical, based on design considerations, the fact that the quintet spectrum is intense at temperatures as low as 3.8 K, and preliminary Curie Law studies. The thermal stability of 22 (indefinitely stable in the dark at 77 K) is an unexpected \r\nattribute of this molecule; no other cyclobutanediyl studied thus far has exhibited similar sturdiness at temperatures above ca. 60 K. Two synthetic routes to the prerequisite bisfulvene 15 are discussed." }, { "name": "Sipes, Christopher N.", "degree": "Masters", "year": "1989", "title": "Real-time measurements of a bimolecular reaction", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04022010-095849815", "creators": [ { "name": { "family": "Sipes", "given": "Christopher N." }, "id": "Sipes-C-N", "display_name": "Sipes, Christopher N." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/3527-zy08", "abstract": "A method is described for the initiation of a bimolecular reaction with a laser. This allows the time resolution of bimolecular kinetics with ultrafast laser spectroscopy. Such kinetics are described for the case of \r\nH + CO_2 => OH + CO. The rise in OH is measured and examined via the proper intermediate-mediated kinetics -- the \"biphasic\" expression. The effect of restricting the impact parameter of the hydrogen atom on the carbon dioxide is also considered." }, { "name": "Sogo, Steven G.", "degree": "Masters", "year": "1989", "title": "Studies of novel methods of gene transfer and gene regulation in eukaryotic cells", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-075936771", "creators": [ { "name": { "family": "Sogo", "given": "Steven G." }, "id": "Sogo-S-G", "display_name": "Sogo, Steven G." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/p38j-0a87", "abstract": "No abstract." }, { "name": "Totten, Nancy Susanne Demcak", "degree": "Masters", "year": "1989", "title": "Examining the transferrin-transferrin receptor system as a possible mechanism for cell specific targeting with liposomes", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-094148072", "creators": [ { "name": { "family": "Totten", "given": "Nancy Susanne Demcak" }, "id": "Totten-N-S-D", "display_name": "Totten, Nancy Susanne Demcak" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/2qfc-mj80", "abstract": "This research focuses on targeting capabilities which may be applied for delivery of liposomes to T cells. Two methods of targeting were investigated. The first involved IgG purified from goat antisera to aportion of the viral envelope of Human Immunodeficiency Virus (HIV). The \r\nIgG was derivatized with the N-hydroxysuccinimide ester of palmitic acid (NHSP) to increase its hydrophobicity so that it could be incorporated into the lipid bilayer of egg phosphatidylcholine liposomes.\r\n\r\nThe second method used transferrin to coat liposomes made from egg phosphatidylcholine and egg phosphatidylethanolamine, 5:1 weight ratio, respectively. In this method the transferrin receptor (TfR) serves as a \r\ntarget for the delivery of transferrin (Tf) coated liposomes to cells.\r\n\r\nFrom previous observations made at the City of Hope as well as data from a resent paper, HIV infected cells appear to have an increased affinity for Tf. This increased affinity is most likely associated with an increase in cell surface TfRs. The H-9 cell line, which can be infected with HIV, has been characterized for the number of TfRs per cell and for the binding of Tf.\r\n\r\nAttaching IgG or Tf to a liposome will alter the protein structure. Thus, the receptor-ligand affinity characteristics of IgG as well as the affinity of iron for Tf and of Tf-Fe for TfR will change. As a result, the \r\ntype of association which links IgG or Tf to the liposome will affect the targeting ability of the IgG or Tf coated liposomes. Many methods of associating IgG with liposomes have been studied. The method of choice is one of the most successful ways for the use of liposome delivery. It involves the attachment of palmitoyl chains to the IgG \r\nfollowed by insertion of the now hydrophobic IgG into the lipid membrane. Only a few procedures for attaching Tf and liposomes have previously been tried. I have examined a new method for attaching Tf to liposomes, involving the use of water soluble carbodiimide. The crosslinking of Tf and liposome has been observed with a maximum efficiency of 1 Tf molecule for 4 liposomes. For both IgG and Tf coated liposomes, an average diameter of 45-50nm was determined.\r\n" }, { "name": "Worthen, Denise Lynne", "degree": "Masters", "year": "1989", "title": "Lactose binding to the E. coli symport protein Lac permease", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:11242009-093118312", "creators": [ { "name": { "family": "Worthen", "given": "Denise Lynne" }, "id": "Worthen-D-L", "display_name": "Worthen, Denise Lynne" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/kkcr-mc09", "abstract": "Lac permease is a symport protein which responsible for the active accumulation of lactose in E. coli. The protein utilizes the energy from the downhill translocation of protons to drive uphill accumulation of lactose. This work reports the direct measurement by proton NMR of lactose binding to lac permease of E. coli membrane vesicles. The technique allows the determination of the K_d of lactose binding to lac permease binding sites. The results presented here show that the assay is specific for lac permease binding sites and that the assay can distinguish differences in binding affinity for different site specific mutants of lac permease. Determination of the Kd for lactose binding is important in determining which residues are important for lactose binding.\r\n" }, { "name": "Claeys, Ivan Lode Andr\u00e9 Maria", "degree": "Masters", "year": "1988", "title": "Experimental and Numerical Study of Molecular Rotational Diffusion in Gel-Like Media", "advisor": "Arnold, Frances Hamilton; Brady, John F.", "url": "https://resolver.caltech.edu/CaltechTHESIS:02122025-215432111", "creators": [ { "name": { "family": "Claeys", "given": "Ivan Lode Andr\u00e9 Maria" }, "id": "Claeys-Ivan-Lode-Andr\u00e9-Maria", "display_name": "Claeys, Ivan Lode Andr\u00e9 Maria" } ], "advisors": [ { "name": { "family": "Arnold", "given": "Frances Hamilton" }, "id": "Arnold-F-H", "orcid": "0000-0002-4027-364X", "role": "advisor", "display_name": "Arnold, Frances Hamilton" }, { "name": { "family": "Brady", "given": "John F." }, "id": "Brady-J-F", "orcid": "0000-0001-5817-9128", "role": "advisor", "display_name": "Brady, John F." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/fdsw-x095", "abstract": "The hindered rotational diffusion of biopolymers in porous or fibrous media\r\nplays a significant role in many industrial and natural processes. Nuclear magnetic\r\nrelaxation experiments can be used to investigate how the gel matrix impedes the\r\ntumbling of molecules trapped in its pores. Indeed, molecular motions influence\r\nthe relaxation rate by causing fluctuations of the local magnetic field experienced\r\nby the nuclear spins. Hence a measurement of relaxation times allows one to monitor\r\nthe rotational diffusion of rigid molecules in gels and to detect matrix-induced\r\nanisotropic behavior. Experiments examining the 31P relaxation of cGMP trapped\r\nin polyacrylamide gels showed more than a threefold decrease in the rotational diffusion\r\ncoefficient when the gel concentration was brought from zero to 30%. Similar\r\nexperiments in agarose gels prove that nuclear magnetic relaxation measurements\r\ncan effectively be used to extract valuable information about rotational diffusion\r\ninside gels.
\r\n\r\nA Stokesian dynamics simulation of molecular diffusion in fibrous environments\r\nwill complement the experimental studies. The mobility interactions between prolate\r\nspheroids in low Reynolds number linear flows have been derived. The expressions\r\nare exact at the level of forces, torques and stresslets, and the results are cast\r\nin a form suitable for numerical calculations. This extension of Stokesian dynamics\r\nto non-spherical particles forms the groundwork for computationally efficient,\r\nhydrodynamically accurate simulations of suspensions of rodlike particles.
" }, { "name": "Heil, Ann Terese", "degree": "Masters", "year": "1988", "title": "Movement of a Spherical Brownian Particle Between Infinite Parallel Plates: Hindered Dispersion and Sedimentation", "advisor": "Brady, John F.", "url": "https://resolver.caltech.edu/CaltechTHESIS:03192013-151818424", "creators": [ { "name": { "family": "Heil", "given": "Ann Terese" }, "id": "Heil-A-T", "display_name": "Heil, Ann Terese" } ], "advisors": [ { "name": { "family": "Brady", "given": "John F." }, "id": "Brady-J-F", "role": "advisor", "display_name": "Brady, John F." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/gypy-h364", "abstract": "The dispersion of an isolated, spherical, Brownian particle immersed in a\r\nNewtonian fluid between infinite parallel plates is investigated. Expressions are\r\ndeveloped for both a 'molecular' contribution to dispersion, which arises from\r\nrandom thermal fluctuations, and a 'convective' contribution, arising when a shear\r\nflow is applied between the plates. These expressions are evaluated numerically\r\nfor all sizes of the particle relative to the bounding plates, and the method of\r\nmatched asymptotic expansions is used to develop analytical expressions for the\r\ndispersion coefficients as a function of particle size to plate spacing ratio for small\r\nvalues of this parameter.
\r\n\r\nIt is shown that both the molecular and convective dispersion coefficients decrease\r\nas the size of the particle relative to the bounding plates increase. When the\r\nparticle is small compared to the plate spacing, the coefficients decrease roughly\r\nproportional to the particle size to plate spacing ratio. When the particle closely\r\nfills the space between the plates, the molecular dispersion coefficient approaches\r\nzero slowly as an inverse logarithmic function of the particle size to plate spacing\r\nratio, and the convective dispersion coefficent approaches zero approximately\r\nproportional to the width of the gap between the edges of the sphere and the\r\nbounding plates.
\r\n" }, { "name": "Lewis, Michael Robert", "degree": "Masters", "year": "1988", "title": "Synthesis of modified ribonucleosides and oligoribonucleotide hybridization probes", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04132010-091809823", "creators": [ { "name": { "family": "Lewis", "given": "Michael Robert" }, "id": "Lewis-M-R", "display_name": "Lewis, Michael Robert" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/0x5t-me74", "abstract": "Two strategies for the construction of chemically modified, DNA cleaving oligoribonucleotide probes are described. In the first strategy, the synthetic substrate 5-(3-aminoallyl)uridine 5'-triphosphate (AA-UTP, 1) is reacted with RNA polymerase II to synthesize an aminoallyl-oligoribonucleotide, and the DNA cleaving moiety is introduced by nonspecific, posttranscriptional derivatization of the primary amine groups of the modified RNA. The second strategy involves the incorporation of a modified ribonucleoside 3',5'-bisphosphate, covalently tethered to a DNA cleaving functionality, into an oligoribonucleotide by reaction with T4 RNA ligase. A general method for the chemical synthesis of ribonucleoside 3',5'-bisphosphates was developed. Using this method, uridine 3',5'-bisphosphate (pUp, 2) was synthesized in six steps with an overall yield of 14%. A modified pUp derivative, 5-(3-(3-nitrophenoxy)acetamidoally1)-, uridine 3',5'-bisphosphate (NA-pUp, 12), was also synthesized with an overall yield of 3% for nine steps. The RNA polymerase substrate 1 was prepared by known methods and tested for compatibility with 17 RNA polymerase II in an in vitro \"run-off' transcription system. The incorporation of AA-UTP by 17 RNA polymerase was found to be less efficient than that of uridine 5'-triphosphate (UTP), in contrast to results reported for SP6 RNA polymerase. In vitro transcription synthesis of oligoribonucleotides and aminoallyl-oligoribonucleotides by SP6 RNA polymerase gave irreproducible results. In the Ti RNA polymerase system, transcription synthesis produced heterogeneous mixtures of oligoribonucleotides or aminoallyl-oligoribonucleotides. Analysis of the transcription products by high-resolution gel electrophoresis showed that the distribution of transcripts did not vary significantly with buffer conditions or template end structure.\r\n" }, { "name": "McKinley, Lindsay K.", "degree": "Masters", "year": "1988", "title": "A study of several 1,3-cyclobutanediyls by ft-ir and computational techniques", "advisor": "Dougherty, Dennis A.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04062010-131315633", "creators": [ { "name": { "family": "McKinley", "given": "Lindsay K." }, "id": "McKinley-L-K", "display_name": "McKinley, Lindsay K." } ], "advisors": [ { "name": { "family": "Dougherty", "given": "Dennis A." }, "id": "Dougherty-D-A", "role": "advisor", "display_name": "Dougherty, Dennis A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/q9v0-5082", "abstract": "We have studied the photolytic decomposition of 2,3-diazabicyclo[2.2.1]hept-2-ene (Closs' azo) by FT-IR spectroscopy. While no transient species were detected, the photolysis product was exclusively bicyclopentane, as compared to Closs' result of 1:30 cyclopentene: bicyclopentane. The reasons for this difference are unclear; it may be due to our choice of argon for a matrix material. It has been previously shown that argon increases ISC rates compared to the first row elements.\r\n\r\nWe have also studied the photolytic decomposition of 1,4-diethy1-2,3-diazabicyclo[2.1.1]hex-2-ene. In this case, we have evidence that an intermediate exists, probably the diazenyl biradical formed by cleavage of a C-N bond. This intermediate has been detected by its decay to the starting diazene with a half-life of roughly 2 min. During the course of this investigation, the 1,4-diethyl diazene has been synthesized using a slight variation of methods previously developed in our group.\r\n\r\nWe have partially redesigned the FT-IR spectrometer in order to facilitate our investigations. Specifically, we have used a lens and mirror system to allow for photolysis inside the spectrometer of compounds deposited on the Displex window. This adaptation greatly reduces the time required for spectral acquisition.\r\n\r\nFinally, we have undertaken an ab initio study of the biradical 1,3-dietheny1-1,3-cyclobutanediy1 at the Hartree-Fock level. The results of the study show a high concentration of spin density on the ring carbons of the triplet. This difference with experimental results might be ameliorated by an inclusion of configuration interaction, specifically an MCSCF treatment." }, { "name": "Baldwin-Zuschke, Brenda Janet", "degree": "Masters", "year": "1986", "title": "Investigations of the Effect of Antigen Binding Upon Tryptophan Reactivity in Immunoglobulin G", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04052010-153132274", "creators": [ { "name": { "family": "Baldwin-Zuschke", "given": "Brenda Janet" }, "id": "Baldwin-Zuschke-Brenda-Janet", "display_name": "Baldwin-Zuschke, Brenda Janet" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/pwp3-7532", "abstract": "A ^3H/^(14)C-labelled reagent that reacts specifically with tryptophan residues, was used to monitor the reactivity of tryptophans in the Fc and Fab portions of IgG upon binding DNP-gly, (DNP)_1-cytochrome c, and (DNP)_8-cytochrome c. Binding of monovalent antigen caused a decrease in the reactivity of tryptophan residues in the Fc by 18%; binding of multivalent antigen caused decreases in the reactivity of tryptophan residues in Fc by 21% and Fab by 12%. Experiments to elucidate the interaction between IgG and complement component C4 were attempted.\r\n\r\nFuture studies include further characterization of (DNP)_1-cytochrome c and-the complement fixation capability of IgM-ABPC22 with monovalent antigen. Also planned is an investigation of the interaction of C4 with IgM in soluble antibody-antigen complexes." }, { "name": "Fourkas, John Theodore", "degree": "Masters", "year": "1986", "title": "Polycyclic Peroxides and Planar Nitrogens", "advisor": "Schaefer, William P.; Chan, Sunney I.; Dougherty, Dennis A.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04282010-132203527", "creators": [ { "name": { "family": "Fourkas", "given": "John Theodore" }, "id": "Fourkas-John-Theodore", "orcid": "0000-0002-4522-9584", "display_name": "Fourkas, John Theodore" } ], "advisors": [ { "name": { "family": "Schaefer", "given": "William P." }, "id": "Schaefer-W-P", "role": "co-advisor", "display_name": "Schaefer, William P." }, { "name": { "family": "Chan", "given": "Sunney I." }, "id": "Chan-S-I", "orcid": "0000-0002-5348-2723", "role": "advisor", "display_name": "Chan, Sunney I." }, { "name": { "family": "Dougherty", "given": "Dennis A." }, "id": "Dougherty-D-A", "orcid": "0000-0003-1464-2461", "role": "co-advisor", "display_name": "Dougherty, Dennis A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/GMVG-R955", "abstract": "1,6-diaza-3,4,8,9,12,13-hexaoxabicyclo[4.4.4] tetradecane (hexamethylene triperoxide diamine or HMTD) was found, by a single crystal x-ray study, to have planar bridgehead nitrogen atoms. In order to study this planarity, a synthesis was developed for HMTD analogs. Crystals structures were obtained for three of these analogs, 1,6-diaza-3,4,8,9-tetraoxabenzotricyclo[4.4.2]dodec-11-ene (benzene tetramethylene diperoxide diamine or BTDD), 1,8-diaza-10,11,14,15- tetraoxatricyclo[6.4.4.0^(2,7)]hexadecane (cyclohexyl tetramethylene diperoxide diamine or CTDD), and 1,6-diaza3,4,8,9-hexaoxabicyclo[4.4.2]dodecane (hexamethylene diperoxide diamine or HMDD). These structures show that the planarity at the bridgehead nitrogen atoms of HMTD is no coincidence. MM2, a molecular mechanics program, was used to show that this planarity is not expected from simple force considerations. MNDO was used to model the molecule considering molecular orbitals. Finally, nuclear magnetic resonance techniques were used to obtain the energy of activation for inversion of HMTD and to determine the nuclear quadrupole coupling constants of the bridgehead nitrogen atoms at different temperatures, and thus their relative\r\nplanarity.\r\n\r\n" }, { "name": "Lyons, William Lee", "degree": "Masters", "year": "1986", "title": "The Construction and Testing of a Hartley Oscillator for Measuring Temperatures in Free-Floating Objects", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:05112026-225256027", "creators": [ { "name": { "family": "Lyons", "given": "William Lee" }, "id": "Lyons-William-Lee", "display_name": "Lyons, William Lee" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/bnw4-2s92", "abstract": "Several modified Hartley oscillators were constructed from inexpensive,\r\neasily obtained materials and were calibrated for use as wireless temperature\r\nprobes. Three classical experiments involving heat conduction inside solid\r\nspheres were performed to test the oscillators' accuracy. Excellent agreement\r\nwas found between theoretical and oscillator-measured temperature profiles.\r\nFurther experiments were made in which the oscillator was embedded in a\r\nneutrally-buoyant, free-floating solid in order to gain insight into the\r\nThermal history and motion of an object in a confined, heated liquid. These\r\nexperiments demonstrated the device's usefulness as a free-floating\r\ntemperature probe with potential applications in studies of natural convection\r\nand sterilization of enclosed foodstuffs." }, { "name": "Natter, Russell Lawrence", "degree": "Masters", "year": "1986", "title": "Allocations of Computational and Graphical Methods for Separation Processes Calculations and Education", "advisor": "Shair, Fredrick H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05082026-213006452", "creators": [ { "name": { "family": "Natter", "given": "Russell Lawrence" }, "id": "Natter-Russell-Lawrence", "display_name": "Natter, Russell Lawrence" } ], "advisors": [ { "name": { "family": "Shair", "given": "Fredrick H." }, "id": "Shair-F-H", "role": "advisor", "display_name": "Shair, Fredrick H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/mwp6-z058", "abstract": "Two computer programs were developed to teach\r\nseparation processes and to solve related problems. The\r\nfirst, SEPTECH, uses the Fenske-Underwood-Gilliland method\r\nto find stage requirements and column operating parameters\r\nof a multicomponent distillation tower given feed stream\r\ninformation and desired product purities. The second\r\nprogram was designed to achieve specific educational goals.\r\nA robust educational program was developed that was a\r\ngeneral, flexible, fast, understandable, and easy to use\r\ntool for problem solving. This program, MCTHIELE, utilizing\r\nMcCabe-Thiele graphical solution techniques, was used in a\r\nsenior level chemical engineering course and proved to be a\r\nvery successful learning tool." }, { "name": "Thompson, Douglas Kelvin", "degree": "Masters", "year": "1986", "title": "Attempts to Synthesize Cyclic Group 8 Metallaesters", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04262013-145326002", "creators": [ { "name": { "family": "Thompson", "given": "Douglas Kelvin" }, "id": "Thompson-Douglas-Kelvin", "display_name": "Thompson, Douglas Kelvin" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/24t5-yc44", "abstract": "In studying a proposed carbon monoxide reduction scheme\r\nan attempt has been made to synthesize bifunctional group 8 transition metal carbonyl complexes containing intramolecular nucleophiles. The incorporation of alkoxide nucleophiles through cyclopentadienyl ligands was hoped to encourage attack on carbonyl ligands thereby forming cyclic metallaesters. The attempts to synthesize these substituted cyclopentadienyl group 8 transition metal complexes have thus far been unsuccessful.
\r\n" }, { "name": "Ball, Denice", "degree": "Masters", "year": "1985", "title": "Hydrodynamically Modulated Rotating Disk Electrodes", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:04072010-111648791", "creators": [ { "name": { "family": "Ball", "given": "Denice" }, "id": "Ball-Denice", "display_name": "Ball, Denice" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/wg42-fk22", "abstract": "Hydrodynamically modulated rotating disk electrodes (HMRDE) have been studied and utilized with a basic system. Experimental results follow the theoretical predictions fairly closely with a few exceptions. HMRDE is useful in reducing complications due to background currents. The goal of HMRDE in this report is separation of currents due to surface responses from diffusion controlled currents. Some measure of success was obtained by incorporation of Ru(NH_3)^(3+)_6 into a Nafion film. However, the sine wave and square wave modulations are cumbersome and highly inefficient. Once the rotator is interfaced to the IBM 90004 for experimental control and data collection, separation of surface response using HMRDE will be feasible on a practical time scale." }, { "name": "Hannoun, Betty Jane Miller", "degree": "Masters", "year": "1985", "title": "Diffusion Coefficients of Glucose and Ethanol in Cell-Free and Cell-Occupied Calcium Alginate Membranes", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:06272025-211525361", "creators": [ { "name": { "family": "Hannoun", "given": "Betty Jane Miller" }, "id": "Hannoun-Betty-Jane-Miller", "display_name": "Hannoun, Betty Jane Miller" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/9gpk-a215", "abstract": "The diffusivities of glucose and ethanol in cell-free and cell-occupied membranes of calcium alginate were measured in a diffusion cell. The lag time analysis was employed. Diffusivities decreased with increasing alginate concentration and were comparable to those in water for a 2% alginate membrane. Glucose and ethanol concentrations had no effect on the respective diffusion coefficients. The ratio of ethanol diffusivity to glucose diffusivity in 2% and 4% alginate agreed closely to the inverse ratio of the hydrodynamic radii for the two molecules in water indicating that the hydrodynamic theory of diffusion in liquids may be applicable to diffusion in dilute alginate gels. Also the presence of 20% dead yeast cells had no effect on the diffusivities. The data reported can be used to study reaction and diffusion in immobilized cell reactors and cell physiology under immobilized conditions." }, { "name": "Askew, Deidre Ann", "degree": "Masters", "year": "1984", "title": "Electrochemistry of Adsorbed Organic Dye Molecules", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-082538471", "creators": [ { "name": { "family": "Askew", "given": "Deidre Ann" }, "id": "Askew-Deidre-Ann", "display_name": "Askew, Deidre Ann" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/3yjq-7a97", "abstract": "Molecular luminescence has been used to study the mechanism of charge transfer in electrode-bound films and coatings. This sensitive, fast technique enables one to observe occurrences on the electrode surface which could not be observed with conventional electrochemical or spectroelectrochemical methods. In general, electrodes should be excellent quenchers of fluorescence due to energy transfer or electron transfer. We want to examine the mechanism of the surface quenching of the fluorescence. By reproducibly adsorbing a known amount of an organic dye of high quantum yield to the electrode surface, one should be able to determine if electron transfer is a pathway in the quenching mechanism by varying the potential of the electrode. This report describes the electrochemistry of several organic dyes adsorbed on graphite electrodes which could be used for the luminescence studies. Methylene blue adsorption and electrochemistry are studied in detail. The methylene blue system is excellent in terms of adsorption characteristics. Adsorption isotherms are presented which show the range of surface coverage, \u0393, that one can achieve. Methylene blue also has clean reversible electrochemistry to facilitate spectroelectrochemical experiments. However, methylene blue has a small fluorescence quantum yield and short fluorescence lifetime. This may make it a poor choice for luminescence experiments. Several other organic dyes were studied. While their electrochemistry is not as clean as that of methylene blue, their fluorescence quantum yields are much higher." }, { "name": "Handly, Neal Bruce", "degree": "Masters", "year": "1984", "title": "Studies of Regulatory Networks in Cells: Roles of Ions and Small Molecules", "advisor": "Richards, John H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05122010-113308417", "creators": [ { "name": { "family": "Handly", "given": "Neal Bruce" }, "id": "Handly-Neal-Bruce", "display_name": "Handly, Neal Bruce" } ], "advisors": [ { "name": { "family": "Richards", "given": "John H." }, "id": "Richards-J-H", "role": "advisor", "display_name": "Richards, John H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/nwzk-dr03", "abstract": "No abstract." }, { "name": "Le, Anthony Trung", "degree": "Masters", "year": "1984", "title": "Synthesis of the \u03b2-Ketoimides and their Chemical Transformations", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-082952526", "creators": [ { "name": { "family": "Le", "given": "Anthony Trung" }, "id": "Le-Anthony-Trung", "display_name": "Le, Anthony Trung" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/canh-7y33", "abstract": "No abstract." }, { "name": "Turner, Steve Ronald", "degree": "Masters", "year": "1984", "title": "Nitrogen Protecting Groups in the Ester Enolate Claisen Rearrangement of Amino Esters. Synthesis of a Furanomycin Derivative", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-081412450", "creators": [ { "name": { "family": "Turner", "given": "Steve Ronald" }, "id": "Turner-Steve-Ronald", "display_name": "Turner, Steve Ronald" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/x02s-jt53", "abstract": "No abstract." }, { "name": "Anderson, Julie Ann", "degree": "Masters", "year": "1983", "title": "A Total Synthesis of Spiro[Bis(2,3-Diazabicyclo[2.2.1]-Hept-2-Ene-7,7']", "advisor": "Dougherty, Dennis A.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04022010-142818016", "creators": [ { "name": { "family": "Anderson", "given": "Julie Ann" }, "id": "Anderson-Julie-Ann", "display_name": "Anderson, Julie Ann" } ], "advisors": [ { "name": { "family": "Dougherty", "given": "Dennis A." }, "id": "Dougherty-D-A", "orcid": "0000-0003-1464-2461", "role": "advisor", "display_name": "Dougherty, Dennis A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/cqp3-1k14", "abstract": "The total synthesis of spiro[bis(2,3-diazabicyclo[2.2.1]-hept-2-ene)-7,7\u2019] from trans-1,4-dibromo-2-butene was accomplished. One advantage of this synthetic route is that it can be carried out on a relatively large scale. Another advantage is that the synthesis is flexible. With a few minor modifications, one can generate various C\u2089H\u2081\u2082 spiro ring system derivatives." }, { "name": "Goldberg, Aaron Henry", "degree": "Masters", "year": "1983", "title": "Physical and Theoretical Studies of Localized Organic Biradicals", "advisor": "Dougherty, Dennis A.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04292010-114150617", "creators": [ { "name": { "family": "Goldberg", "given": "Aaron Henry" }, "id": "Goldberg-Aaron-Henry", "display_name": "Goldberg, Aaron Henry" } ], "advisors": [ { "name": { "family": "Dougherty", "given": "Dennis A." }, "id": "Dougherty-D-A", "orcid": "0000-0003-1464-2461", "role": "advisor", "display_name": "Dougherty, Dennis A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/w5h0-qg02", "abstract": "Section I. Introduction.\r\n\r\nSection II. Singlet-triplet energy gaps in localized 1,3-biradicals have been investigated using ab initio electronic structure theory. Analysis of both the molecular orbital and generalized valence bond wavefunctions allows one to follow the complex interplay between through-bond and through-space interactions. When the two effects are of similar magnitude, a triplet ground state is possible. However, when one significantly dominates the other, a singlet ground state is expected. Extension of the analysis to other systems and the implications of the results for experimental studies of localized biradicals are discussed.\r\n\r\nSection III. Several unsuccessful attempts to observe the triplet cyclobutane- and cyclohexane-1,3-diyls through low temperature photolysis of the corresponding azo and azoxy compounds are reported. The reasons for these failures are considered together with their implications for the observation of other localized biradicals.\r\n\r\nSection IV. Photolysis of either 7-(2,3-diazabicyclo[2.2.1]hept-2-ene) spirocyclopropane or 7-(2,3-diazabicyclo[2.2.1]hept-2-ene) spiro-5'-bicyclo[2.1.0]pentane in a glassy matrix at 8\u00b0K leads to observation of a triplet ESR spectrum.. Both signals exhibit zero-field splitting parameters which are typical of delocalized systems (|D/hc| = 0.0255 and |E/hci| = 0.003\r\ncm^(-1)). In addition, they are stable at temperatures well in excess of 85\u00b0K. Several possible sources of the two spectra are discussed.\r\n\r\nSection V. A program for the ab initio calculation of zero-field splitting parameters in localized biradicals is developed. The results for several 1,3-biradicals are presented.\r\n" }, { "name": "Heckendorn, Debra Kay", "degree": "Masters", "year": "1983", "title": "Experiments Directed Towards the Total Synthesis of Chlorothricolide", "advisor": "Ireland, Robert E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:11242009-081945536", "creators": [ { "name": { "family": "Heckendorn", "given": "Debra Kay" }, "id": "Heckendorn-Debra-Kay", "display_name": "Heckendorn, Debra Kay" } ], "advisors": [ { "name": { "family": "Ireland", "given": "Robert E." }, "id": "Ireland-R-E", "role": "advisor", "display_name": "Ireland, Robert E." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/q3v3-m204", "abstract": "The attempted synthesis of a differentially protected \"top half\", i, of chlorothricolide is described. The key step necessary for this synthesis was the spirocyclization of the anhydride ii, to prepare the protected tetronic acid iii.\r\n\t\t\t\r\n\t" }, { "name": "Kanne, Robert McNamara", "degree": "Masters", "year": "1983", "title": "Studies of the Enzyme Laccase", "advisor": "Gray, Harry B.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04022010-090654360", "creators": [ { "name": { "family": "Kanne", "given": "Robert McNamara" }, "id": "Kanne-Robert-McNamara", "display_name": "Kanne, Robert McNamara" } ], "advisors": [ { "name": { "family": "Gray", "given": "Harry B." }, "id": "Gray-H-B", "orcid": "0000-0002-7937-7876", "role": "advisor", "display_name": "Gray, Harry B." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/8yyp-a776", "abstract": "Rhus Vernicifera laccase was purified to an \r\nA_(280)/A_(614) ratio of 15.2. A procedure was then used \r\nto selectively remove the Type 2 copper and 70% of \r\nit was removed as judged by EPR. The treated enzyme \r\nshowed decreased absorbance in the 330 nm, region, \r\nwhich is associated with the Type 3 site, The blue \r\ncolor was observed to reversibly bleach on occasion, \r\napparently due to autoreduction of the Type 1 copper. \r\nThe fluorescence of the Type 2 depleted laccase was \r\nincreased 60% over that of the native protein.\r\nSince fluorescence quenching is often associated\r\nwith binding of a metal to a protein site, fluorescence \r\nwas used to monitor the attempted substitution of \r\ncobalt and nickel into the Type 2 site, There is\r\nsome evidence that cobalt can occupy the Type 2 site.\r\n" }, { "name": "Olson, Wendy Ann", "degree": "Masters", "year": "1983", "title": "The Synthesis and Reactivity of New Niobium (V) Polyhydrides", "advisor": "Bercaw, John E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04292010-145411166", "creators": [ { "name": { "family": "Olson", "given": "Wendy Ann" }, "id": "Olson-Wendy-Ann", "display_name": "Olson, Wendy Ann" } ], "advisors": [ { "name": { "family": "Bercaw", "given": "John E." }, "id": "Bercaw-J-E", "role": "advisor", "display_name": "Bercaw, John E." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/e6p9-e788", "abstract": "The synthesis of new niobium polyhydrides by high pressure hydrogenation of Cp*NbMe_4 in the presence of trapping phosphines is reported. The complexes Cp*NbL_2H_4, L=PMe_3, PMe_2Ph, PMe_2Cy, and L_2=bis(dimethylphosphino)ethane, are described. They exchange D_2 into the hydride positions, and react hydridically with methanol and acetone to give alkoxide species. Reactions with CO give reduced metal carbonyl phosphine complexes. All these reactions (except the reaction with methanol) appear to proceed with loss of phosphine as the rate limiting step. Reactions of the hydride species with group VI carbonyls, and with ethylene, are presented. The novel reactivity of Cp*Nb(PMe_2Ph)_2H_4 with H_2 to give Cp*Nb(PMe_2Cy)_2H_4 is discussed." }, { "name": "Runnels, John Hulett", "degree": "Masters", "year": "1983", "title": "Investigation of Coriolis Mixing in Benzene", "advisor": "Marcus, Rudolph A.", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-084636927", "creators": [ { "name": { "family": "Runnels", "given": "John Hulett" }, "id": "Runnels-John-Hulett", "display_name": "Runnels, John Hulett" } ], "advisors": [ { "name": { "family": "Marcus", "given": "Rudolph A." }, "id": "Marcus-R-A", "orcid": "0000-0001-6547-1469", "role": "advisor", "display_name": "Marcus, Rudolph A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/yxqj-6804", "abstract": "An explanation for some recent observations in the \r\nelectronic absorption spectrum of benzene by Schlag and \r\ncoworkers is proposed. Several vibrational lines of the \r\nS_0 to S_1 transition have been studied by these authors with the Doppler\u2014free, two\u2014photon technique developed earlier. The resolution of this technique is so high that individual \u0394 J=0, \u0394 K=0 rotational lines in the Q\u2014branch of a given vibrational transition may be seen in the electronic absorption spectrum. A major progression in the two\u2014photon spectrum is the 14^1_0 1^n_0 progression. It was found that the 14^1_0 1^0_0 and 14^1_0 1^1_0 transitions had well\u2014resolved rotationalstructure, but the 14^1_0 1^2_0 transition had reduced, not well \r\nresolved rotational structure--except for the prominent K=0 \r\nlines for small to medium values of J. This suggested to \r\nus Coriolis mixing. The model presented here utilizes a \r\nsuggestion of Riedle et al.The Coriolis coupling to \r\nneighboring vibrational states is followed by a rapid \r\nradiationless depletion of these states, consistent with \r\nthe decreased fluorescence yield observed by Wunsch et al. \r\nEstimates are made of the density of states of the various \r\nsymmetries; these estimates are then used to estimate the \r\nextent of the relevant Coriolis mixing. The model results \r\nin a large decrease in intensity of non\u2014zero K lines\r\nrelative to the K=0 lines for the 14^1_0 1^2_0 transition, but not for the 14^1_0 1^0_0 and 14^1_0 1^1_0 transitions, in agreement with the experimental observations, making a few assumptions discussed below, but without the use of adjustable parameters. Predictions are then made for the rotational structure of other strong transitions in the two\u2014photon spectrum of benzene.\r\n" }, { "name": "Jones, Melvin O.", "degree": "Masters", "year": "1982", "title": "The Factors Important to Catalysis by Serine Proteases: Structure of Diisopropylfluorophosphate-Inhibited Bovine Trypsinogen Refined at 2.1 \u00c5 Resolution", "advisor": "Stroud, Robert M.", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-075029250", "creators": [ { "name": { "family": "Jones", "given": "Melvin O." }, "id": "Jones-Melvin-O", "display_name": "Jones, Melvin O." } ], "advisors": [ { "name": { "family": "Stroud", "given": "Robert M." }, "id": "Stroud-R-M", "role": "advisor", "display_name": "Stroud, Robert M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/4703-tc82", "abstract": "Crystals of bovine trypsinogen inhibited with diisopropylfluorophosphate (DFP) were grown at pH 7 and x-ray intensity data to 2.1 \u00c5 resolution were collected. The reflections were assigned the phases determined by Kossiakoff (1977) for the isomorphous native trypsinogen structure. Using difference fourier techniques, the resulting protein structure was refined to a residual of 18.2%. As expected, a comparison between (DIP)-trypsinogen and the native trypsinogen structures shows all the structural differences to be in the catalytic site region. However, the structure of the catalytic region was expected to be quite similar to that of DFP-inhibited bovine trypsin at neutral pH, but there exist some marked differences.
\r\n\r\nIn trypsin, one of the isopropyl groups of the inhibitor is analogous to the leaving group of a specific substrate and is hydrolyzed off the inhibitor. In the resulting monoisopropylphosphoryl (MIP)-trypsin, the inhibitor is oriented with a non-esterified phosphoryl oxygen in the oxyanion stabilization site as expected for a tetrahedral intermediate in proteolysis. His 57 N\u03b52 points toward the phosphoryl oxygen at the leaving group site, and is in a position suitable for proton donation to the leaving group.
\r\n\r\nBy contrast, the inhibitor on DIP-trypsinogen remains intact and the presence of electron density at each of the three possible isopropyl locations indicates that the groups of the inhibitor are less specifically oriented. After independent refinement of each of the three possible orientations, the favored orientation was with isopropyl groups near the oxyanion and leaving group sites and the non-esterified phopsphoryl oxygen hydrogen-bonded through two solvent molecules to Ser 214 O. The imidazole ring of His 57 is displaced from its native position at the catalytic site out into the solvent region where it forms hydrogen-bonds to Tyr 94 0 and through a solvent molecule to Ser 214 O. Ser 195 O\u03b3 has moved closer to the position occupied by the His 57 imidazole in native trypsinogen and MIP-trypsin.
\r\n\r\nBoth statistical variation in orientation of the inhibitor and movement of Ser 195 O\u03b3 toward the native imidazole site can be explained by the nonfunctionality of the oxyanion binding site in trypsinogen.
\r\n\r\nThe difference between DIP-Tgen and MIP-trypsin thus suggests both non-productive transition state or substrate binding and stereochemical incompatability between the tetrahedral intermediate and the native imidazole site as possible contributors to the relative inactivity of the proenzyme.
\r\n\r\nConversely, and of more general importance, these results emphasize the importance of exact stereochemical alignment in generating a functional catalytic enzyme.
" }, { "name": "Sekera, Michael H.", "degree": "Masters", "year": "1982", "title": "Cationic Cyclization Involving a Remote Allene Function in the Trifluoroethanolysis of 5,6-heptadien-1-yl p-toluenesulfonate", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03282010-113717103", "creators": [ { "name": { "family": "Sekera", "given": "Michael H." }, "id": "Sekera-Michael-H", "display_name": "Sekera, Michael H." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/dnmp-1s53", "abstract": "In order to determine whether a remote allene function would undergo intramolecular nucleophriftsubstitution, 5,6-heptadien-1-yl p-toluenesulfonate (14) was synthesized and solvolyzed. The major products of the trifluoroethanolysis of 14 were the cyclic trifluoroethyl ethers of 2-methylenecyclohexanol (24) and 1-cyclohexenemethanol (25). The minor product was the direct displacement product, 5,6-heptadien-1-yl 2,2,2-trifluoroethyl ether (23). The cyclic triflurorethyl ethers were also obtained from the solvolysis of two arenesulfonate esters of 24 and 25, the alcohols having been synthesized by an independent route. Kinetic data showed a rate enhancement for 14 relative to its saturated analog." }, { "name": "Soesanto, Tonny", "degree": "Masters", "year": "1982", "title": "The Measurement of Time Dependent Poisson's Ratio", "advisor": "Tschoegl, Nicholas W.", "url": "https://resolver.caltech.edu/CaltechETD:etd-11222004-145049", "creators": [ { "name": { "family": "Soesanto", "given": "Tonny" }, "id": "Soesanto-Tonny", "display_name": "Soesanto, Tonny" } ], "advisors": [ { "name": { "family": "Tschoegl", "given": "Nicholas W." }, "id": "Tschoegl-N-W", "role": "advisor", "display_name": "Tschoegl, Nicholas W." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/YZTZ-MA69", "abstract": "NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document.\r\n\r\nInterest in accurate measurements of the time-dependent Poisson's ratio of polymers arises because it is a component commonly needed in stress analysis and it appears in most theories predicting the behavior of filled materials and composites. Because of the paucity of data and the difficulties in determining [...](t) experimentally, it has been customary in the past to treat [...](t) as a constant. This is unsatisfactory theoretically and inadequate for accurate work.\r\n\r\nAn apparatus has been constructed that enables us to measure tensile relaxation modulus, E(t), and time-dependent Poisson's ratio, [...](t), simultaneously on the same specimen under the same experimental condition. The apparatus, which contains several novel features, is essentially in working condition. Experiments will be made on a series of selected polymers.\r\n\r\nWe hope to be able to determine the bulk relaxation modulus, K(t), and the shear relaxation modulus, G(t), from measurements of E(t) and [...](t). A method for solving the appropriate convolution integrals to determine K(t) and G(t) is already available. It would be desirable to compare the calculated G(t) and K(t) with direct measurements. The latter are very difficult. Direct measurements of G(t) will be made in a torsional relaxometer on the same specimen but not under identical conditions. Nevertheless, these data will be useful as a check on our measurements and our method of calculation.\r\n\r\nThis work will allow a comparison to be made between shear and bulk relaxation via the spectral functions. The measurements will ultimately form the basis for the development of a theory of bulk relaxation in polymeric materials." }, { "name": "Howard, Thomas R.", "degree": "Masters", "year": "1981", "title": "Reactions of an Aluminum Stabilized Titanium Alkylidene", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03292010-081003488", "creators": [ { "name": { "family": "Howard", "given": "Thomas R." }, "id": "Howard-Thomas-R", "display_name": "Howard, Thomas R." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/48f6-5a82", "abstract": "[Introduction] In recent years there has been a great deal of interest in organometallic alkylidene complexes as they are one of the postulated intermediates for the currently accepted mechanism of metathesis. Our interest was drawn to an aluminum stabilized titanium alkylidene because it had been reported to catalyze metathesis and to demonstrateother novel reactivity. This paper reports our results in the study of the chemistry of this complex." }, { "name": "Auburn, Pamela Rae", "degree": "Masters", "year": "1980", "title": "Synthesis, Characterization, and Reactivity of Permethyltitanocene Monoethylene Complex", "advisor": "Bercaw, John E.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04022010-140317486", "creators": [ { "name": { "family": "Auburn", "given": "Pamela Rae" }, "id": "Auburn-Pamela-Rae", "display_name": "Auburn, Pamela Rae" } ], "advisors": [ { "name": { "family": "Bercaw", "given": "John E." }, "id": "Bercaw-J-E", "role": "advisor", "display_name": "Bercaw, John E." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/q8e0-k091", "abstract": "No abstract." }, { "name": "Gerwer, Alexander Sherwin", "degree": "Masters", "year": "1980", "title": "A Discrete Basis Set Technique for Calculating Photoionization Cross Sections Utilizing Moment Theory", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:05042010-123305037", "creators": [ { "name": { "family": "Gerwer", "given": "Alexander Sherwin" }, "id": "Gerwer-Alexander-Sherwin", "display_name": "Gerwer, Alexander Sherwin" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/E1ZA-6224", "abstract": "No abstract." }, { "name": "Grunthaner, Paula Jean", "degree": "Masters", "year": "1980", "title": "I. Isolation of LAC Operator DNA. II. XPS Investigation of the GaAs/Native Oxide and Si/Metal Interfaces", "advisor": "Dickerson, Richard E.; Mayer, James Walter", "url": "https://resolver.caltech.edu/CaltechTHESIS:07142025-221617617", "creators": [ { "name": { "family": "Grunthaner", "given": "Paula Jean" }, "id": "Grunthaner-Paula-Jean", "display_name": "Grunthaner, Paula Jean" } ], "advisors": [ { "name": { "family": "Dickerson", "given": "Richard E." }, "id": "Dickerson-Richard-E", "role": "advisor", "display_name": "Dickerson, Richard E." }, { "name": { "family": "Mayer", "given": "James Walter" }, "id": "Mayer-J-W", "role": "advisor", "display_name": "Mayer, James Walter" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/7tzy-bv05", "abstract": "Chapter I
\r\n\r\nA procedure is presented for the large scale isolation of cloned\r\n29 base-pair lac operator DNA from plasmid DNA. The methodology is\r\ngeneral and may be used to isolate other cloned DNA fragments as well.
\r\n\r\nInitial ultraviolet difference experiments with lac repressor\r\nprotein are also presented. Solvent perturbation is used to locate\r\nthe tyrosine and tryptophan residues.
\r\n\r\nChapter II
\r\n\r\nThe chemical structure of the thin native oxide of GaAs (30 - 40 \u00c5)\r\nhas been investigated using x-ray photoelectron spectroscopy. Both\r\nwet chemical and argon ion bombardment techniques have been used to\r\ndepth profile the oxide structure. The composition of the oxide is\r\nfound to be quite complex and the distribution of the various species\r\nas a function of oxide thickness is discussed.
\r\n\r\nA Fouries transform data reduction technique based on linear\r\nprediction has been used to develop possible explanations for the\r\nexperimentally observed chemical shifts and composition layers.\r\nEvidence is found for the presence of As2O3, Ga2O3, and the mixed\r\noxide GaAsO4.
\r\n\r\nChapter III
\r\n\r\nA systematic investigation of the bonding properties of selected\r\ntransition metal silicides on single crystal Si substrates is proposed.\r\n4He+ back scattering, XPS, and x-ray excited AES will be used to\r\ncharacterize both the bulk and interfacial bonding properties. Initial\r\nexperiments are presented to demonstrate the feasibility of the approach.
" }, { "name": "Neilson, Paul Vincent", "degree": "Masters", "year": "1980", "title": "Electrochemistry of Polymer-Metal Complexes", "advisor": "Anson, Fred C.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04052010-111723098", "creators": [ { "name": { "family": "Neilson", "given": "Paul Vincent" }, "id": "Neilson-Paul-Vincent", "display_name": "Neilson, Paul Vincent" } ], "advisors": [ { "name": { "family": "Anson", "given": "Fred C." }, "id": "Anson-F-C", "role": "advisor", "display_name": "Anson, Fred C." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/HS95-4691", "abstract": "Polymeric ligands, Polyethylenimine (PEI) and Chitosan, were studied for possible applications in the modification of electrode surfaces in relation to the three main goals:
\r\n\r\n1. metal ion scavenging
\r\n2. to find a system which catalyzes O2 reduction
\r\n3. understanding of electron transfer in polymer-metal films.
Part I:
\r\nThe literature synthesis, with some modifications, of tricyclo[ 4, 1, 0, 03,7]heptane was undertaken. While considerable difficulty was encountered in the final reaction involving a sodium borohydride reduction, far more successful results were obtained when lithium aluminum hydride was used instead as the reducing agent. The hydrocarbon can be stereospecifically deuterated at various points in the reaction sequence and once labeled, can be pyrolyzed and its products studied to determine the extent of orbital symmetry restrictions on the pyrolytic rearrangement process.
Part II:
\r\nIn efforts to produce the mono- and diadducts of dichloro- and dibromocarbene to cyclopentadiene, it was found that the respective 6-halofulvenes were being produced instead. Depending upon the conditions used, varying amounts of halobenzene and 1, 1-dihalo-2, 2- dimethylcyclopropane could be produced as other major reaction products. The fulvenes were obtained in best yield using haloform as the dihalocarbene precursor and potassium tert-butoxide as the base. Ethyl trichloroacetate and phenyl (bromodichloromethyl) mercury were also used with various bases to generate dichlorocarbene, but these methods were unsuccessful in producing the 6-chlorofulvene.
The present work attempts to obtain a mathematical model for generation and dispersion of photochemical smog. A simplified kinetic model which is proposed by Friedlander and Seinfeld (1969), is presented for the photochemical smog reactions. To take into account the effect of atmospheric mixing processes on the chemical reactions, the Lagrangian similarity hypothesis for the diffusion of non-reactive components is extended to reacting species. The concept of a variable volume batch reactor model (VVBR) is applied in the study of the formation of photochemical smog. The critical value, [h/bu*]cr. where h is the source height, b constant and u* friction velocity, for the onset of photochemical smog is found.
\r\n\r\nCalculations based on the simplified kinetic model and the applications of the Lagrangian similarity hypothesis are given for a nonlinear, second order chemical reaction. Finally, determination of the probability density function of the pollutant is given for the non-reacting case.
" }, { "name": "Lee, Chi-Yu Gregory", "degree": "Masters", "year": "1971", "title": "The Tautomeric Exchange of Nucleic Acid Bases", "advisor": "Chan, Sunney I.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05042010-094013118", "creators": [ { "name": { "family": "Lee", "given": "Chi-Yu Gregory" }, "id": "Lee-Chi-Yu-Gregory", "display_name": "Lee, Chi-Yu Gregory" } ], "advisors": [ { "name": { "family": "Chan", "given": "Sunney I." }, "id": "Chan-S-I", "role": "advisor", "display_name": "Chan, Sunney I." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/TDW7-S132", "abstract": "[Part 1]. For a series of PMR studies of cytidine and related compounds in D\u2082O solution at various pD, it was observed that the H\u2085 resonances of cytosine base are broad in some of these compounds at pD 4-7, while those of H\u2086 are not. We proposed that there is chemical exchange between two tautomeric forms of cytosine base to give rise to broadening of spectra. This chemical exchange was found to be catalyzed by both solvent (D\u2082O)and hydroxyl (OD\u207b) ion present in solution. The observation of sharp resonances in certain cytidine derivatives having only one possible \r\ntautomeric structure supports this proposal. Temperature study of H\u2085 resonances at different pD was used to investigate the kinetics of this exchange reaction. The percentage of its minor tautomer was estimated as 10 \u00b1 2% in neutral aqueous solution and its life time is about 10\u207b\u00b3 sec at room temperature. The activation energy of this tautomeric exchange is 7.5 \u00b1 0. 5 kcal/mole. for D\u2082O catalysis and 2.5 \u00b1 0.5 kcal/mole for OD\u207b catalysis. The relation between tautomeric exchange of nucleic acids and genetic mutation is also discussed.
\r\n\r\n[Part 2]. From the PMR study of guanosine and its related compounds at different pD, temperature and concentrations, it was observed that H\u2088 resonances of guanine base in some of these compounds are unusually broad over a wide pD range (from 2 to 8) in aqueous solutions. This phenomenon is explained in terms of the effects of base pairing, stacking and tautomeric exchange between the 1 and 6 positions of guanine base. The observation of sharp resonance of H\u2088 of\r\n1-methyl guanosine having only one possible tautomeric structure supports that there exists minor tautomer of this base. This tautomeric exchange is catalyzed either by solvent (D\u2082O), base (OD\u207b) or pairing of base. The percentage of minor tautomer and the activation energy of the exchange are also estimated from the kinetic analysis.
" }, { "name": "O'Brien, Edward Francis", "degree": "Masters", "year": "1971", "title": "Studies on the Microscopic Motion of a Diatomic in a Monatomic Solvent", "advisor": "Robinson, G. Wilse", "url": "https://resolver.caltech.edu/CaltechTHESIS:05112010-155239731", "creators": [ { "name": { "family": "O'Brien", "given": "Edward Francis" }, "id": "O'Brien-Edward-Francis", "display_name": "O'Brien, Edward Francis" } ], "advisors": [ { "name": { "family": "Robinson", "given": "G. Wilse" }, "id": "Robinson-G-W", "role": "advisor", "display_name": "Robinson, G. Wilse" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/JH9Y-QR36", "abstract": "The microscopic motion of a diatomic in a monatomic solvent has been studied using the molecular dynamics method and a model of Lennard-Jones spheres for the monatomics and two such spheres joined by a rigid bond for the diatomic. Data were generated by computer for three systems, each at the same density but varying in temperature. From these data autocorrelation functions were calculated for the following random quantities of the motion of the diatomic: orientation of the diatomic, velocity of its center of mass angular velocity and momentum, mean square displacement of its center of mass and the forces on the diatomic bond. Infrared and Raman band shapes and NMR relaxation times were determined from the above correlation functions.\r\n\r\nThe decay times of the correlation functions were found to be in the range of 0.25 to 2.5 x 10^(-12) sec. The band shapes were symmetrical and their bandwidth change reflects the change in inhonaogeneous broadening with respect to temperature. The NMR, relaxation times also behave correctly with respect to temperature and indicate which of the relaxation mechanisms studied is dominant.\r\n\r\nFurther studies are proposed to determine the reason for the discrepancies between the above calculated quantities and those quantities obtained from experimental data.\r\n" }, { "name": "Strickland, Alan Douglas", "degree": "Masters", "year": "1971", "title": "Studies on Transition Metal Porphines and Phthalocyanines", "advisor": "Gray, Harry B.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12112009-150339244", "creators": [ { "name": { "family": "Strickland", "given": "Alan Douglas" }, "id": "Strickland-Alan-Douglas", "display_name": "Strickland, Alan Douglas" } ], "advisors": [ { "name": { "family": "Gray", "given": "Harry B." }, "id": "Gray-H-B", "orcid": "0000-0002-7937-7876", "role": "advisor", "display_name": "Gray, Harry B." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/SYPY-BS46", "abstract": "Model systems for heme were constructed using three different compounds. The tetrasulfophthalocyanine transition metal derivatives were studied and rejected due to problems with the purification procedure. Transition metal derivatives of tetrapyridyl porphine were studied and rejected due to problems in the synthesis and low concentrations of the chemical in solution. Finally, the transition metal derivatives of tetraphenyl porphine were studied and spectral data were obtained.\r\n\r\nThe spectral data indicate that Fe(II)TPP is stable in the presence of oxygen. A photochemical reaction does occur, however, which appears to change the Fe(II)TPP to Fe(III)TPP.\r\n\r\nOther facts were also found. The ZnTPP is found to undergo a photochemical reaction similar to the one for Fe(II)TPP. The MnTPP appears to have already changed oxidation state upon synthesis.\r\n\r\nThe data suggest that TPP is a possible system for studying the interaction of heme and oxygen. The TPyP system might be even better if the problems with synthesis could be solved since its water solubility should solve the problem due to a low concentration.\r\n" }, { "name": "Surratt, Grover Timothy", "degree": "Masters", "year": "1971", "title": "The Minimum Kinetic Energy Orbital and the Band Structure of Sodium", "advisor": "Goddard, William A., III", "url": "https://resolver.caltech.edu/CaltechTHESIS:04292010-111816149", "creators": [ { "name": { "family": "Surratt", "given": "Grover Timothy" }, "id": "Surratt-Grover-Timothy", "display_name": "Surratt, Grover Timothy" } ], "advisors": [ { "name": { "family": "Goddard", "given": "William A., III" }, "id": "Goddard-W-A-III", "orcid": "0000-0003-0097-5716", "role": "advisor", "display_name": "Goddard, William A., III" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/2665-JE74", "abstract": "For calculations on molecules and solids it has proven \r\nuseful to replace the various core electrons with a pseudo-potential. The most common method for doing this, that of \r\nPhillips andKleinman, suffers from the disadvantage that\r\nthe pseudopotential obtained is not unique. It has previously \r\nbeen shown, however, th t the non-uniqueness problem can be \r\nresolved by the use of ab-initio GI orbitals as the basis\r\nfor the potential. Such potentials have proven quite \r\nsatisfactory in replacing the core electrons in molecular and \r\nsolid-state calculations. Unfortunately, systems of ten or \r\nmore electrons are not accessible to GI, so that the approach \r\ncannot be used for sodium, for example.\r\n\r\n We have examined the GI orbitals and effective potentials \r\nfor Li, Be+, B++ and compared these orbitals and potentials \r\nwith those obtained from the usual Hartree-Fock formalism,\r\nbut employing an extra condition on the orbitals to ensure \r\nuniqueness. It was found that a condition suggested (but \r\napparently never tried) by Cohen and Heine, that the Hartree-Fock core orbitals be allowed to mix with the valence\r\norbital in such a way as to minimize the kinetic energy, \r\nproduced orbitals and potentials nearly identical to those \r\nfrom the GI method.\r\n\r\n We then employed this method to obtain local potentials \r\nfor the ^2S, ^2P and ^2D states of sodium.. These potentials \r\nwere found to reproduce the spectrum of sodium quite well.\r\nThese potentials were then used to study the energy levels \r\nof sodium metal at the high symmetry points in the Brillouin \r\nzone, employing the GI band structure formalism.\r\n" }, { "name": "Wyatt, Robert Howard", "degree": "Masters", "year": "1971", "title": "Acidity, Basicity, and Ion-Molecule Reactions of Arsine in the Gas Phase by Ion Cyclotron Resonance Spectroscopy", "advisor": "Beauchamp, Jesse L.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04082010-073342301", "creators": [ { "name": { "family": "Wyatt", "given": "Robert Howard" }, "id": "Wyatt-Robert-Howard", "display_name": "Wyatt, Robert Howard" } ], "advisors": [ { "name": { "family": "Beauchamp", "given": "Jesse L." }, "id": "Beauchamp-J-L", "role": "advisor", "display_name": "Beauchamp, Jesse L." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/CNW1-W685", "abstract": "The ion-molecule reactions of arsine, both pure and in binary mixtures with several other molecules, have been investigated by ion cyclotron resonance spectroscopy. Reaction pathways, product distributions, and rate constants have been determined for the ion-molecule reactions for both positive and, to a lesser extent, negative ions. Arsine fragment ions condense with neutral AsH_3 to generate product ions containing two and, on further reaction, three atoms of arsenic. In the process of condensation, one or two molecules of H_2 are expelled. The formation of AsH_4^+ occurs from AsH_3^+ which does not undergo condensation reactions to any significant extent. Where possible, thermochemical data have been determined, including the gas phase acidity, PA(AsH_2^-) = 356 \u00b1 6 kcal/mole, and basicity, PA(AsH_3) = 175 \u00b1 5 kcal/mole, of AsH_3. Observation of gas phase nucleophilic displacement reactions involving AsH_3 as a nucleophile have allowed limits to be placed on the basicity of AsH_3 toward a soft acid, CH_3^+. The implications of these results are discussed and the ion-molecule reactions of AsH_3 are compared with those of other hydrides.\r\n" }, { "name": "Bell, Karl Ammon", "degree": "Masters", "year": "1970", "title": "Theory of Particle Deposition by Inertial Forces at Bifurcations in the Human Respiratory Tract", "advisor": "Lees, Lester; Friedlander, Sheldon K.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05172018-084339801", "creators": [ { "name": { "family": "Bell", "given": "Karl Ammon" }, "id": "Bell-Karl-Ammon", "display_name": "Bell, Karl Ammon" } ], "advisors": [ { "name": { "family": "Lees", "given": "Lester" }, "id": "Lees-L", "role": "advisor", "display_name": "Lees, Lester" }, { "name": { "family": "Friedlander", "given": "Sheldon K." }, "id": "Friedlander-S-K", "role": "advisor", "display_name": "Friedlander, Sheldon K." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/XVNX-TN65", "abstract": "The prediction of lung disease development in man from\r\naerosol particles and the medical justification for subsequent \r\ncontrol of particulate atmospheric pollutants requires specific\r\nknowledge of the rate and location of the aerosol deposition\r\nin the lungs. A theoretical development is presented to\r\nnumerically predict the rate and location of aerosol deposition\r\nby impaction at the wedge walls in a model of a lung bifurcation.\r\nTwo limiting flow cases, steady potential flow and steady\r\nlaminar boundary layer flow, are analyzed and found to\r\nrepresent upper and lower bounds of limited experimental deposition\r\ndata for one-micron particle obtained from a lung apparatus\r\nsimulating normal inhalations.
\r\n\r\nNumerical deposition results for 20, 10, 5, 4, 3, 2,\r\nand 1 micron particles in steady potential flow show\r\ndeposition fluxes to be functions of Stokes number and also\r\nthe local air velocity distribution along the wedge. Boundary\r\nlayer deposition results for the same particle are found to\r\ncorrespond to the first few data points of the steady potential\r\ncase, however no boundary layer deposition occurs beyond a\r\nfew particle diameters along the wedge.
" }, { "name": "Frank, Robert", "degree": "Masters", "year": "1970", "title": "Theoretical correlation of the geometry and magnetic hyperfine splittings of the methyl radical", "advisor": "Goddard, William A., III", "url": "https://resolver.caltech.edu/CaltechTHESIS:04302010-075156671", "creators": [ { "name": { "family": "Frank", "given": "Robert" }, "id": "Frank-R", "display_name": "Frank, Robert" } ], "advisors": [ { "name": { "family": "Goddard", "given": "William A., III" }, "id": "Goddard-W-A-III", "role": "advisor", "display_name": "Goddard, William A., III" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/5YF2-J383", "abstract": "Spin densities at carbon and hydrogen are calculated at several out of plane angles of the methyl radical. Comparison with temperature dependent ESR studies indicate that the GF method describes the variation adequately while Hartree-Fock, Unrestricted Hartree-Fock, and Valence-Bond treatments do not." }, { "name": "Hudson, Bruce Samuel", "degree": "Masters", "year": "1969", "title": "Studies of Circular and Catenated Circular DNA", "advisor": "Vinograd, Jerome Rubin", "url": "https://resolver.caltech.edu/CaltechTHESIS:05072010-114048109", "creators": [ { "name": { "family": "Hudson", "given": "Bruce Samuel" }, "id": "Hudson-Bruce-Samuel", "display_name": "Hudson, Bruce Samuel" } ], "advisors": [ { "name": { "family": "Vinograd", "given": "Jerome Rubin" }, "id": "Vinograd-J-R", "role": "advisor", "display_name": "Vinograd, Jerome Rubin" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/1JDD-AM72", "abstract": "No abstract." }, { "name": "Hudson, Mary Suzanne Speck", "degree": "Masters", "year": "1969", "title": "Applications of a Method for the Analyses of Many-Electron Wavefunctions", "advisor": "McKoy, Basil Vincent", "url": "https://resolver.caltech.edu/CaltechTHESIS:05032010-093742868", "creators": [ { "name": { "family": "Hudson", "given": "Mary Suzanne Speck" }, "id": "Hudson-Mary-Suzanne-Speck", "display_name": "Hudson, Mary Suzanne Speck" } ], "advisors": [ { "name": { "family": "McKoy", "given": "Basil Vincent" }, "id": "McKoy-B-V", "role": "advisor", "display_name": "McKoy, Basil Vincent" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/99MP-BR64", "abstract": "We show how the method of successive partial orthogonalizations can be used to obtain approximate Hartree-Fock (HF) pair functions directly from the hydrogenic pair functions. The method is more practical than accurate but with the explicit Z-dependence of the bar -nuclei pair functions just eleven such pair functions are needed to obtain an approximate HF pair function by this method for any pair of orbitals in any first row atom. We use the same method of analysis to extract HF orbitals directly from suitable trial functions for the He-He system at several internuclear distances and and also for the auto-ionizing 2s^2 2p^2 states of helium. This approach avoids a separate variational calculation for the HF wave function and furthermore it provides approximate HF pair functions for these auto-ionizing states." }, { "name": "Rathjen, Nancy Katherine", "degree": "Masters", "year": "1969", "title": "An Investigation of the System Cr(III)/Cr(II) by Digital Polarography, at Different Cr(III) Concentrations, at Varying pH, and in Different Supporting Electrolytes", "advisor": "Anson, Fred C.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05042010-123622070", "creators": [ { "name": { "family": "Rathjen", "given": "Nancy Katherine" }, "id": "Rathjen-Nancy-Katherine", "display_name": "Rathjen, Nancy Katherine" } ], "advisors": [ { "name": { "family": "Anson", "given": "Fred C." }, "id": "Anson-F-C", "role": "advisor", "display_name": "Anson, Fred C." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/N5V3-H153", "abstract": "One of the implications of Marcus theory of electron transfer is that d, the electrochemical transfer coefficient, would not be constant, but would be a function of potential. Recent work has tended to confirm this implication.\r\n\r\nTo examine this possible potential-dependence d, the system Cr(III)/Cr(II) was investigated by digital polarography, at different Cr(III) concentrations, at varying pH, and in different supporting electrolytes. Most of the resulting rate data do suggest a potential-dependence of d.\r\n\r\nApparent heats of activation were obtained for three of the supporting electrolytes investigated, and from these a calculation was made of the magnitude of the potential-dependence predicted by Marcus theory. There was little correlation between the magnitude of the potential-dependence predicted by Marcus theory, and that actually found.\r\n" }, { "name": "Komai, Ralph Yutaka", "degree": "Masters", "year": "1967", "title": "A Study of the Effect of Viscosity on the Resolution of Bands in the Preparative Ultracentrifuge", "advisor": "Vinograd, Jerome Rubin", "url": "https://resolver.caltech.edu/CaltechTHESIS:05072010-090546085", "creators": [ { "name": { "family": "Komai", "given": "Ralph Yutaka" }, "id": "Komai-Ralph-Yutaka", "display_name": "Komai, Ralph Yutaka" } ], "advisors": [ { "name": { "family": "Vinograd", "given": "Jerome Rubin" }, "id": "Vinograd-J-R", "role": "advisor", "display_name": "Vinograd, Jerome Rubin" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/570A-N634", "abstract": "Band velocity experiments in the preparative ultracentrifuge are usually performed in a linear density gradient established by mixing a 5% and a 20% sucrose solution. This stabilizing density gradient introduces a significant viscosity gradient which in turn may effect the resolving power of the sedimentation velocity experiment. The fast components travel on the average through more viscous solutions than do the slow components.\r\n\r\nIn this investigation the effect of viscosity gradients \r\nwas examined by experiments in which density stability was \r\nachieved by using a cesium chloride density gradient and the viscosity was independently controlled by introducing a uniform sucrose concentration or a positive or negative sucrose gradient in the cesium chloride gradient.\r\n\r\nExperiments performed with a mixture of tritiated thymidine labeled polyoma DNA components I, II, and III showed \r\nthat the separation of band maxima increased as the direction of the viscosity gradient was changed from positive to zero to negative with respect to field. On the other hand the band widths increased in the same order. The resolution in terms of the separation between the bands divided by the sum of the band widths was clearly lowest with the negative viscosity gradient and was approximately the same for the positive and zero viscosity gradients." }, { "name": "Smith, Stephen Charles", "degree": "Masters", "year": "1967", "title": "Analysis and Interpretation of the Fluorine N.M.R. Spectrum of 1,3-Dimethoxy-1,1,2,3,3-Pentafluoropropane", "advisor": "Roberts, John D.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04072010-114932724", "creators": [ { "name": { "family": "Smith", "given": "Stephen Charles" }, "id": "Smith-Stephen-Charles", "display_name": "Smith, Stephen Charles" } ], "advisors": [ { "name": { "family": "Roberts", "given": "John D." }, "id": "Roberts-J-D", "role": "advisor", "display_name": "Roberts, John D." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/0Z2N-CM78", "abstract": "A variety of physical techniques including infrared, micro\u00adwave and Raman spectrocopies and dipole measurements have been used to study conformational preferences and restricted rotation in aliphatic compounds. N. m. r. spectra are now of recognized utility in studies of this sort (1, 2, 3, 4).
\r\n\r\nThis thesis is concerned with a study of the n. m. r. spectrum of 1, 3-dimethoxy-1, 1, 2, 3, 3-pentafluoropropane (I) and presents information about the propensities for conformational preferences in alkyl fluoroalkyl ethers.
" }, { "name": "Steadman, Vivian Louise", "degree": "Masters", "year": "1967", "title": "Some Factors Which Affect the Spin Densitites of Protons, with Particular Emphasis on the \u03b2-Protons of Cyclobutenyl", "advisor": "McLachlan, Andrew D.; McKoy, Basil Vincent", "url": "https://resolver.caltech.edu/CaltechTHESIS:05072010-160004325", "creators": [ { "name": { "family": "Steadman", "given": "Vivian Louise" }, "id": "Steadman-Vivian-Louise", "display_name": "Steadman, Vivian Louise" } ], "advisors": [ { "name": { "family": "McLachlan", "given": "Andrew D." }, "id": "McLachlan-A-D", "role": "advisor", "display_name": "McLachlan, Andrew D." }, { "name": { "family": "McKoy", "given": "Basil Vincent" }, "id": "McKoy-B-V", "role": "advisor", "display_name": "McKoy, Basil Vincent" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/6S0F-1650", "abstract": "Both first-order and variational valence bond calculations were made to estimate the ESR hyperfine splittings of the \u03b2-protons of cyclobutenyl. The ESR spectrum of the radical has not been obtained; but on the basis of these calculations, it is anticipated that the \u03b2-proton splittings will be large and in the range 42g to 101g. The first-order results indicate considerably larger splittings than the variational calculation; this situation was shown to be in marked contrast with another valence bond calculation on a free radical containing \u03b2-protons. Possible inequality in the \u03b2-proton splittings of cyclobutenyl at low temperatures was also discussed.\r\n\r\nThe dependence of the spin densities of \u03b2-protons on \u03c0-electron excitation energies (in appropriate free radicals) was discovered and was shown to reduce the size of the \u03b2-proton hyperfine splittings. The agreement with experiment was satisfactory.\r\n\r\nThe transformation between the vector-coupling states for an eight electron system and its canonical states was obtained. The canonical states were found to be especially amenable to computer computations, involving the non-overlap, empirical valence bond theory.\r\n\r\nThe reasons for the suitability of the use of vector-coupling functions in configuration interaction in the valence bond theory were discussed. A case was presented in which it appeared desirable to distribute the antisymmetrical spatial components of the ground-state\r\nwave function somewhat differently in space than that of the symmetrical spatial components.\r\n\r\nAn anomaly in the ESR spectra of irradiated benzene was deduced from theoretical considerations." }, { "name": "Brueckner, David Armstrong", "degree": "Masters", "year": "1966", "title": "Studies in enzyme crystallography", "advisor": "Niemann, Carl G.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05062010-111323235", "creators": [ { "name": { "family": "Brueckner", "given": "David Armstrong" }, "id": "Brueckner-D-A", "display_name": "Brueckner, David Armstrong" } ], "advisors": [ { "name": { "family": "Niemann", "given": "Carl G." }, "id": "Niemann-C-G", "role": "advisor", "display_name": "Niemann, Carl G." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/W06N-8494", "abstract": "This thesis presents X-ray crystallographic research on chymotrypsin and lysozyme. Seven crystal types of chymotrypsin were identified -- five for the first time. The seven crystal types appear to be different packings of two conformations of the same molecule.\r\n\r\nOne crystal type of lysozyme was studied. From Patterson projections of crystals diffused with PtI_6^= ions, the x, y, and z coordinates for these ions were determined. After one least squares refinement of these coordinates, the agreement factor between calculated and observed contributions of the PtI_6^= ions was 0.34 for 108 hkO and hOl reflections. Using these coordinates, an hkO and an hOl Fourier projection were prepared.\r\n\r\nX and y coordinates for the heavy atoms in lysozyme crystals diffused with UO_2^(++) ions, WO_4^= ions, HgI_4^= ions, HgCl_2, ThCl_4, and p-ClHg\u0444SO_3H were determined from Patterson and Fourier projections.\r\n" }, { "name": "Roth, Dana Lincoln", "degree": "Masters", "year": "1965", "title": "Charge-Transfer Association in Enzyme Inhibition", "advisor": "Niemann, Carl G.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05052010-095701928", "creators": [ { "name": { "family": "Roth", "given": "Dana Lincoln" }, "id": "Roth-Dana-Lincoln", "display_name": "Roth, Dana Lincoln" } ], "advisors": [ { "name": { "family": "Niemann", "given": "Carl G." }, "id": "Niemann-C-G", "role": "advisor", "display_name": "Niemann, Carl G." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/DPPB-6X75", "abstract": "Attempts to determine if charge-transfer bonding forces are involved in enzyme inhibition by gas chromatographic and spectral methods were, in general, unsuccessful.
\r\n\r\nDirect spectral evidence of formation of the \u03b2-naphthoquino-linium cation in the presence of the enzyme, \u03b1-chymotrypsin, has been shown.
" }, { "name": "Grocki, John James", "degree": "Masters", "year": "1964", "title": "Nuclear Magnetic Resonance Studies of Solvent Effect on the Molecular Structure of Some Aryl and Alkyl Ethers", "advisor": "Roberts, John D.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04292010-141753551", "creators": [ { "name": { "family": "Grocki", "given": "John James" }, "id": "Grocki-John-James", "display_name": "Grocki, John James" } ], "advisors": [ { "name": { "family": "Roberts", "given": "John D." }, "id": "Roberts-J-D", "role": "advisor", "display_name": "Roberts, John D." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/4FAK-TX66", "abstract": "The nuclear magnetic resonance spectra of several substituted benzyl ethers containing a center of asymmetry reveals that in certain solvents the methylene protons of the ether are magnetically nonequivalent. Further investigation shows that the magnitude of this effect is related to the dielectric constant of the solvent.\r\n\r\nFrom this information a structure for the molecule in solution is postulated, and the observed magnetic nonequivalence of the protons is explained on the basis of steric and electronic effects.\r\n" }, { "name": "Shah, Usha", "degree": "Masters", "year": "1964", "title": "\u03b1-Carbonium Ion Stabilization in Derivatives of Cyclopentadienylmanganese Tricarbonyl", "advisor": "Richards, John H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05032010-131343121", "creators": [ { "name": { "family": "Shah", "given": "Usha" }, "id": "Shah-Usha", "display_name": "Shah, Usha" } ], "advisors": [ { "name": { "family": "Richards", "given": "John H." }, "id": "Richards-J-H", "role": "advisor", "display_name": "Richards, John H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/GQ3E-6784", "abstract": "A study has been made of the solvolyses of some acetoxy and trifluoroacetoxy compounds of cyclopentadienylmanganese tricarbonyl and of benzene. Also, a study of some addition reactions to the double bond of vinyl cyclopentadienylmanganese tricarbonyl has been made. Both studies show that an \u03b1-cyclopentadienylmanganese tricarbonyl carbonium ion is less stable than an \u03b1-ferrocenylcarbonium ion, but more stable than an \r\n\u03b1-phenylcarbonium ion.\r\n" }, { "name": "Patel, Dinshaw Jehangir", "degree": "Masters", "year": "1963", "title": "Nuclear Magnetic Resonance Spectroscopy Cyclopropane Derivatives", "advisor": "Roberts, John D.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04302010-094941787", "creators": [ { "name": { "family": "Patel", "given": "Dinshaw Jehangir" }, "id": "Patel-Dinshaw-Jehangir", "display_name": "Patel, Dinshaw Jehangir" } ], "advisors": [ { "name": { "family": "Roberts", "given": "John D." }, "id": "Roberts-J-D", "role": "advisor", "display_name": "Roberts, John D." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/MXFQ-9281", "abstract": "Chemical shifts and coupling constants have been determined from the analysis of proton nuclear magnetic resonance spectra for a series of cyclopropane derivatives . The geminal and vicinal cyclopropyl couplings have opposite signs. Additional ^(13)C-H coupling constants have been obtained for cyclopropanes which support the conclusion that the hybridization in cyclopropanes is close to sp^2. The chemical shifts for several cyclopropanes seem consistent with a ring-current effect." }, { "name": "Foran, Bernard", "degree": "Masters", "year": "1962", "title": "Some Optical Spectra Studies of the Rare Earth Atom Samarium in Inert Gas Matrices at 4.2\u00b0K", "advisor": "Robinson, G. Wilse", "url": "https://resolver.caltech.edu/CaltechTHESIS:05072010-114413285", "creators": [ { "name": { "family": "Foran", "given": "Bernard" }, "id": "Foran-Bernard", "display_name": "Foran, Bernard" } ], "advisors": [ { "name": { "family": "Robinson", "given": "G. Wilse" }, "id": "Robinson-G-W", "role": "advisor", "display_name": "Robinson, G. Wilse" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/0R9G-EA66", "abstract": "The optical spectrum of samarium atoms trapped in matrices of argon and krypton at 4.2\u00b0K was examined. A simple basis for interpretation of the results is presented, in which the matrix perturbation is applied to the free atom in some quantum state of total angular momentum J.\r\n\r\nThe spectra can be correlated with the published data for SmI, but the complexity of the results, particularly in argon, make a detailed interpretation difficult. Some exceptionally sharp triplets with small splittings are considered to be derived from levels of the excited 4f^55d6s^2 configuration, none of which has previously been identified. Fluorescence was observed, corresponding to transitions from an excited state to the ^7F_1 and ^7F_2 levels of the ground state." }, { "name": "Rapaport, Seymour Alvin", "degree": "Masters", "year": "1962", "title": "I. Determination of the Quantum Yield of Thymidine Dinucleoside Irradiated by Ultra-Violet Light. II. Studies on the Inactivation by Ultra-Violet light of T\u2084D Bacteriophage Containing 5-Bromodesoxyuridine Substituted DNA", "advisor": "Delbruck, Max; Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05112010-154607309", "creators": [ { "name": { "family": "Rapaport", "given": "Seymour Alvin" }, "id": "Rapaport-Seymour-Alvin", "display_name": "Rapaport, Seymour Alvin" } ], "advisors": [ { "name": { "family": "Delbruck", "given": "Max" }, "id": "Delbr\u00fcck-M", "role": "advisor", "display_name": "Delbruck, Max" }, { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/V4NH-KB09", "abstract": "It has been found that when frozen thymine solutions are irradiated by ultra-violet light a photoreversible steady state is formed between thymine and a thymine diner. The suggestion has been made that such photoreversible chemical reactions might be involved in the photoreactivable mutations that occur upon irradiation of viruses with ultra-violet light. In order to give further credence to this thymine dinucleoside, TpT, was prepared and irradiated by ultra-violet light as described in Part I. A wavelength dependent photosteady state was found tobe established by this, and the quantum yield of the reaction of TpT to its photoproduct determined. The existence of this steady state and the magnitude of the quantum yield (0.002) support the supposition that similar reactions may cause the photoreversible mutations in viral DNA.\r\n\r\nPart II describes the determination of the action spectrum of in activation of plaque forming ability of T_4 bacteriophages grown in the presence of the thymidine analogue 5-bromodesoxyuridine (5-BD). Under these conditions 5-BD is substituted intothe DNA in place of thymidine. Such substituted DNA has been found to have increased sensitivity to UV light at 254 m\u03bc. The action spectrum was determined to more precisely define this increase in sensitivity and to obtain additional information regarding the UV inactivation of DNA. It was found that 5-BD substituted T_4 was uniformly more sensitive to UV than unsubstituted T_4; this effect was most striking in the 302 to 334 m\u03bc region where a factor of increased sensitivity up to 500 to 1000 times was noted. Furthermore, unlike unsubstituted T_4, killing of 5-BD substituted T_4 was found to follow \"one hit\" kinetics. The action spectrum indicated that 5-BD was directly involved in the initial steps of inactivation and was compatible with the possibility of transfer of absorbed light energy along the polynucleotide chain." }, { "name": "Takahashi, Masaaki", "degree": "Masters", "year": "1962", "title": "Nuclear Magnetic Resonance Studies of Some 1,1-Difluoro-3-Phenylcyclobutane Derivatives", "advisor": "Roberts, John D.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05062010-112117806", "creators": [ { "name": { "family": "Takahashi", "given": "Masaaki" }, "id": "Takahashi-Masaaki", "display_name": "Takahashi, Masaaki" } ], "advisors": [ { "name": { "family": "Roberts", "given": "John D." }, "id": "Roberts-J-D", "role": "advisor", "display_name": "Roberts, John D." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/481A-5Q94", "abstract": "1-Difluoro-2, 2-dichloro-3-methy1-3-phenylcyclobutane has been prepared by the cycloacidition of a-methylstyrene to 1,1-difluoro2, 2-dichloroethylene. A 2 cps long-range H-F spin-spin coupling has been observed over five consecutive saturated bonds in 1,1-difluoro2, 2-dichloro-3-methyl-3-phenylcyclobutane, involving one of the fluorines at the 1-position and the protons of the 3-methyl group. Analysis of the spectrum and that of the stereospecifically labeled 4-deutero derivatives suggest that the fluorine involved is the one cis to the methyl group.\r\n\r\nThe n. m. r. studies of 1,1-difluoro-3-bromo-3-phenylcyclobutane which was obtained by bromination of 1,1-difluoro-3-phenylcyclobutane with N-bromosuccinimide indicate that this molecule has on the average a more nearly planar cyclobutane ring than that of 1,1- difluoro-2, 2-dichloro-3-methyl-3-phenylcyclobutane. The four protons of the 2- Etna 4-positions are nearly magnetically equivalent, so that the spectrum of this compound is almost that of an ABX_4 system rather than an ABX_2Y_2 system. The theoretical calculations suggest that the chemical shift difference between X and Y is on the order of 1-2 cps. The chemical shift difference between the fluorines decreases in 1,1-difluoro-2, 2-dichloro-3-methy1-3-phenylcyclobutane and 1,1- difluoro-3-bromo-3-phenylcyclobutane with increasing temperature, suggesting that rapid ring-inversion is taking place. " }, { "name": "Laidlaw, William George", "degree": "Masters", "year": "1961", "title": "I. Linearization Methods for Systems not at Chemical Equilibrium. II. Equilibrium Pressures and Phase Compositions for Non-Ideal Mixtures", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:05072010-075038096", "creators": [ { "name": { "family": "Laidlaw", "given": "William George" }, "id": "Laidlaw-William-George", "display_name": "Laidlaw, William George" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/CF3P-3866", "abstract": "No abstract." }, { "name": "Tunder, Richard Steve", "degree": "Masters", "year": "1961", "title": "Development of a Competitive Technique for the Comparison of Strong Oxidation Inhibitors", "advisor": "Hammond, George Simms", "url": "https://resolver.caltech.edu/CaltechTHESIS:05062010-142421533", "creators": [ { "name": { "family": "Tunder", "given": "Richard Steve" }, "id": "Tunder-Richard-Steve", "display_name": "Tunder, Richard Steve" } ], "advisors": [ { "name": { "family": "Hammond", "given": "George Simms" }, "id": "Hammond-G-S", "role": "advisor", "display_name": "Hammond, George Simms" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/FZ6G-N196", "abstract": "The mechanism of the inhibited chain oxidation of \r\ncumene has been carefully investigated in previous studies.\r\nA competitive technique for determining relative efficiencies of strong inhibitors was to be tried in this study. Such a study might extend and verify work of a similar nature on weaker inhibitors. However the relative efficiencies determined were not constant. They varied because of possible side reactions of N,N'-dipheny1-p-phenylenediamine, the inhibitor chosen as a standard. For the same reason variation of the initial concentration of the standard inhibitor caused slight unexpected deviations in the results.\r\n\r\nHydroquinones were found to reduce N,N'-diphenyl-p-quinonimine, the oxidation product of the standard inhibitor, back to the inhibitor while stopping chains at the same time. As in previous studies, the strength of an inhibitor was found to increase with increasing ortho steric hindrance as well as with increasing electron density in the aromatic ring. Initiator concentration was found to be first order with respect to termination rate as would be expected in a chain reaction in which an inhibitor molecule stops two radical chains. The oxidation product formed from a phenolic inhibitor was found not to affect the standard inhibitor." }, { "name": "Wallace, Frederic Andrew", "degree": "Masters", "year": "1961", "title": "pH Titration Studies of the Acid Denaturation of Calf Thymus Deoxyribosenucleic Acid", "advisor": "Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04212010-142614826", "creators": [ { "name": { "family": "Wallace", "given": "Frederic Andrew" }, "id": "Wallace-Frederic-Andrew", "display_name": "Wallace, Frederic Andrew" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/MME6-8038", "abstract": "The acid denaturation of calf thymus deoxyribosenucleic acid (DNA) has been studied both by PH and \r\nspectrophotometric titration in the temperature range \r\n10 - 30\u00b0C and at ionic strengths 0.1 F and 0.5 F. The \r\nnumber of hydrogen ions bound by the DNA at any given \r\npH increased with increasing temperature and decreased \r\nwith increasing ionic strength. The number bound at \r\nany given pH was greater after denaturation. A model \r\nfor acid denaturation is proposed. The site of protonation of cytosine is discussed.\r\n" }, { "name": "Helman, William Phillip", "degree": "Masters", "year": "1960", "title": "Absorption and Dispersion of Sound in Reacting and Relaxing Fluids", "advisor": "Mazo, Robert M.; Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04222010-093442090", "creators": [ { "name": { "family": "Helman", "given": "William Phillip" }, "id": "Helman-William-Phillip", "display_name": "Helman, William Phillip" } ], "advisors": [ { "name": { "family": "Mazo", "given": "Robert M." }, "id": "Mazo-R-M", "role": "advisor", "display_name": "Mazo, Robert M." }, { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/DW69-PB79", "abstract": "The hydrodynamic equations for a chemically reacting and internally relaxing fluid are obtained in a suitable form, and, are then used to find the dispertion and absorption of plane infinitesimal sound waves, Only the case of no viscosity, heat conduction, and diffusion is considered. It is shown that the interference effects between relaxation processes are not, in general, negligible compared to the relaxation effects themselves. A specific example, that of oxygen gas at 2500\u00b0 K is considered giving an idea of the relative magnitudes of the several effects which are involved.\r\n" }, { "name": "Porterfield, William Wendell", "degree": "Masters", "year": "1960", "title": "Some Electron Paramagnetic Resonance Studies of Bis-Cyclopentadienyl Vanadium", "advisor": "McConnell, Harden M.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04232010-114434337", "creators": [ { "name": { "family": "Porterfield", "given": "William Wendell" }, "id": "Porterfield-William-Wendell", "display_name": "Porterfield, William Wendell" } ], "advisors": [ { "name": { "family": "McConnell", "given": "Harden M." }, "id": "McConnell-H-M", "role": "advisor", "display_name": "McConnell, Harden M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/7D95-T093", "abstract": "Section I: \r\nBis-cyclopentadienyl vanadium was examined by electron paramagnetic resonance (EPR) in dilute benzene solution (1). Vanadium nuclear hyperfine splittings equal to 77 Mc centered at g=2.00 were found, providing experimental evidence that the unpaired electrons occupy orbitals with a very small amount of s character. The orbital ground state is shown to be a singlet. It follows that one of the three unpaired electrons must occupy an orbital of a_(1g) symmetry, the other two orbitals of e_g symmetry, and that the g factor is nearly isotropic.\r\nEPR spectra taken of an oxidized solution show hyperfine structure 210 Mc wide at g=1.99, indicating the possible presence of bis-cyclopentadienyl vanadyl, V0(C_5H_5)_2.\r\nSection II: \r\nEPR spectra were taken of a dilute single crystal of bis-cyclopentadienyl vanadium in ferrocene and the angular dependence of the spectra studied. The spectral lines changed from g^e\u22432 at a position with H_0 approximately parallel to the molecular symmetry axis to g^e=3.77 with\r\nH_0 perpendicular to this axis, where h\u03bd=g^e\u03b2H. This angular dependence indicates a zero-field energy level splitting of 47.0 kMc or 1.57 cm^(-1). The bis-cyclopentadienyl vanadium was synthesized by a process originated by Wilkinson (2) but some minor changes were found desirable in product recovery.\r\n" }, { "name": "Bromberg, J. Philip", "degree": "Masters", "year": "1959", "title": "Experiments in Nuclear Magnetic Resonance", "advisor": "McConnell, Harden M.", "url": "https://resolver.caltech.edu/CaltechTHESIS:11242009-075328528", "creators": [ { "name": { "family": "Bromberg", "given": "J. Philip" }, "id": "Bromberg-J-Philip", "display_name": "Bromberg, J. Philip" } ], "advisors": [ { "name": { "family": "McConnell", "given": "Harden M." }, "id": "McConnell-H-M", "role": "advisor", "display_name": "McConnell, Harden M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/F20V-N746", "abstract": "I. Proton and cobalt resonances were observed in single crystals of Co(NH_2CH_2CH_2NH_2)_3Cl_3 ^3H_2_O. The cobalt spectrum consists of a maximum of seven lines whose separation follows a (3cos^2\u03b8 \u2013 1) dependence quite closely where \u03b8 is the angle between the c-axis of the crystal and H_o. The spectrum is fully explained on the basis of quadrupole interaction. Two sets of doublets were found for the proton resonances; an inner, very narrow set following a dependence similar to the cobalt resonance, and a pair of outer broad peaks which overlap the sharp peaks. The narrowness of the central peaks is attributed to internal rotation of one of the proton bearing groups.\r\n\r\nII. A summary is given of various high resolution spectra of compounds related to phosphine.\r\n" }, { "name": "McGriff, Richard Bernard", "degree": "Masters", "year": "1959", "title": "The Synthesis of 1-Keto-3-Carbomethoxy-1,2,3,4-Tetrahydroisequinoline", "advisor": "Niemann, Carl G.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05102010-153156629", "creators": [ { "name": { "family": "McGriff", "given": "Richard Bernard" }, "id": "McGriff-Richard-Bernard", "display_name": "McGriff, Richard Bernard" } ], "advisors": [ { "name": { "family": "Niemann", "given": "Carl G." }, "id": "Niemann-C-G", "role": "advisor", "display_name": "Niemann, Carl G." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/B06Z-W247", "abstract": "The preparation of 1-keto-3-carbomethoxy-1,2,3,4-tetrahydroisequinoline byt wo routes is described. The first involves hydrolysis of the adduct of a-bromo-o-tolunitrile and acetamidomalinicester to 1-keto-3-carboxy-1,2,3,4-tetrahydroisequinoline. Esterification of this acid yields the desired ester. The second route involves the condensation of phenylalanine with formaldehyde to form 3-carboxy-1,2,3,4-tetrahydroisequinoline. The benzoyle derivative of this compounds is smoothly oxidized by cold permanganate to N-benzoyl (o-carboxyphenyl) alanine, wich is convert by acid hydrolysis to 1-keto-3-carboxy-1,2,3,4-tetrahydroisequinoline and benzoic acid. Preliminary experiments show that 1-keto-3-carboxy-1,2,3,4-tetrahydroisequinoline is hydrolyzed by a-chymotrypsin, and indicate that both forms are hydrolyzed,albeit at differing rates." }, { "name": "Kraus, Bernhard August", "degree": "Masters", "year": "1958", "title": "The Photoisomerization of Azobenzene at 77\u00b0K in a Rigid Solvent and at Room Temperature", "advisor": "Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05032010-130844301", "creators": [ { "name": { "family": "Kraus", "given": "Bernhard August" }, "id": "Kraus-Bernhard-August", "display_name": "Kraus, Bernhard August" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/RDAG-4773", "abstract": "The photoisomerization of azobenzene has been studied at room temperature in ethanol and P. Me.H., and at 77\u00b0K in a P.Me.H. rigid solvent. At room temperature, the photostationary state composition is 74% trans (and 26 % cis) in ethanol and 77 % trans in P.Me.H.; it is 98 % trans in P.Me.H. at 77\u00b0K. It has been shown that both the trans to cis and the cis to trans photoisomerizations occur in the rigid solvent at liquid nitrogen temperature.\r\n\r\nThe spectra and molar extinction coefficients have been determined at room temperature for trans azobenzene in ethanol and P.Me.H. Other spectra were taken of azobenzene: at the photostationary state, at room temperature in ethanol and P.Me.H., and at 77\u00b0K in P.Me.H.; at 77\u00b0K of 100 % and 77 % trans in P.Me.H.\r\n\r\nIt has been shown that the photoisomerization occurs more readily by irradiation in the visible, than in the ultraviolet region. A new low temperature cell has been designed and used.\r\n" }, { "name": "Brady, William Thomas", "degree": "Masters", "year": "1957", "title": "The Synthesis of O-Methyl-N-Acetyl-L-Tyrosine", "advisor": "Niemann, Carl G.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04292010-095951946", "creators": [ { "name": { "family": "Brady", "given": "William Thomas" }, "id": "Brady-William-Thomas", "display_name": "Brady, William Thomas" } ], "advisors": [ { "name": { "family": "Niemann", "given": "Carl G." }, "id": "Niemann-C-G", "role": "advisor", "display_name": "Niemann, Carl G." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/2XEN-8E12", "abstract": "An efficient method of preparing N-acetyl-L-tyrosine methyl ester is described. This compound has been converted to the optically pure O-methyl derivative by reaction with diazomethane. The saponification of N-acetyl-L-tyrosine methyl ester is a more convenient rout to N-acetyl-L-tyrosine than the direct acetylation of L-tyrosine. N-acetyl-L-tyrosine can be converted to optically pure O-methylN-acetyl-L-tyrosine via the Williamson synthesis. The preparation of several other derivatives of L- tyrosine is also described.\r\n" }, { "name": "Hutchinson, William Day", "degree": "Masters", "year": "1957", "title": "An Ultracentrifugal Study of the Dissociation of Human Carboxyhemoglobin", "advisor": "Vinograd, Jerome Rubin", "url": "https://resolver.caltech.edu/CaltechTHESIS:04262010-094002832", "creators": [ { "name": { "family": "Hutchinson", "given": "William Day" }, "id": "Hutchinson-William-Day", "display_name": "Hutchinson, William Day" } ], "advisors": [ { "name": { "family": "Vinograd", "given": "Jerome Rubin" }, "id": "Vinograd-J-R", "role": "advisor", "display_name": "Vinograd, Jerome Rubin" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/W8JC-7T49", "abstract": "The dissociation of human carboxyhemoglobin has been investigated by means of sedimentation velocity measurements. Sedimentation studies on this protein have been extended to concentrations as low as 0.002% by the use of absorption optics. Hemoglobin was observed to dissociate increasingly as the pH was changed from 7 to 5. Apparent dissociation constants at each pH have been calculated. Values of the apparent specific volume of human carboxyhemoglobin have been found." }, { "name": "Bradbury, James Thomas", "degree": "Masters", "year": "1956", "title": "I. Development of Paper Electrophoresis Technique for Observation of Microgram Quantities of Protein. II. Electrophoretic and Ultra-Centrifugal Studies of Soluble Antigen-Antibody Complexes as a Method of Determining Antibody and Antigen Valences", "advisor": "Campbell, Dan Hampton; Vinograd, Jerome Rubin", "url": "https://resolver.caltech.edu/CaltechETD:etd-03182004-155047", "creators": [ { "name": { "family": "Bradbury", "given": "James Thomas" }, "id": "Bradbury-James-Thomas", "display_name": "Bradbury, James Thomas" } ], "advisors": [ { "name": { "family": "Campbell", "given": "Dan Hampton" }, "id": "Campbell-D-H", "role": "advisor", "display_name": "Campbell, Dan Hampton" }, { "name": { "family": "Vinograd", "given": "Jerome Rubin" }, "id": "Vinograd-J-R", "role": "advisor", "display_name": "Vinograd, Jerome Rubin" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/9CZJ-ZS08", "abstract": "Quantities of protein as small as five micrograms can be positively detected after electrophoresis on paper if strong adsorption to the paper, known as tailing, is prevented. Adding 0.1% gelatin to the buffer solution used to soak the paper is the simplest way to reduce tailing, and allows the conventional bromphenol blue stain to be used to locate the protein. A protein as nearly identical to the sample as possible eliminates tailing more completely than gelatin, and can be used if the sample can be located in a background of the other protein. Making the sample fluorescent under ultraviolet light by coupling 1-dimethylaminonaphthlalene-5-sulfonyl chloride to it before electrophoresis is an effective way to locate the sample in the presence of otherwise identical proteins. Oxidation of the paper with nitrogen dioxide to reduce tailing has been attempted, but the method has not been refined to a practical degree of effectiveness.\r\n\r\nPaper electrophoresis of BSA-rabbit anti-BSA complexes shows two zones attributed to the Ag2Ab and Ag3Ab2 complexes, in qualitative agreement with moving boundary electrophoresis and ultracentrifugation by Singer and Campbell. As a supplementary argument as to the identity of the complexes, a simple statistical theory is developed to show the relative proportions of different complexes to be expected from antigens and antibodies of given valences, or to show the valences of antigens and antibodies from the quantities of the different complexes formed. Using the ultracentrifugal data of Singer and Campbell in the theoretical equations limits the valence of the antibodies to a value close to two, and the valence of the BSA antigen to a value around five." }, { "name": "King, James", "degree": "Masters", "year": "1955", "title": "The Kinetics of the Oxygenation of Ferrous Ion in Phosphoric Acid Containing Pyrophosphate", "advisor": "Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechETD:etd-01072004-101648", "creators": [ { "name": { "family": "King", "given": "James" }, "id": "King-James", "display_name": "King, James" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/9W2D-4P13", "abstract": "NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document.\r\n\t\r\nThe kinetics of the ferrous-oxygen reaction in an acid solution containing phosphate and pyrophosphate has been investigated. The rate law at [...] is [...]. Sodium perchlorate is used to maintain the ionic strength at 1.0-l.1M. There is inhibition due to ferric ion. This phase of the reaction has not been investigated. It is believed that the inhibition is due to the insolubility of ferric pyrophosphate at high concentrations and to the formation of complexes at low concentrations. The following mechanism, suggested by Weiss, is consistent with the experimental results. [...]. The rate of the reaction is given by [...]. The phosphate and pyrophosphate species catalyse the reaction through complex ion formation." }, { "name": "Hershman, Jerome Marshall", "degree": "Masters", "year": "1954", "title": "Preparation and Characterization by Streaming Birefringence of Sodium Desoxyribonucleate", "advisor": "Rich, Alexander", "url": "https://resolver.caltech.edu/CaltechETD:etd-05062003-095853", "creators": [ { "name": { "family": "Hershman", "given": "Jerome Marshall" }, "id": "Hershman-Jerome-Marshall", "display_name": "Hershman, Jerome Marshall" } ], "advisors": [ { "name": { "family": "Rich", "given": "Alexander" }, "id": "Rich-Alexander", "role": "advisor", "display_name": "Rich, Alexander" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/8XHJ-5E14", "abstract": "NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document.\r\n\r\nThree preparations of the sodium salt of desoxyribonucleic acid were isolated from calf thymus by a method expected to give minimal or no depolymerization. In addition, preparations were made from calf spleen and bull testis tissues.\r\n\r\nStreaming birefringence measurements indicate that the distributions of molecular length are identical in the calf thymus preparations. The apparent molecular lengths range from 7,500 to 11,500[...]. The sodium desoxyribonucleate from testis appeared to be significantly shorter; that from spleen was intermediate between thymus and testis. The distributions of molecular length of two calf thymus preparations isolated by N. Simmons were compared with those prepared here.\r\n\r\nSeveral explanations are put forth to explain the polydispersity and discrepancies between preparations." }, { "name": "Stottlemyer, Quayton Ray", "degree": "Masters", "year": "1954", "title": "Investigation of the Behavior of the Aqueous I\u2083\u207b-I\u2082-I\u207b System Following Intense Irradiation", "advisor": "Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechETD:etd-01272004-154020", "creators": [ { "name": { "family": "Stottlemyer", "given": "Quayton Ray" }, "id": "Stottlemyer-Quayton-Ray", "display_name": "Stottlemyer, Quayton Ray" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/CSV2-DQ22", "abstract": "NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document.\r\n \r\nAcidified aqueous solutions containing [...], [...], and [...] have been irradiated by a high intensity flash lamp and the resulting change in the optical density of the solution has been observed spectrophotometrically as a function of time after the flash.\r\n\r\nImmediately following the flash, there is an increase in the optical density of the solution. This is attributed to the photochemical production of the diiodide ion, [...], by reaction (1) and/or reaction (2) and (3). [...] [...] [...].\r\n\r\nThe disappearance of the colored species, in about 1.5--8 milliseconds after the flash, has been found to be kinetically of the second order with respect to that species and has been explained in terms of the recombination of [...], principally by equation (4). [...] [...] [...].\r\n\r\nOn the basis of these assumptions, the value of [...] has been determined at wave lengths 365 mmu. and 435 mmu. for [...] ranging from [...] to [...] M. The experimental dependence of the rate of disappearance of [...] on [...] has been found to agree qualitatively with the theoretical equation: [...].\r\n\r\nThe calculated value of [...] has been found to vary with the wave length of the light used to observe the reaction as predicted by the equation: [...].\r\n\r\nThe presence of [...] in concentrations about [...] caused a slight increase in the value of [...], which was attributed to one or both of the reactions: [...] [...]. [...] in concentrations less than [...] appeared to decrease the rate of disappearance of [...]; for this anomalous effect no explanation is given.\r\n\r\nExperiments performed in which a large percentage of the light absorbed by [...] was cut off by filters produced correspondingly smaller phenomena but gave no conclusive evidence as to the relative proportion of [...] and [...] dissociated by the irradiation.\r\n\r\nAn extensive summary of data is presented." }, { "name": "Ferington, Thomas Edwin", "degree": "Masters", "year": "1952", "title": "Observations on the Interaction of Ion Exchange Resins with Some Cupric Compounds", "advisor": "Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10162017-102130831", "creators": [ { "name": { "family": "Ferington", "given": "Thomas Edwin" }, "id": "Ferington-Thomas-Edwin", "display_name": "Ferington, Thomas Edwin" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/CMRX-8587", "abstract": "The interaction of the Sulfonic Acid Resin,\r\nNalcite HCR, with CuII halide solutions was studied\r\nin hope of obtaining dissociation constants for the complex \r\nions CuX+. The fact that CuX+ is absorbed by\r\nthe resin to an appreciable extent prevented the\r\nattainmnet of this goal. It was found in the case of\r\nCuF+ that the complex ion is absorbed even more strongly\r\nthan Cu++. The presence of a Cu++-F- complex\r\nwas indicated by spectrophotometric observations.
\r\n\r\nThe action of the carboxylic acid resin, IRC - 50\r\nwas studied in a column. It was found that the \r\nvolume of the resin in the Cu++ salt form depended\r\non the salt with which the resin was treated. In the\r\ncase of solutions of Cu(OAc)2 it was found that Cu(OAc)+\r\nwas taken into the resin as well as Cu++.
\r\n\r\nA titration curve for IRC - 50 with NaOH in\r\nsolutions of ionic strength one is given.
" }, { "name": "Rosser, Willis Andrew, Jr.", "degree": "Masters", "year": "1952", "title": "Hydrogen Bonding in Alcohols", "advisor": "Badger, Richard McLean", "url": "https://resolver.caltech.edu/CaltechTHESIS:10182017-132702543", "creators": [ { "name": { "family": "Rosser", "given": "Willis Andrew, Jr." }, "id": "Rosser-Willis-Andrew", "display_name": "Rosser, Willis Andrew, Jr." } ], "advisors": [ { "name": { "family": "Badger", "given": "Richard McLean" }, "id": "Badger-R-M", "role": "advisor", "display_name": "Badger, Richard McLean" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/2S8Z-D418", "abstract": "It is usually assumed in optical absorption work \r\nthat the natural stretching frequency of the hydroxyl\r\ngroup in an alcohol is appreciably changed by hydrogen\r\nbonding. A survey of work relating to hydrogen bonding\r\nin alcohols favors this assumption. Moreover, it appears\r\nthat the deviation of alcohols in solvents such as carbon\r\ntetrachloride from Henry's law is primarily due to\r\nhydrogen bonding polymerization, the extent of such \r\ndeviation being the same for the lower aliphatic alcohols\r\nand phenol.
\r\n\r\nOptical transmission measurements on dilute solutions\r\nof methyl alcohol and of ethyl alcohol in carbon\r\ntetrachloride were used to determine for these alcohols the\r\ndimerization constants associated with the reaction.
\r\n\r\n\r\n2 ROH \u2192 (ROH)2
\r\n\r\n\r\nThese constants in turn were used in support of the \r\ncontention that the polymerization constants associated with\r\nthe reactions
\r\n\r\n(ROH)g-1 + ROH \u2192 (ROH)g
\r\n\r\nare not independent of g as has been assumed on occasion.
\r\n\r\nThe viscosity of solutions of alcohols in carbon\r\ntetrachloride is briefly discussed in a semi-quantitative\r\nmanner.
" }, { "name": "Buck, Richard Pierson", "degree": "Masters", "year": "1951", "title": "Studies on the Use of Coulometric and Amperometric Analysis", "advisor": "Swift, Ernest H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:08092017-100407498", "creators": [ { "name": { "family": "Buck", "given": "Richard Pierson" }, "id": "Buck-Richard-Pierson", "display_name": "Buck, Richard Pierson" } ], "advisors": [ { "name": { "family": "Swift", "given": "Ernest H." }, "id": "Swift-E-H", "role": "advisor", "display_name": "Swift, Ernest H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/QJZB-MY25", "abstract": "A coulometric titration is described in which unipositive\r\nthallium is oxidized to the tripositive state by electrolytically\r\ngenerated bromine or chlorine. The end-point is determined \r\namperometrically by measuring the current between\r\ntwo platinum electrodes with an impressed potential difference\r\nof 200 millivolts. Confirmatory analyses have shown an accuracy of 0.2% for 93\r\nto 200 microgram samples, and of 0.1%\r\nfor samples of from 200 to 1900 micrograms.
\r\n\r\nThe application of dual intermediates to secondary coulometric titrations\r\nwith an amperometric end point has been studied.\r\nCupric copper and bromide have been used for the alternate electrolytic \r\ngeneration of bromine and cuprous copper for the purpose of titrating\r\na substance exhibiting a slow rate of reaction with bromine.\r\nA procedure is described by which aniline has been titrated in\r\nquantities of from 13 to 280 micrograms with an average error without regard \r\nto sign of less than 0.4 micrograms.
\r\n\r\nA study has been made of the bromine-bromide diffusion current,\r\nthe effects of the concentrations of bromine, bromide\r\nand hydrogen ion; the minimum bromide ion concentration necessary\r\nto maintain generation of bromine with 100% current efficiency was determined.
\r\n\r\nStudies have been made of the diffusion-controlled currents observed when potential\r\ndifferences, less than the decomposition potential, are impressed upon two\r\nplatinized-platinum electrodes in solutions of hydrochloric acid which are 0.1 VF\r\nin potassium chloride and saturated with hydrogen gas. The effects of the \r\nelectrode size and material, the applied potential, and the presence of \r\noxygen and nitrogen gas are described.
" }, { "name": "Goeddel, Walter Van Norman", "degree": "Masters", "year": "1951", "title": "An Investigation of the Manganese Indium System", "advisor": "Yost, Don M.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10162017-141948279", "creators": [ { "name": { "family": "Goeddel", "given": "Walter Van Norman" }, "id": "Goeddel-Walter-Van-Norman", "display_name": "Goeddel, Walter Van Norman" } ], "advisors": [ { "name": { "family": "Yost", "given": "Don M." }, "id": "Yost-D-M", "role": "advisor", "display_name": "Yost, Don M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/CBKV-KJ81", "abstract": "A preliminary phase-equilibria study has been made of the\r\nmanganese-indium alloy system by means of thermal analysis\r\n(cooling curves) and metallographic studies (photomicrographs).\r\nFerromagnetism has been found to exist in alloys containing up\r\nto 70 atom percent manganese and has tentatively been attributed\r\nto the compound Mn2In. A phase diagram has been proposed, on\r\nthe basis of the data obtained, in which the indium rich portion\r\nof the system consists of indium plus Mn2In, while the manganese\r\nrich portion is made up of a manganese solid solution.\r\nAdditional experiments have been outlined to further identify\r\nthe nature and extent of the phases present. A new scheme of\r\nchemical analysis has been applied to the alloys with good success." }, { "name": "Petracek, Francis James", "degree": "Masters", "year": "1951", "title": "A Study of Some Plant Carotenoids and of Certain Colorless Fluorescing Compounds of Marine Origin", "advisor": "Zechmeister, Laszlo", "url": "https://resolver.caltech.edu/CaltechTHESIS:07282025-183252396", "creators": [ { "name": { "family": "Petracek", "given": "Francis James" }, "id": "Petracek-Francis-James", "display_name": "Petracek, Francis James" } ], "advisors": [ { "name": { "family": "Zechmeister", "given": "Laszlo" }, "id": "Zechmeister-L", "role": "advisor", "display_name": "Zechmeister, Laszlo" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/2ge3-te76", "abstract": "The sudden color change observed during the ripening\r\nof the Pyracantha gibbsi ynnanensis berries was investigated.\r\nIt was caused by the rapid formation of an anthocyanin, \r\nnot by the cis\u2192trans isomerization of a polycis\r\ncarotenoid.
\r\n\r\n30 gm. of all-trans lycopene were stereoisomerized by\r\nrefluxing in benzene, and the solutions were chromatographed\r\nto separate the very small amounts of polycis lycopenes that\r\nshould be present according to theoretical considerations.\r\nFour chromatographically separable pigments were isolated\r\nfrom the filtrate which would have contained any polycis\r\nlycopenes, but none of the four pigments belonged to the\r\nstereoisomerica lycopene sot.
\r\n\r\nThe carotenoid pigments and fluorescing substances\r\nextracted from several marine sources were isolated and\r\ninvestigated by chromatographic and spectroscopic methods.\r\nA provitamin D sterol was identified and isolated in an\r\nimpure form from one of these marine sources, the Thoracophelia \r\nmucronata.
" }, { "name": "Craig, Roy Phillip", "degree": "Masters", "year": "1950", "title": "Radiochemical Investigation of the Kinetics of the Electron Exchange Between the Oxidation States of Tin", "advisor": "Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechTHESIS:06162025-180659877", "creators": [ { "name": { "family": "Craig", "given": "Roy Phillip" }, "id": "Craig-Roy-Phillip", "display_name": "Craig, Roy Phillip" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/4e56-hq86", "abstract": "The kinetics of the electron exchange between SnII and SnIV\r\nin 10.0 f HCl have been investigated by the use of a \r\nradio-active tracer. It is found that the rate of exchange\r\nis proportional to the product of the SnII and SnIV concentrations.\r\nIn the HCl concentration range between 9.0 f and 11.0 f,\r\nthe exchange rate is found to be proportional to the 0.3 power of the HCl activity,\r\ngiving the empirical rate equation R = k [SnII] [SnIV] (HCl)0.3
\r\n\r\nRadio-active exchange experiments carried out at 0\u00b0 C.\r\nand at 25.2\u00b0C. show this exchange to have an activation\r\nenergy of 10.7 Kcal. per mole. The exchange is found to be\r\nhomogeneous.
\r\n\r\nIt is found that exposure of the SnII-SnIV solutions\r\nto illumination from a capillary Hg arc gives a marked photochemical\r\nincrease in the rate of electron exchange between\r\nthe two valence states.
\r\n\r\nPreliminary spectrophotometric investigations of cobalt-glycine\r\nsystems also have been made.
" }, { "name": "Leroux, Pierre Jean", "degree": "Masters", "year": "1949", "title": "Studies on the Rate of Hydrolysis of Sec-Butyl P-Toluenesulfonate", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:09092025-003348891", "creators": [ { "name": { "family": "Leroux", "given": "Pierre Jean" }, "id": "Leroux-Pierre-Jean", "display_name": "Leroux, Pierre Jean" } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/7j05-b860", "abstract": "The rate of hydrolysis of sec-butyl p-toluenesulfonate has been investigated in different solvent mixtures of acetone and water and dioxane and water.
\r\nThe mechanism of the hydrolysis of this ester, which is similar to the secondary alkyl halides, is situated on the border line between the unimolecular dissociation and the bimolecular displacement.
\r\nIt has been found that the rate is proportional to a certain function of the dielectric strength of the solvent but that the proportionality factor is much larger when the solvating power of the medium is high.
\r\nBy studying the ionic strength effect, the so called \"mass law effect\", and the hydroxyl ion influence on the rate, one has come to the conclusion that both un1molecular and bimolecular mechanisms are involved in this hydrolysis.
\r\nFor low values of the dielectric constant of the medium, the bimolecular mechanism seems to be present to the larger extent while for high values of this function the unimolecular dissociation is predominant.
" }, { "name": "Mirza, Rafat", "degree": "Masters", "year": "1949", "title": "Some Synthetical Experiments with 4-Quinazolone", "advisor": "Koepfli, Joseph Blake", "url": "https://resolver.caltech.edu/CaltechTHESIS:06172025-224633884", "creators": [ { "name": { "family": "Mirza", "given": "Rafat" }, "id": "Mirza-Rafat", "display_name": "Mirza, Rafat" } ], "advisors": [ { "name": { "family": "Koepfli", "given": "Joseph Blake" }, "id": "Koepfli-J-B", "role": "advisor", "display_name": "Koepfli, Joseph Blake" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/1kmx-c424", "abstract": "An exceedingly labile compound has been isolated by the\r\ndirect acetylation of 4-quinazolone. The same compound was obtained by reacting silver acetate and 4-chlorquinazoline. Attempts to prepare 3-acetyl-4-quinaazolone by the oxidation of 3-acetyl-3, 4-dihydroquinazoline were not successful, and only 4-quinazolone was isolated as the oxidation product.
\r\nAttempts to attach the alkylaminoalkyl side chains to 4-quinazolone showed that such secondary amines undergo self condensation rather than react with 4-quinazolone. However, it was possible to introduce a dialkylaminoalkyl side chain, and 3-(diethylaminoethyl)-4-quinazolone has been synthesized and is being tested for possible antimalarial activity.
\r\n3-Acetonyl-4-quinazolone gave a well defined crystalline\r\nsolid with diethylamine under the conditions of the Mannich reaction. The analysis of this compound did not agree with the values for the expected compound, and the structure has not been elucidated.
" }, { "name": "Monroe, Emmett Paul", "degree": "Masters", "year": "1949", "title": "I. Derivatives of Spiro (3,3) Heptanetetra Carboxylic Acid. II. Attempted New Synthesis of Cis-2 Butene-1, 4-Diol", "advisor": "Buchman, Edwin Raphael", "url": "https://resolver.caltech.edu/CaltechETD:etd-02122009-093328", "creators": [ { "name": { "family": "Monroe", "given": "Emmett Paul" }, "id": "Monroe-Emmett-Paul", "display_name": "Monroe, Emmett Paul" } ], "advisors": [ { "name": { "family": "Buchman", "given": "Edwin Raphael" }, "id": "Buchman-E-R", "role": "advisor", "display_name": "Buchman, Edwin Raphael" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/VB67-1R54", "abstract": "I. DERIVATIVES OF SPIRO(3,3) HEPTANETETRACARBOXYLIC ACID:\r\n\r\nThe isolation of the isoamyl ester of spiroheptanetetra-carboxylic acid, prepared by the condensation of sodiomalonic ester with pentaerythrityl tetrabromide in isoamyl alcohol is reported. The synthetic method is that of Fecht as modified by Backer and Schurink. Pentaerythrityl benzenesulfonate is substituted for the bromide in the reaction with the malonic ester, but the yield is found to be much poorer. Attempts to prepare the ethyl ester of spiroheptanetetracarboxylic acid by using pentaerythrityl benzenesulfonate in ethyl alcohol solvent, and pentaerythrityl bromide in excess malonate and xylene solvents are described. These experiments did not produce a practical synthesis of the ethyl ester.\r\n\r\nThe unsuccessful attempt to reduce the isoamyl ester of spiroheptanetetracarboxylic acid with lithium aluminum hydride is described.\r\n\r\nII. ATTEMPTED NEW SYNTHESIS OF CIS-2-BUTENE-,4-DIOL:\r\n\r\nA synthesis of cis-2-butene-1,4-diol by the reduction of maleic anhydride with lithium aluminum hydride is attempted. Two experiments are described, one of which employs an aqueous system in the isolation of the product, the other a non-aqueous system. No amount of any consequence of the diol was obtained. A discussion of lithium aluminum hydride as a reducing agent is included.\r\n" }, { "name": "Rosicky, Fred George", "degree": "Masters", "year": "1949", "title": "An Improved Synthesis of 2-Nitro-6-Aminotoluene", "advisor": "Niemann, Carl G.", "url": "https://resolver.caltech.edu/CaltechTHESIS:09242025-191121445", "creators": [ { "name": { "family": "Rosicky", "given": "Fred George" }, "id": "Rosicky-Fred-George", "display_name": "Rosicky, Fred George" } ], "advisors": [ { "name": { "family": "Niemann", "given": "Carl G." }, "id": "Niemann-C-G", "role": "advisor", "display_name": "Niemann, Carl G." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/8nyx-ge59", "abstract": "Aromatic fluorides have been prepared and known for a long time (1), but not much work has been done with them until comparatively recently when they have assumed considerable importance as starting materials for the preparation of fluorinated \u221d-amino acids. A considerable number of fluorinated \u221d-amino acids have been prepared. during the past fifteen years, chiefly fluorine derivatives of phenylalanine (2), tyrosine (3,4,5,6,7), and thyronine (5,8).
\r\n\r\nFluorine derivatives of tryptophane have to date not been described in the literature. The compound 2-nitro-6-fluorotoluene was desired as a starting material later to be used in an attempt to synthesize a r1uorine derivative of tryptophane; hence this work was undertaken in an effort to achieve an improved synthesis of the nitrofluorotoluene.
" }, { "name": "Showell, John Sheldon", "degree": "Masters", "year": "1949", "title": "Studies on the Kinetics of the Addition of Acetic Acid to Isobutene", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:09172025-021803490", "creators": [ { "name": { "family": "Showell", "given": "John Sheldon" }, "id": "Showell-John-Sheldon", "display_name": "Showell, John Sheldon" } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/5kmx-0d09", "abstract": "The kinetics of the addition of acetic acid to isobutene with anhydrous and water-containing acetic acid as the\r\nsolvent were studied. The rate was determined by following the changing unsaturation with bromine. The reaction was found to be sensitive to the presence of water, tertiary butyl alcohol being the principal product, when water was present and no polymerization was observed. Under anhydrous conditions the tertiary butyl acetate was formed and the isobutene was observed to polymerize. The kinetics of the anhydrous reaction were theoretically treated quantitatively and the rate step was shown to be the addition of the proton to the isobutene. The water containing conditions were studied, but could not be quantitatively interpreted due to the complex equilibrium system set up, the results were however interpreted qualitatively. The concept of the carbonium ion intermediate of Whitmore was shown to be consistent with the esterification and t he polymerization reaction." }, { "name": "Browne, Charles Idol", "degree": "Masters", "year": "1948", "title": "Spectrophotometric and Radiochemical Investigation of the Interaction Between the Oxidation States of Tin in Aqueous Solution", "advisor": "Davidson, Norman R.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05162025-181639771", "creators": [ { "name": { "family": "Browne", "given": "Charles Idol" }, "id": "Browne-Charles-Idol", "display_name": "Browne, Charles Idol" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/rn6j-5f45", "abstract": "The spectrophotometry and radioactive exchange of\r\nSnII and SnIV in hydrochloric acid have been investigated.\r\nIt is found that mixtures of SnII and SnIV in hydrochloric\r\nacid exhibit anomalous absorption of ultra-violet light\r\nand that with the extent of this anomalous absorption is\r\nproportional to the product of the SnII and SnIV concentrations,\r\nimplying absorption by a dimeric complex of\r\nSnII and SnIV.
\r\n\r\nIt is found that SnII and SnIV exchange radioactivity\r\nmoderately slowly (half-exchange time about 7 min.) in 9N\r\nhydrochloric acid. The extent of exchange upon immediate\r\nseparation after mixing is about 17%, which is\r\neither a function of the separation method or an indication\r\nthat only certain chloride complexes of tin exchange.
\r\n\r\nIt is found that CuI and CuII exhibit interaction\r\nabsorption in 6N HCl
" }, { "name": "George, Joseph Doyle", "degree": "Masters", "year": "1948", "title": "Kinetics of the Acid-Catalyzed Hydrolysis of Amine Disulfonate Ion. The Third Ionization Constant of Amine Disulfonic Acid", "advisor": "Davidson, Norman R.; Yost, Don M.", "url": "https://resolver.caltech.edu/CaltechTHESIS:06042025-200212097", "creators": [ { "name": { "family": "George", "given": "Joseph Doyle" }, "id": "George-Joseph-Doyle", "display_name": "George, Joseph Doyle" } ], "advisors": [ { "name": { "family": "Davidson", "given": "Norman R." }, "id": "Davidson-N-R", "role": "advisor", "display_name": "Davidson, Norman R." }, { "name": { "family": "Yost", "given": "Don M." }, "id": "Yost-D-M", "role": "advisor", "display_name": "Yost, Don M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/bdxy-bd03", "abstract": "The rate of the acid-catalyzed hydrolysis of amine\r\ndisulfonate ion, HN(SO3)=2, in water solution has been\r\nthoroughly studied over the temperature range 25-45\u00b0 C.\r\nThe effect of varying the concentration of reactants, the\r\neffect of ionic strength (neutral salt effect), and the\r\neffect of temperature have been studied. All results at\r\nconstant ionic strength confirm the rate equation
\r\n\r\n- d(HN(SO3)=2)/dt = k(H+)(SO3)=2)
\r\n\r\nif the equilibrium between sulfate ion and hydrogen ion is\r\ntaken into account. The uncatalyzed hydrolysis was found\r\nto have an undetectable rate compared to the rate of the\r\ncatalyzed reaction.
\r\n\r\nThe variation of the rate constant with ionic strength\r\nimplies that the charge product of the ions involved in the\r\nrate determining reaction is -2.
\r\n\r\nThe internal energy of activation, \u0394E\u2260, was found to\r\nbe 23.5 \u00b1 1 Kcal., and the entropy of activation, \u0394S\u2260, was\r\nfound to be +7.2 \u00b1 1.5 e.u. for the reaction at zero\r\nionic strength.
\r\n\r\nA mechanism involving an activated complex of amine\r\ndisulfonate ion and hydronium ion may be invoked to explain\r\nthese results.
\r\n\r\nIn addition, the ionization function (classical ionization\r\nconstant) for the equilibrium
\r\n\r\nHN(SO3)=2) = H+ + N(SO3)=2)
\r\n\r\nwas measured in a sodium chloride solution at an ionic\r\nstrength of 1.00 at 25\u00b0 C. It was found that
\r\n\r\n(H+)N(SO3)=2)/HN(SO3)=2) = 3.2 x 10-9.
" }, { "name": "Hoyer, Horst Walter", "degree": "Masters", "year": "1948", "title": "Studies on the Diamagnetic Anisotropy of Crystals", "advisor": "Pauling, Linus; Hughes, Edward Wesley", "url": "https://resolver.caltech.edu/CaltechTHESIS:04062025-023517312", "creators": [ { "name": { "family": "Hoyer", "given": "Horst Walter" }, "id": "Hoyer-Horst-Walter", "display_name": "Hoyer, Horst Walter" } ], "advisors": [ { "name": { "family": "Pauling", "given": "Linus" }, "id": "Pauling-L", "role": "advisor", "display_name": "Pauling, Linus" }, { "name": { "family": "Hughes", "given": "Edward Wesley" }, "id": "Hughes-Edward-Wesley", "role": "advisor", "display_name": "Hughes, Edward Wesley" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/wje8-nt24", "abstract": "Apparatus for the measurement of magnetic anisotropy has been constructed. It is based upon a method first developed by Krishnan in which the torsional force due to the twist on a fine quartz fiber is used to measure the couple acting on the crystal resulting from its anisotropy. By this means the diamagnetic anisotropy of iodoform, arsenic triiodide and potassium chloroplatinite were measured. The results obtained with the last named compound indicated the presence of ferromagnetic impurities. A table of the diamagnetic anisotropy of organic compounds measured to January 1948 has been compiled.
" }, { "name": "Meier, Dale Joseph", "degree": "Masters", "year": "1948", "title": "Studies on the Use of Coulometric and Amperometric Analysis", "advisor": "Swift, Ernest H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04082025-212811851", "creators": [ { "name": { "family": "Meier", "given": "Dale Joseph" }, "id": "Meier-Dale-Joseph", "display_name": "Meier, Dale Joseph" } ], "advisors": [ { "name": { "family": "Swift", "given": "Ernest H." }, "id": "Swift-E-H", "role": "advisor", "display_name": "Swift, Ernest H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/53yb-sn68", "abstract": "I. The coulometric determination of chromates and\r\nvanadates by means of electrolytically generated\r\ncuprous ion has been investigated. For samples\r\nof chromate larger than 170 micrograms, the error\r\nin the determination was less than 0.1 percent.\r\nThe presence of oxygen has been shown to give a\r\npositive error of about 0.5 percent when determining\r\nvanadates. When oxygen was excluded, the\r\nerror in determining 750 micrograms was less than\r\n0.15 percent.
\r\n\r\nII. The use of electrolytically generated argentic\r\nsilver for the determination of manganous ion,\r\ncerous ion and arsenious acid has been investigated\r\nand has been shown to be impractical because of the\r\nslow rate of oxidation by the argentic silver.
\r\n\r\nIII. The determination of Bromine Numbers with electrolytically\r\ngenerated bromine has been investigated.\r\nFor olefins which rapidly add bromine, the use of a\r\n50 percent acetic acid solution of sodium bromide as\r\nthe titration medium has been shown to give good\r\nresults. A means has been proposed for the electrolytic\r\ndetermination of Bromine Numbers for slowly\r\nreacting olefins.
\r\n\r\nIV. An amperometric method for determining the formal\r\npotential of the reaction 2 Cu+++7Br- = 2CuBr2-+Br3-\r\nhas been investigated. The formal potential was\r\nfound to be -.384 v. for solutions 0.017 formal in\r\ncupric ion, 0.44 formal in bromide ion, an 0.7 formal\r\nin sulfuric acid.
" }, { "name": "Winniford, Robert Stanley", "degree": "Masters", "year": "1948", "title": "I. The Synthesis of Methylenecyclobutane from Pentaerythrityl Chloride. II. The Attempted Synthesis of Cyclobutane. III. A Reinvestigation of the Synthesis of Spiroheptanedicarboxylic Acid", "advisor": "Buchman, Edwin Raphael", "url": "https://resolver.caltech.edu/CaltechETD:etd-10062005-083407", "creators": [ { "name": { "family": "Winniford", "given": "Robert Stanley" }, "id": "Winniford-Robert-Stanley", "display_name": "Winniford, Robert Stanley" } ], "advisors": [ { "name": { "family": "Buchman", "given": "Edwin Raphael" }, "id": "Buchman-E-R", "role": "advisor", "display_name": "Buchman, Edwin Raphael" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/ZMYX-Z369", "abstract": "I. The Synthesis of Methylenecyclobutane from Pentaerythrityl Chloride\r\n\r\nA new method for preparing methylenecyclobutane is described in which the starting material is pentaerythrityl tetrachloride. Pentaerythrityl chloride is dechlorinated by zinc dust in the presence of sodium iodide and sodium carbonate, using as solvent either diethylene glycol or acetamide. Reasonable yields are obtained.\r\n\r\nII. The Attempted Synthesis of Cyclobutane\r\n\r\nA synthesis of cyclobutanone through treatment of the methylenecyclobutane-nitrogen trioxide addition compound, with alcoholic potassium hydroxide is not successful.\r\n\r\nThe oxidation of methylenecyclobutane dibromide with potassium permanganate does not yield cyclobutanone.\r\n\r\nIII. A Reinvestigation of the Synthesis of Spiroheptanedicarboxylic Acid\r\n\r\nAn experiment is described in which two mols of malonic ester are condensed with one mol of pentaerythrityl chloride to form spiroheptanetetracarboxylic acid ester. The tetra acid is decarboxylated by heat to afford the dicarboxylic acid. The procedure is a modification of that described in the literature, whereby spiroheptanedicarboxylic acid is prepared from pentaerythrityl bromide.\r\n\r\nA parallel experiment in which pentaerythrityl bromide is condensed with malonic ester is also described.\r\n\r\nThe yields are low in each case." }, { "name": "Brown, Raymond Allen", "degree": "Masters", "year": "1947", "title": "The Formal Potential of the Antimonous-Antimonic Couple in Hydrochloric Acid and a Method for the Determination of Tripositive Antimony", "advisor": "Swift, Ernest H.", "url": "https://resolver.caltech.edu/CaltechETD:etd-10052005-162608", "creators": [ { "name": { "family": "Brown", "given": "Raymond Allen" }, "id": "Brown-Raymond-Allen", "display_name": "Brown, Raymond Allen" } ], "advisors": [ { "name": { "family": "Swift", "given": "Ernest H." }, "id": "Swift-E-H", "role": "advisor", "display_name": "Swift, Ernest H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/MQYW-D781", "abstract": "1. The antimonous-antimonic half cell formal potential has been found to be -0.746 in 3.5 weight formal HC1, -0.784 in 4.5 weight formal HC1, and -0.818 in 6.0 weight formal HC1 when the total antimony concentration is 3.20x10(-2) weight formal.
\r\n\r\n2. The dependence of the formal potential upon total antimony concentration and the ratio Sb(+III)/Sb(+V) has been studied.
\r\n\r\n3. Tripositive antimony has been determined in quantities ranging from 10 to 1,500 micrograms by coulometric titration in hydrochloric acid solutions containing bromide with electrolytically generated bromine using an amperometric end point.
" }, { "name": "Hammock, Edward Woodrow", "degree": "Masters", "year": "1947", "title": "Part I. Iodometric Determination of Copper. Section I. The Use of Thiocyanate. Section II. The Use of Sulfate-Hydrogen Sulfate Buffers. Part II. The Use of Iodine Monochloride End-Point for the Titration of Antimony Using Ceric Sulfate, Potassium Permanganate and Potassium Iodate Solutions. Part III. The Use of Iodine Monochloride as an Indicator in the Titration of Thiocyanate with Permanganate, Iodate and Ceric Sulfate. Part IV. The Distribution of Thallium Between Isopropyl Ether and Hydrochloric Acid", "advisor": "Swift, Ernest H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:05052025-230344625", "creators": [ { "name": { "family": "Hammock", "given": "Edward Woodrow" }, "id": "Hammock-Edward-Woodrow", "display_name": "Hammock, Edward Woodrow" } ], "advisors": [ { "name": { "family": "Swift", "given": "Ernest H." }, "id": "Swift-E-H", "role": "advisor", "display_name": "Swift, Ernest H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/4ykb-rz18", "abstract": "I. This part of the thesis reports a study of some of the limitations\r\nencountered in the iodometric determination of copper. The sulfate-hydrogen\r\nsulfate buffer was introduced for this determination. The permissible pH\r\nrange for this buffer was found to be from about O.5 to 3. It was found\r\nthat the \"oxygen error\" was not noticeable even at the lower limits of this\r\nrange and the end-points were stable enough for a normal titration. Chlorides\r\nand nitrates do not cause serious errors. The procedure using the sulfate\r\nbuffers and thiocyanate was tested against pure copper and copper alloys\r\nwhich contain interfering constituents. The results show that the percentage\r\ndifference from the theoretical is less than one part per thousand.
\r\n\r\nThe effect of adding thiocyanate at various points during the titration,\r\nthe amount required, and the necessity of using pure thiocyanate\r\nwere studied and reported. A study of the difference of the iodide and thiocyanate\r\nend-points was made. It was observed that a small excess of thiosulfate\r\ncould be back titrated. Several wetting agents as well as shellac were\r\ntried in an attempt to protect the cuprous iodide during this back titration.
\r\n\r\nII. A study has been made of the titration of antimony with permanganate,\r\neerie sulfate, and iodate solutions, using the iodine monochloride as\r\nthe indicator. The oxidizing solutions were standardized against Bureau of\r\nStandards arsenious oxide by two methods which agreed within one part per\r\nthousand. In the analysis of an antimony ore, the amount of antimony found\r\nwas about three parts per thousand too high of that present.
\r\n\r\nIII. A study of the titration of thiocyanate has been made in which\r\npermanganate, iodate and eerie sulfate were used as the oxidizing agents,\r\nand iodine monochloride used as the indicator. Results show that iodate\r\ntitration gives results within one part per thousand, the permanganate\r\ntitration within three parts per thousand, and eerie sulfate titration was\r\nnot satisfactory. Potassium thiocyanate can be used as a primary standard.
\r\n\r\nIV. This report is a progress report on the study of the distribution\r\nof thallium between isopropyl ether and hydrochloric acid solution. The\r\nmethod for purifying the ether and the method of the analyzing the ether\r\nand water layers is given. There is not sufficient data to draw any definite\r\nconclusions as to the distribution curve nor the extracted species.
" }, { "name": "Scully, Charles Norman", "degree": "Masters", "year": "1947", "title": "The Chemistry of the 1,3,2 Dioxaphospholanes and Related Compounds", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04012025-175442003", "creators": [ { "name": { "family": "Scully", "given": "Charles Norman" }, "id": "Scully-Charles-Norman", "display_name": "Scully, Charles Norman" } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/b7qb-j098", "abstract": "No abstract." }, { "name": "Thomas, Dudley Watson", "degree": "Masters", "year": "1947", "title": "The Synthesis of Some Aromatic Sulfonic Acids and a Procedure for the Purification of L(-) Leucine", "advisor": "Niemann, Carl G.", "url": "https://resolver.caltech.edu/CaltechTHESIS:03282025-212522311", "creators": [ { "name": { "family": "Thomas", "given": "Dudley Watson" }, "id": "Thomas-Dudley-Watson", "display_name": "Thomas, Dudley Watson" } ], "advisors": [ { "name": { "family": "Niemann", "given": "Carl G." }, "id": "Niemann-C-G", "role": "advisor", "display_name": "Niemann, Carl G." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/ap96-ct83", "abstract": "No abstract." }, { "name": "Wooster, Warren Scriver", "degree": "Masters", "year": "1947", "title": "The Coulometric Titration of Iodide with Electrolytically Generated Bromine Using an Amperometric Endpoint", "advisor": "Swift, Ernest H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04012025-165751766", "creators": [ { "name": { "family": "Wooster", "given": "Warren Scriver" }, "id": "Wooster-Warren-Scriver", "display_name": "Wooster, Warren Scriver" } ], "advisors": [ { "name": { "family": "Swift", "given": "Ernest H." }, "id": "Swift-E-H", "role": "advisor", "display_name": "Swift, Ernest H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/0pc3-me36", "abstract": "No abstract." }, { "name": "Gilman, Theodore Silkman", "degree": "Masters", "year": "1946", "title": "The Study of Nitrocellulose Solutions by Light Scattering Measurements", "advisor": "Badger, Richard McLean", "url": "https://resolver.caltech.edu/CaltechTHESIS:07232025-180526666", "creators": [ { "name": { "family": "Gilman", "given": "Theodore Silkman" }, "id": "Gilman-Theodore-Silkman", "display_name": "Gilman, Theodore Silkman" } ], "advisors": [ { "name": { "family": "Badger", "given": "Richard McLean" }, "id": "Badger-R-M", "role": "advisor", "display_name": "Badger, Richard McLean" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/78w8-vm82", "abstract": "No abstract." }, { "name": "Hall, Luther Axtell Richard", "degree": "Masters", "year": "1946", "title": "Hapten Inhibition of Precipitation of Antisera Homologous to the o-, m-, and p-Azobenoic Acid Groups", "advisor": "Pressman, David", "url": "https://resolver.caltech.edu/CaltechTHESIS:05022025-184306892", "creators": [ { "name": { "family": "Hall", "given": "Luther Axtell Richard" }, "id": "Hall-Luther-Axtell-Richard", "display_name": "Hall, Luther Axtell Richard" } ], "advisors": [ { "name": { "family": "Pressman", "given": "David" }, "id": "Pressman-David", "role": "advisor", "display_name": "Pressman, David" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/1k41-bj64", "abstract": "No abstract." }, { "name": "Mitchell, Fern Wood, Jr.", "degree": "Masters", "year": "1946", "title": "The Reaction Steps in the Conversion of 2,3-Di-p-Toluenesulfonoxybutane to 2,3-Diacetoxybutane", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:04182025-220746373", "creators": [ { "name": { "family": "Mitchell", "given": "Fern Wood, Jr." }, "id": "Mitchell-Fern-Wood", "display_name": "Mitchell, Fern Wood, Jr." } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/r83p-vm58", "abstract": "No abstract." }, { "name": "Bryden, John H.", "degree": "Masters", "year": "1945", "title": "Inhibition of the Precipitin Reaction by Optically Active Haptens and by Derivatives of the Homologous Hapten", "advisor": "Pressman, David", "url": "https://resolver.caltech.edu/CaltechTHESIS:03272025-212241957", "creators": [ { "name": { "family": "Bryden", "given": "John H." }, "id": "Bryden-John-H", "display_name": "Bryden, John H." } ], "advisors": [ { "name": { "family": "Pressman", "given": "David" }, "id": "Pressman-David", "role": "advisor", "display_name": "Pressman, David" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/qq08-w397", "abstract": "The work described in this thesis is part of a program of investigation of immunological reactions being carried out at the California Institute of Technology by Drs. Linus Pauling, David Pressman, Dan H. Campbell, and others. Part I consists largely of the results reported in Paper X of the series \"The Serological Properties of Simple Substances\", published in the Journal of the American Chemical Society.
\r\n\r\nThe phenomenon of hapten inhibition was discovered by Landsteiner, when, to explain the f act that no precipitation occurred with an excess of test azoprotein, he postulated that a reaction did occur between the antibodies and the specific groups of the test antigen, but the products were soluble. A similar effect should be expected if molecules of the simple hapten were present in the solution; i.e., the amount of precipitate formed with optimum amounts of antiserum and antigen should be much less with hapten present than with antiserum and antigen alone. This effect was observed by Landsteiner.
\r\n\r\nIt was also found. that simple compounds having a structure closely similar to that of the homologous hapten would inhibit the precipitation, though to a lesser degree. This fact has been utilized in this investigation as described in Part I, using d- and \u2113-N-(\u03b1-methylbenzyl) succinamic acid, a derivative of N-benzylsuccinamic acid which closely resembles the homologous hapten, succinanilic acid. The affect of various substituents in various positions on the molecule of the homologous hapten is described in Part II.
" }, { "name": "Keilin, Bertram", "degree": "Masters", "year": "1945", "title": "I. The Attempted Synthesis of Cyclobutane from Tetramethylene Dibromide. II. Attempted New Syntheses of 1,3 Cyclobutane Dicarboxylic Acid. III. The Synthesis of Ortho and Meta Arsanilic Acid", "advisor": "Buchman, Edwin Raphael; Pressman, David", "url": "https://resolver.caltech.edu/CaltechTHESIS:04282025-201213151", "creators": [ { "name": { "family": "Keilin", "given": "Bertram" }, "id": "Keilin-Bertram", "display_name": "Keilin, Bertram" } ], "advisors": [ { "name": { "family": "Buchman", "given": "Edwin Raphael" }, "id": "Buchman-E-R", "role": "advisor", "display_name": "Buchman, Edwin Raphael" }, { "name": { "family": "Pressman", "given": "David" }, "id": "Pressman-David", "role": "advisor", "display_name": "Pressman, David" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/ehs6-rt06", "abstract": "No abstract." }, { "name": "Seneker, James Albert", "degree": "Masters", "year": "1945", "title": "The Preparation of Cinchoninic Acids and Related Compounds", "advisor": "Buchman, Edwin Raphael", "url": "https://resolver.caltech.edu/CaltechTHESIS:04162025-230307879", "creators": [ { "name": { "family": "Seneker", "given": "James Albert" }, "id": "Seneker-James-Albert", "display_name": "Seneker, James Albert" } ], "advisors": [ { "name": { "family": "Buchman", "given": "Edwin Raphael" }, "id": "Buchman-E-R", "role": "advisor", "display_name": "Buchman, Edwin Raphael" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/bb4y-j481", "abstract": "No abstract." }, { "name": "Grossberg, Allan Louis", "degree": "Masters", "year": "1944", "title": "Precipitin and Hapten Inhibition Reactions in Serological Systems Involving Simple Chemical Substances of Known Constitution", "advisor": "Pauling, Linus; Pressman, David", "url": "https://resolver.caltech.edu/CaltechTHESIS:04022025-184440823", "creators": [ { "name": { "family": "Grossberg", "given": "Allan Louis" }, "id": "Grossberg-Allan-Louis", "display_name": "Grossberg, Allan Louis" } ], "advisors": [ { "name": { "family": "Pauling", "given": "Linus" }, "id": "Pauling-L", "role": "advisor", "display_name": "Pauling, Linus" }, { "name": { "family": "Pressman", "given": "David" }, "id": "Pressman-David", "role": "advisor", "display_name": "Pressman, David" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/jqt2-xs50", "abstract": "No abstract." }, { "name": "Lemmon, Richard Millington", "degree": "Masters", "year": "1943", "title": "Contributions to the Stereochemistry of Cryptoxanthin and Zeaxanthin", "advisor": "Zechmeister, Laszlo", "url": "https://resolver.caltech.edu/CaltechTHESIS:03062024-211843082", "creators": [ { "name": { "family": "Lemmon", "given": "Richard Millington" }, "id": "Lemmon-Richard-Millington", "display_name": "Lemmon, Richard Millington" } ], "advisors": [ { "name": { "family": "Zechmeister", "given": "Laszlo" }, "id": "Zechmeister-L", "role": "advisor", "display_name": "Zechmeister, Laszlo" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/bbt8-2m16", "abstract": "[Summary]
\r\n\r\n1. The stereoisomerization of cryptoxanthin was studied under the\r\ninfluence of iodine catalysis at room temperature, melting the crystals,\r\nrefluxing and irradiation. Two new stereoisomers of cryptoxanthin were\r\ndetected, one of which, neo-cryptoxanthin U, is adsorbed above all-trans-cryptoxanthin\r\non the Tswett column.
\r\n\r\n2. Molecular extinction curves were taken in the region from 320 to\r\n380 m\u00b5. for all-trans-cryptoxanthin, three of its stereoisomers, and the\r\ncryptoxanthin iodine-catalyzed equilibrium mixture of stereoisomers.
\r\n\r\n3. The stereoisomerization of zeaxanthin was studied under the influence\r\nof melting the crystals, refluxing and irradiation. Three new\r\nstereoisomers of zeaxanthin were detected, two of which appear below all-trans-\r\nzeaxanthin on the Tswett column.
" }, { "name": "Pardee, Arthur Beck", "degree": "Masters", "year": "1943", "title": "Hapten Inhibition of Precipitation of Antisera Specific to the p-Azophenylarsonic Acid Group, the p-(p-Azophenylazo) Phenylarsonic Acid Group, and the p-Azophenylmeylarsinic Acid Group", "advisor": "Pauling, Linus", "url": "https://resolver.caltech.edu/CaltechTHESIS:03192025-182405303", "creators": [ { "name": { "family": "Pardee", "given": "Arthur Beck" }, "id": "Pardee-Arthur-Beck", "display_name": "Pardee, Arthur Beck" } ], "advisors": [ { "name": { "family": "Pauling", "given": "Linus" }, "id": "Pauling-L", "role": "advisor", "display_name": "Pauling, Linus" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/ga0t-gq17", "abstract": "No abstract." }, { "name": "Farquhar, John Percival", "degree": "Masters", "year": "1941", "title": "An Investigation of the Synthesis of \"Pirylene\"", "advisor": "Buchman, Edwin Raphael", "url": "https://resolver.caltech.edu/CaltechTHESIS:02102025-185855030", "creators": [ { "name": { "family": "Farquhar", "given": "John Percival" }, "id": "Farquhar-John-Percival", "display_name": "Farquhar, John Percival" } ], "advisors": [ { "name": { "family": "Buchman", "given": "Edwin Raphael" }, "id": "Buchman-E-R", "role": "advisor", "display_name": "Buchman, Edwin Raphael" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/zgmr-qz28", "abstract": "No abstract." }, { "name": "Fischer, James Rodney", "degree": "Masters", "year": "1941", "title": "The Preparation of Methylene Cyclobutane and Methyl \u0394' Cyclobutane", "advisor": "Buchman, Edwin Raphael", "url": "https://resolver.caltech.edu/CaltechTHESIS:02102025-210337743", "creators": [ { "name": { "family": "Fischer", "given": "James Rodney" }, "id": "Fischer-James-Rodney", "display_name": "Fischer, James Rodney" } ], "advisors": [ { "name": { "family": "Buchman", "given": "Edwin Raphael" }, "id": "Buchman-E-R", "role": "advisor", "display_name": "Buchman, Edwin Raphael" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/mdp4-fq82", "abstract": "No abstract." }, { "name": "Gould, Clark Webster, Jr.", "degree": "Masters", "year": "1940", "title": "Stereochemical Relationships of the Isomeric 3 Chloro 2 Butanols and the 2,-3-Dichlorobutanes", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12082024-135314029", "creators": [ { "name": { "family": "Gould", "given": "Clark Webster, Jr." }, "id": "Gould-Clark-Webster", "display_name": "Gould, Clark Webster, Jr." } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/px28-mz96", "abstract": "No abstract." }, { "name": "Heegaard, Erik Vilhelm", "degree": "Masters", "year": "1940", "title": "Studies on the Relation Between Intake and Urinary Excretion of Thiamin in Normal Man", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:01212025-223602853", "creators": [ { "name": { "family": "Heegaard", "given": "Erik Vilhelm" }, "id": "Heegaard-Erik-Vilhelm", "display_name": "Heegaard, Erik Vilhelm" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/23wg-vy77", "abstract": "No abstract." }, { "name": "Howell, William Jasper, Jr.", "degree": "Masters", "year": "1940", "title": "The Electron Diffraction Investigation of Difluorodibromosilane", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:12162024-192243872", "creators": [ { "name": { "family": "Howell", "given": "William Jasper, Jr." }, "id": "Howell-William-Jasper", "display_name": "Howell, William Jasper, Jr." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/qaq8-fs39", "abstract": "The electron diffraction investigations of the halides of the fourth, fifth, and sixth group elements (1) have shown many interatomic distances to be shorter than those given by Pauling and Huggins\u2019 table of empirical covalent bond radii (2), representing the distances between atoms in pure single bonds in the elements and in other bonds that have considerable ionic character. In the silicon fluorides, which are usually written formally as containing four t-wo-electron bonds, large shortenings occur, and in SiF4, in which the interatomic distance is 5% less than that corresponding to a pure double bond, the explanation of anomalous shortenings applied by Brockway to the fluorochloromethanes (3) breaks down. This laboratory\r\nhas undertaken careful electron diffraction studies of substances showing these unexpected shortenings in the hope that improved explanations may result from a larger accumulation of data. At present, for example, some explanations require postulating sets of resonance structures which altogether give to the atoms reversed orders of electronegativities which disagree with values obtained from electric moments and ionic resonance energies.
" }, { "name": "Moore, Robert Sydney", "degree": "Masters", "year": "1940", "title": "The Association of Silver Ion with Cis and Trans Isomers", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12122024-213633196", "creators": [ { "name": { "family": "Moore", "given": "Robert Sydney" }, "id": "Moore-Robert-Sydney", "display_name": "Moore, Robert Sydney" } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/ef8q-9k62", "abstract": "No abstract." }, { "name": "Russell, Charles Daniel, Jr.", "degree": "Masters", "year": "1940", "title": "Magnetochemical Structural Investigations with Particular Reference to Hemoglobin Equilibria and Compound Formation", "advisor": "Pauling, Linus", "url": "https://resolver.caltech.edu/CaltechTHESIS:01132025-221915071", "creators": [ { "name": { "family": "Russell", "given": "Charles Daniel, Jr." }, "id": "Russell-Charles-Daniel", "display_name": "Russell, Charles Daniel, Jr." } ], "advisors": [ { "name": { "family": "Pauling", "given": "Linus" }, "id": "Pauling-L", "role": "advisor", "display_name": "Pauling, Linus" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/6014-2d85", "abstract": "No abstract." }, { "name": "Cardwell, William Thomas, Jr.", "degree": "Masters", "year": "1939", "title": "Some Properties of the Glass Electrode, Including: The Determination of the Nature of the Asymmetry Potential, The Determination of the Effects of Aging in 0.1 N HCl and 0.1 N KOH, A New Approach to the Theory of the Glass Electrode", "advisor": "Beckman, Arnold O.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12162024-215157917", "creators": [ { "name": { "family": "Cardwell", "given": "William Thomas, Jr." }, "id": "Cardwell-William-Thomas", "display_name": "Cardwell, William Thomas, Jr." } ], "advisors": [ { "name": { "family": "Beckman", "given": "Arnold O." }, "id": "Beckman-Arnold-O", "role": "advisor", "display_name": "Beckman, Arnold O." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/eerx-3896", "abstract": "No abstract." }, { "name": "Gullekson, Ellsworth Eugene", "degree": "Masters", "year": "1939", "title": "Some Fundamental Properties of Asphalts", "advisor": "Beckman, Arnold O.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12112024-234645502", "creators": [ { "name": { "family": "Gullekson", "given": "Ellsworth Eugene" }, "id": "Gullekson-Ellsworth-Eugene", "display_name": "Gullekson, Ellsworth Eugene" } ], "advisors": [ { "name": { "family": "Beckman", "given": "Arnold O." }, "id": "Beckman-Arnold-O", "role": "advisor", "display_name": "Beckman, Arnold O." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/mkd6-4x08", "abstract": "No abstract." }, { "name": "Hepner, Franklin Ross", "degree": "Masters", "year": "1939", "title": "Coordination Complexes of the Mercuric Ion with Cyclohexene", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12102024-211142242", "creators": [ { "name": { "family": "Hepner", "given": "Franklin Ross" }, "id": "Hepner-Franklin-Ross", "display_name": "Hepner, Franklin Ross" } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/6x1m-2793", "abstract": "No abstract." }, { "name": "Hinds, George Putnam, Jr.", "degree": "Masters", "year": "1939", "title": "Volumetric Behavior of Liquid Mixtures of Propane and n-Pentane", "advisor": "Sage, Bruce H.; Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:12122024-234649297", "creators": [ { "name": { "family": "Hinds", "given": "George Putnam, Jr." }, "id": "Hinds-George-Putnam", "display_name": "Hinds, George Putnam, Jr." } ], "advisors": [ { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." }, { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/egvm-qc39", "abstract": "No abstract." }, { "name": "Lavender, Harrison Morton, Jr.", "degree": "Masters", "year": "1939", "title": "The Pressure-Volume-Temperature Relations for the Methane-Decane System in the Liquid and Two-Phase Regions", "advisor": "Sage, Bruce H.; Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:12032024-210703408", "creators": [ { "name": { "family": "Lavender", "given": "Harrison Morton, Jr." }, "id": "Lavender-Harrison-Morton", "display_name": "Lavender, Harrison Morton, Jr." } ], "advisors": [ { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." }, { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/py65-zq39", "abstract": "No abstract." }, { "name": "Smith, Max F.", "degree": "Masters", "year": "1939", "title": "Cation Errors of the Glass Electrode at High Temperatures", "advisor": "Beckman, Arnold O.", "url": "https://resolver.caltech.edu/CaltechTHESIS:01022025-222404716", "creators": [ { "name": { "family": "Smith", "given": "Max F." }, "id": "Smith-Max-F", "display_name": "Smith, Max F." } ], "advisors": [ { "name": { "family": "Beckman", "given": "Arnold O." }, "id": "Beckman-Arnold-O", "role": "advisor", "display_name": "Beckman, Arnold O." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/af6j-8893", "abstract": "No abstract." }, { "name": "Wald, George, Jr.", "degree": "Masters", "year": "1939", "title": "The Phase Behavior of the Methane-Propane-Pentane System", "advisor": "Sage, Bruce H.; Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:01072025-181637917", "creators": [ { "name": { "family": "Wald", "given": "George, Jr." }, "id": "Wald-George", "display_name": "Wald, George, Jr." } ], "advisors": [ { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." }, { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/3kym-qy27", "abstract": "The compositions of the coexisting phases in the methane-n-pentane\r\nsystem for a pressure range from atmospheric to 2500\r\npounds per square inch at temperature of 100\u00b07F., 160\u00b0F. and 220\u00b0F.\r\nwere studied. Coupling these determinations with data from other \r\nsources, gas-liquid equilibrium constants of methane and pentane as\r\nwell as dew point specific volumes were calculated.
\r\n\r\nThe composition of coexisting phases in the methane, propane-n-pentane \r\nsystem for a temperature of 100\u00b0F. and pressures of 200,\r\n500, 1000, 1500, 2000 pounds per square inch in a range of ratios\r\nof propane to n-pentane from 0.05 to 1 was studied. From these data,\r\nvalues for the equilibrium constants of methane, propane and pentane\r\nwere calculated.
" }, { "name": "Axelrod, Joseph", "degree": "Masters", "year": "1938", "title": "Crystal Structure of Tripotassium Cuprocyanide", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:11182024-180405592", "creators": [ { "name": { "family": "Axelrod", "given": "Joseph" }, "id": "Axelrod-Joseph", "display_name": "Axelrod, Joseph" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/y1s0-5g15", "abstract": "No abstract." }, { "name": "Evans, Harry Dean", "degree": "Masters", "year": "1938", "title": "Calorimetric Measurement of Latent Heats of Vaporization of Propane and Normal Pentane and Some Thermodynamic Properties of Normal Pentane", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:11252024-214704859", "creators": [ { "name": { "family": "Evans", "given": "Harry Dean" }, "id": "Evans-Harry-Dean", "display_name": "Evans, Harry Dean" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/4gpy-yp06", "abstract": "Measurements of the latent heat of vaporization of\r\npropane and normal pentane were made with an adiabatic\r\nbomb calorimeter. The temperature range for propane was from\r\n103.4\u00b0 F. to 163.2\u00b0 F. Normal pentane measurements were\r\nfrom 103.7 to 200\u00b0 Fahrenheit. A description of the\r\napparatus and the method of calculation will be found in\r\npart 1 of this paper.
\r\n\r\nIn the second section of this paper some of the thermodynamic \r\nproperties of n-pentane in the superheated gas\r\nregion were calculated. Included in this section are\r\ntabulated values of entropy, enthalpy, residual volume, and\r\nheat capacity.
" }, { "name": "Hatcher, John Burton", "degree": "Masters", "year": "1938", "title": "Rates of Absorption and Description of Butane in Crystal Oil and Some Considerations in the Circulation of Diffusion Constants", "advisor": "Lacey, William Noble; Sage, Bruce H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12032024-183651455", "creators": [ { "name": { "family": "Hatcher", "given": "John Burton" }, "id": "Hatcher-John-Burton", "display_name": "Hatcher, John Burton" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" }, { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/grzk-a017", "abstract": "No abstract." }, { "name": "Nellis, Donald Charles", "degree": "Masters", "year": "1938", "title": "The Pressure-Volume-Temperature Relationships of Propane", "advisor": "Sage, Bruce H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12102024-214146715", "creators": [ { "name": { "family": "Nellis", "given": "Donald Charles" }, "id": "Nellis-Donald-Charles", "display_name": "Nellis, Donald Charles" } ], "advisors": [ { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/0vyq-6m71", "abstract": "No abstract." }, { "name": "Nysewander, Cecil Wright", "degree": "Masters", "year": "1938", "title": "Phase Equilibria in the Propane-Butane System", "advisor": "Sage, Bruce H.; Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:11252024-191022116", "creators": [ { "name": { "family": "Nysewander", "given": "Cecil Wright" }, "id": "Nysewander-Cecil-Wright", "display_name": "Nysewander, Cecil Wright" } ], "advisors": [ { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." }, { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/77pd-9657", "abstract": "No abstract." }, { "name": "Lotzkar, Harry", "degree": "Masters", "year": "1937", "title": "The Thermal Cis-Transisomerization of Cinnamic Acid Catalyzed by Iodine", "advisor": "Dickinson, Roscoe Gilkey", "url": "https://resolver.caltech.edu/CaltechTHESIS:03182025-211218731", "creators": [ { "name": { "family": "Lotzkar", "given": "Harry" }, "id": "Lotzkar-Harry", "display_name": "Lotzkar, Harry" } ], "advisors": [ { "name": { "family": "Dickinson", "given": "Roscoe Gilkey" }, "id": "Dickinson-R-G", "role": "advisor", "display_name": "Dickinson, Roscoe Gilkey" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/53cg-va67", "abstract": "In this investigation, a study was made of the kinetics and mechanism suggested by the kinetics of the iodine-catalyzed thermal conversion of cis-cinnamic acid to trans-cinnamic acid. Berthoud and Urech studied the kinetics of the iodine-sensitized photo-chemical conversion of cis-cinnamic acid to trans-cinnamic acid and proposed a mechanism for it. They found that the reaction rate is given by
\r\n[Equation. See abstract in scanned thesis for details]
\r\nThey suggested the following mechanism for the photochemical conversion:
\r\nI2 + h\u2713 \u2192 2I
\r\nC + I \u2192 CI
\r\nCI \u2192 TI
\r\nTI \u2192 T + I
\r\n2I \u2192 I2
\r\nwhere C and T denote cis-cinnamic acid and trans-cinnamic acid, resp. Structurally, the conversion is represented as follows:
\r\n\r\n[Formula. See abstract in scanned thesis for details]
" }, { "name": "Vermeulen, Theodore", "degree": "Masters", "year": "1937", "title": "Calorimetric Measurements of Some Hydrocarbons", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:11052024-220419432", "creators": [ { "name": { "family": "Vermeulen", "given": "Theodore" }, "id": "Vermeulen-Theodore", "display_name": "Vermeulen, Theodore" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/bbv4-2x12", "abstract": "No abstract." }, { "name": "Davies, James Allman", "degree": "Masters", "year": "1936", "title": "The Thermodynamic Properties of an Ethane Crystal Oil Mixture", "advisor": "Sage, Bruce H.", "url": "https://resolver.caltech.edu/CaltechETD:etd-04232008-153555", "creators": [ { "name": { "family": "Davies", "given": "James Allman" }, "id": "Davies-James-Allman", "display_name": "Davies, James Allman" } ], "advisors": [ { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/WN7F-W289", "abstract": "No abstract." }, { "name": "Deahl, Thomas Jay", "degree": "Masters", "year": "1936", "title": "The Oxidation Potential of Cobaltous-Cobaltic Salts in Nitric Acid Solution", "advisor": "Noyes, Arthur A.", "url": "https://resolver.caltech.edu/CaltechETD:etd-04232008-095756", "creators": [ { "name": { "family": "Deahl", "given": "Thomas Jay" }, "id": "Deahl-Thomas-Jay", "display_name": "Deahl, Thomas Jay" } ], "advisors": [ { "name": { "family": "Noyes", "given": "Arthur A." }, "id": "Noyes-A-A", "role": "advisor", "display_name": "Noyes, Arthur A." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/BGPA-XC19", "abstract": "No abstract." }, { "name": "Inman, Byron Noll", "degree": "Masters", "year": "1936", "title": "The Viscosities for Hydrocarbon Systems. The Effect of Composition and Pressure Upon the Viscosity for a Three Component Hydrocarbon System", "advisor": "Sage, Bruce H.; Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:11072024-190004643", "creators": [ { "name": { "family": "Inman", "given": "Byron Noll" }, "id": "Inman-Byron-Noll", "display_name": "Inman, Byron Noll" } ], "advisors": [ { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." }, { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/mqe2-r454", "abstract": "No abstract." }, { "name": "Larsen, Delmar H.", "degree": "Masters", "year": "1936", "title": "Photochemical Intermittency and the Photochlorination of Tetrachloroethylene in Carbon Tetrachloride Solution", "advisor": "Dickinson, Roscoe Gilkey", "url": "https://resolver.caltech.edu/CaltechTHESIS:04012025-153556923", "creators": [ { "name": { "family": "Larsen", "given": "Delmar H." }, "id": "Larsen-Delmar-H", "display_name": "Larsen, Delmar H." } ], "advisors": [ { "name": { "family": "Dickinson", "given": "Roscoe Gilkey" }, "id": "Dickinson-R-G", "role": "advisor", "display_name": "Dickinson, Roscoe Gilkey" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/qndx-yz67", "abstract": "No abstract." }, { "name": "Mendenhall, William Rees", "degree": "Masters", "year": "1936", "title": "Studies of Some Properties of Hydrocarbons", "advisor": "Lacey, William Noble; Sage, Bruce H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:11132024-183212993", "creators": [ { "name": { "family": "Mendenhall", "given": "William Rees" }, "id": "Mendenhall-William-Rees", "display_name": "Mendenhall, William Rees" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" }, { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/g0ff-aq67", "abstract": "No abstract." }, { "name": "Skinner, Davis Ayres", "degree": "Masters", "year": "1936", "title": "Butadiene from the Pyrolysis of 2,3-Dichlorobutane", "advisor": "Lacey, William Noble; Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:12052017-105033167", "creators": [ { "name": { "family": "Skinner", "given": "Davis Ayres" }, "id": "Skinner-Davis-Ayres", "display_name": "Skinner, Davis Ayres" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" }, { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "co-advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/ZX4V-1K10", "abstract": "Summary:
\r\n\r\n1. A satisfactory laboratory apparatus and method for\r\npreparing butadiene from 2,3-dichlorobutane, by\r\npassing over BaCl2 on pumice, at temperatures\r\nranging from 500-600\u00b0C., has been described.
\r\n\r\n2. An analytical method for the products is developed\r\nusing maleic anhydride to absorb butadiene, 87 percent\r\nsulfuric acid for butenes, and fractional distillation\r\nfor the separation of chlorobutenes from the butadiene.
\r\n\r\n3. Butadiene, chlorobutene, butene, lower hydrocarbons,\r\nand hydrochloric acid have been shown to result from \r\nthe pyrolysis of 2,3-dichlorobutane over BaCl2.
\r\n\r\n4. Conditions are described for obtaining yield, of\r\nbutadiene as high as 57.6% and optimum conditions\r\nare predicted. The higher yields here obtained\r\nexceeding those found in the literature, for this \r\npyrolysis.
" }, { "name": "Backus, Harrison Stout", "degree": "Masters", "year": "1935", "title": "Specific Heats of Some Hydrocarbon Solutions", "advisor": "Lacey, William Noble; Sage, Bruce H.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10222024-211548740", "creators": [ { "name": { "family": "Backus", "given": "Harrison Stout" }, "id": "Backus-Harrison-Stout", "display_name": "Backus, Harrison Stout" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" }, { "name": { "family": "Sage", "given": "Bruce H." }, "id": "Sage-B-H", "role": "advisor", "display_name": "Sage, Bruce H." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/r6xy-6p78", "abstract": "No abstract." }, { "name": "Bertram, Edward Austen", "degree": "Masters", "year": "1935", "title": "The Rate of Solution of Methane in a Hydrocarbon Oil Held in the Pores of Sand", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:10072024-163108746", "creators": [ { "name": { "family": "Bertram", "given": "Edward Austen" }, "id": "Bertram-Edward-Austen", "display_name": "Bertram, Edward Austen" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/4zm6-na51", "abstract": "No abstract." }, { "name": "Gross, Siegfried Theodore", "degree": "Masters", "year": "1935", "title": "The Raman Spectra of Some Volatile Fluorides", "advisor": "Yost, Don M.", "url": "https://resolver.caltech.edu/CaltechTHESIS:10292024-153525943", "creators": [ { "name": { "family": "Gross", "given": "Siegfried Theodore" }, "id": "Gross-Siegfried-Theodore", "display_name": "Gross, Siegfried Theodore" } ], "advisors": [ { "name": { "family": "Yost", "given": "Don M." }, "id": "Yost-D-M", "role": "advisor", "display_name": "Yost, Don M." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/wdvh-m211", "abstract": "No abstract." }, { "name": "Nies, Nelson Perry", "degree": "Masters", "year": "1935", "title": "The Effect of the Wave Length on the Photochemical Decomposition of Ethylene Iodide in Carbon Tetrachloride Solution", "advisor": "Dickinson, Roscoe Gilkey", "url": "https://resolver.caltech.edu/CaltechTHESIS:10102024-174620263", "creators": [ { "name": { "family": "Nies", "given": "Nelson Perry" }, "id": "Nies-Nelson-Perry", "display_name": "Nies, Nelson Perry" } ], "advisors": [ { "name": { "family": "Dickinson", "given": "Roscoe Gilkey" }, "id": "Dickinson-R-G", "role": "advisor", "display_name": "Dickinson, Roscoe Gilkey" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/e8jg-kq17", "abstract": "No abstract." }, { "name": "Simmons, Norwood Lee", "degree": "Masters", "year": "1935", "title": "The Mercury-Sensitized Photochemical Decomposition of Arsine", "advisor": "Beckman, Arnold O.", "url": "https://resolver.caltech.edu/CaltechTHESIS:11012024-145403091", "creators": [ { "name": { "family": "Simmons", "given": "Norwood Lee" }, "id": "Simmons-Norwood-Lee", "display_name": "Simmons, Norwood Lee" } ], "advisors": [ { "name": { "family": "Beckman", "given": "Arnold O." }, "id": "Beckman-Arnold-O", "role": "advisor", "display_name": "Beckman, Arnold O." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/rhqt-7h26", "abstract": "No abstract." }, { "name": "Doescher, Russell Nimtz", "degree": "Masters", "year": "1934", "title": "The Magnetic Susceptibilities of the Metal Ketyls", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:09182024-174614735", "creators": [ { "name": { "family": "Doescher", "given": "Russell Nimtz" }, "id": "Doescher-Russell-Nimtz", "display_name": "Doescher, Russell Nimtz" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/3rap-7h11", "abstract": "No abstract." }, { "name": "Frieman, Rubin Harold", "degree": "Masters", "year": "1934", "title": "I. Oxonium Compound Formation by Alcohol in Aqueous Solution. II. The Hydration of Acetylene", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:02082017-133402744", "creators": [ { "name": { "family": "Frieman", "given": "Rubin Harold" }, "id": "Frieman-Rubin-Harold", "display_name": "Frieman, Rubin Harold" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/YBHJ-YH98", "abstract": "Part I
\r\n\r\n1. The distribution of alcohol between benzene and\r\naqueous solutions of (1) sulfuric acid, (2) sodium sulfate,\r\nand (3) mixtures of perchloric acid and sodium perchlorate\r\nhas been studied.
\r\n\r\n2. Apparent values of equilibrium constants for the\r\nformation of oxonium salts in aqueous solutions have been\r\ncalculated.
\r\n\r\nPart II
\r\n\r\n\r\n1. It has been established that oxygen exerts an\r\ninhibiting effect in the formation of the complex compounds \r\nof mercury which catalyze the hydration of acetylene.
\r\n\r\n2. The hydration of acetylene has been shown to\r\nbe of first order with respect to acetylene.
\r\n\r\n3. The conditions for the rapid determination of\r\nacetylene in the presence of oxygen by the bromate-bromide \r\nmethod have been determined.
\r\n\r\n\r\n\r\n" }, { "name": "Hooper, Duncan-Leverich", "degree": "Masters", "year": "1934", "title": "The Wagner Turbidimeter as an Instrument for the Determination of Specific Surface and Particle-Size Distribution of Portland Cement. An Instrument for the Measurement of the Thermal Conductivity of Water, and for the Investigation of Phenomena in Heat Transfer in the Liquid and at the Liquid-Solid Boundary", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:10162024-011149839", "creators": [ { "name": { "family": "Hooper", "given": "Duncan-Leverich" }, "id": "Hooper-Duncan-Leverich", "display_name": "Hooper, Duncan-Leverich" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/jve9-ps32", "abstract": "The Wagner Turbidimeter has given promise of being a suitable instrument for use in the determination of the surface exposed by the particles in samples of Portland cement. Since the extent of this surface is an important factor in controlling or predicting the behavior of cements in the production of concrete, a simple but accurate method for its determination is highly desirable in connection with investigations and acceptance tests.
\r\n\r\nThe purpose of the present investigation was to make a critical study of the advantages and short-comings of this instrument and to recommend modifications of apparatus or procedure which might improve its performance. The various steps in the procedure and the possible sources of uncertainty and error in the results have been examined in detail.
\r\n\r\nSeveral modifications of the apparatus have been found beneficial and numerous changes in the procedure to be used have been found essential for obtaining satisfactory results. With the suggested improvements, the instrument appears to offer a reasonably satisfactory method for routine\r\ntests of specific surface (usually expressed as square centimeters of surface per gram of cement), and also for approximation of the distribution of the sizes of the particles of the cement.
\r\n\r\nAlthough the results are not entirely accurate and reproducible, they are within useful limits and the instrument is recommended for use in acceptance test work on specific surface measurement, until a more accurate method, utilizing instruments of reasonable cost and with simple operating procedure has been developed. For research or investigational purposes, where cements of varying chemical and physical characteristics (including optical properties) are -being studied, it is believed that the turbidimeter method may not be sufficiently accurate and should not be depended upon, unless special precautions are observed and great care taken in the work.
" }, { "name": "Kennedy, Edwin Russell", "degree": "Masters", "year": "1934", "title": "The Decomposition of Di-o-Tolyliodonium Iodide", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:09202024-181837097", "creators": [ { "name": { "family": "Kennedy", "given": "Edwin Russell" }, "id": "Kennedy-Edwin-Russell", "display_name": "Kennedy, Edwin Russell" } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/7da9-yc49", "abstract": "No abstract." }, { "name": "Offner, Franklin Faller", "degree": "Masters", "year": "1934", "title": "A Determination of the Parameter for Hauerite", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:09222017-164814870", "creators": [ { "name": { "family": "Offner", "given": "Franklin Faller" }, "id": "Offner-Franklin-Faller", "display_name": "Offner, Franklin Faller" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/TKAX-JE95", "abstract": "In Part I, after a discussion of covalency and covalent radii, a brief review of the work of Bragg on pyrite, and Ewald and Friedrich on pyrite and hauerite, with an evaluation of accuracy, is given. The Laue method for crystal analysis is described, and the theory outlined.
\r\n\r\nPart II is devoted to the description of a new parameter determination for hauerite carried out by the writer. As a result of this determination, the parameter has been fixed at u = 0.4012 \u00b1 0.0004, giving a covalent sulfur radius of 1.043 \u00c5.
" }, { "name": "Schaafsma, Jan Gerard", "degree": "Masters", "year": "1934", "title": "Some Studies on the Thermodynamic Relations in Multi-Component Systems", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:09242024-152737146", "creators": [ { "name": { "family": "Schaafsma", "given": "Jan Gerard" }, "id": "Schaafsma-Jan-Gerard", "display_name": "Schaafsma, Jan Gerard" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/8s06-q590", "abstract": "No abstract." }, { "name": "Kircher, Charles Edmund Jr.", "degree": "Masters", "year": "1933", "title": "Solubility of Natural Gas in Various Crude Oils and Preparation of Pure Methane from Natural Gas", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:05122017-093006165", "creators": [ { "name": { "family": "Kircher", "given": "Charles Edmund Jr." }, "id": "Kircher-Charles-Edmund-Jr.", "display_name": "Kircher, Charles Edmund Jr." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/FWDP-HK80", "abstract": "The work reported in this paper is a continuation of experiments begun and carried out by B.H. Sage, and described in his thesis for the Masters degree C.I.T. 1931. The object of the research was to determine as quantitatively as possible the solubility of natural gas in various crude oils, as it was known that by dissolving natural gas in crude oil, the physical properties of the oil could be changed in such a way as to make possible greater recovery of the crude oil from the underground formation. As pointed out by Mr. Sage, the solubility figures presented in his thesis had to be arrived\r\nat by a method of approximation as he was then not experimentally able to measure the change in liquid volume resulting from dissolved gas. In order to make possible more accurate calculation of gas solubility, apparatus was designed and installed for directly measuring the change in volume of the crude oil which occurred as a result of dissolved gas. Other changes were made in the equipment as first set up by Mr. Sage, which were designed to increase accuracy and speed in carrying out the experiments. These changes will be discussed in the main body of this report.\r\n" }, { "name": "Lyons, Ernest Herbert, Jr.", "degree": "Masters", "year": "1933", "title": "The Photo-Oxidation of Carbon Tetrachloride", "advisor": "Dickinson, Roscoe Gilkey", "url": "https://resolver.caltech.edu/CaltechTHESIS:02282017-090332720", "creators": [ { "name": { "family": "Lyons", "given": "Ernest Herbert, Jr." }, "id": "Lyons-Ernest-Herbert-Jr.", "display_name": "Lyons, Ernest Herbert, Jr." } ], "advisors": [ { "name": { "family": "Dickinson", "given": "Roscoe Gilkey" }, "id": "Dickinson-R-G", "role": "advisor", "display_name": "Dickinson, Roscoe Gilkey" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/ZC4V-5J32", "abstract": "1. It has been shown that carbon tetrachloride\r\nis not decomposed by light of wavelength 2537\r\n\u00e5ngstroms.
\r\n\r\n2. It has been shown that light of wavelength\r\n2537 \u00e5ngstroms produces an oxidation of carbon\r\ntetrachloride according to the reaction
\r\n\r\nCCl4 + \u00bdO2 \u2192 COCl2 + Cl2\r\n\r\nIt has been shown that one molecule of carbon\r\ntetrachloride is decomposed per quantum of light\r\nabsorbed. A possible mechanism for this reaction\r\nhas been given.
\r\n\r\n3. The difficulty of purifying carbon\r\ntetrachloride for photochemical work has been\r\npointed out.
\r\n\r\n4. Evidence suggesting a photochemical \r\nhydrolysis of carbon tetrachloride has been\r\ngiven.
\r\n\r\n" }, { "name": "Prater, Arthur Nickolas", "degree": "Masters", "year": "1933", "title": "The Reaction Between Oxygen and 2-Butene", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:03012017-102431032", "creators": [ { "name": { "family": "Prater", "given": "Arthur Nickolas" }, "id": "Prater-Arthur-Nickolas", "display_name": "Prater, Arthur Nickolas" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/NNVD-0F26", "abstract": "2-Butene has been found to react with oxygen at temperatures\r\nof 375\u00b0 to 500\u00b0. At the higher temperatures, polymerization as well as\r\noxidation takes place. The products of the reaction which have been\r\nidentified are acetaldehyde, glyoxal and/or glycollic aldehyde,\r\n1,3-butadiene, acid, peroxide and an olefin oxide. The simplest explanation of the reactions occurring involve both hydroxylation and peroxide formation as primary products." }, { "name": "Wilson, Chester Eugene", "degree": "Masters", "year": "1933", "title": "Chlorohydrins and Oxides of the Isomeric-2-Butenes", "advisor": "Lucas, Howard J.", "url": "https://resolver.caltech.edu/CaltechTHESIS:01302017-152800940", "creators": [ { "name": { "family": "Wilson", "given": "Chester Eugene" }, "id": "Wilson-Chester-Eugene", "display_name": "Wilson, Chester Eugene" } ], "advisors": [ { "name": { "family": "Lucas", "given": "Howard J." }, "id": "Lucas-H-J", "role": "advisor", "display_name": "Lucas, Howard J." } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/BCPN-QV04", "abstract": "1. A method is given for the preparation of 2-butene chlorohydrin by the addition of acetic acid to a mixture of calcium hypochlorite and butene at -10\u00b0C.
\r\n\r\n2. A convenient method is given for the preparation of large amounts of butene oxide by dropping butene chlorohydrin on hot concentrated potassium hydroxide solution.
\r\n\r\n3. The fractional distillation of the isomeric chlorohydrins of the 2-butenes is described.
\r\n\r\n4. The fractional distillation of the isomeric 2-butene oxides is described.
\r\n\r\n5. The physical properties of the fractions of 2-butene chlorohydrin and of the fractions of 2-butene oxide are given.
\r\n\r\n6. The approximate values are given for the hydrolysis rate of the two fractions of 2-butene chlorohydrin.
" }, { "name": "Ellis, Emory Leon", "degree": "Masters", "year": "1932", "title": "The Rate of Decomposition of Ethyl Hypochlorite", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-04262004-144509", "creators": [ { "name": { "family": "Ellis", "given": "Emory Leon" }, "id": "Ellis-Emory-Leon", "display_name": "Ellis, Emory Leon" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/3DTD-RK20", "abstract": "No Abstract." }, { "name": "Gunderson, Norman Robert", "degree": "Masters", "year": "1932", "title": "Losses of Sulphur from the Sulphate Paper Pulp Process", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:09172024-215758337", "creators": [ { "name": { "family": "Gunderson", "given": "Norman Robert" }, "id": "Gunderson-Norman-Robert", "display_name": "Gunderson, Norman Robert" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/pfqn-0q59", "abstract": "No abstract." }, { "name": "Launer, Herbert Franz", "degree": "Masters", "year": "1932", "title": "The Kinetics of the Reaction between Potassium Permanganate and Oxalic Acid", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:09112024-214755981", "creators": [ { "name": { "family": "Launer", "given": "Herbert Franz" }, "id": "Launer-Herbert-Franz", "display_name": "Launer, Herbert Franz" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/879d-f064", "abstract": "No abstract." }, { "name": "Morris, Ross Elliott", "degree": "Masters", "year": "1932", "title": "The Reaction between Oxygen and 2-Butene", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:09112024-183709851", "creators": [ { "name": { "family": "Morris", "given": "Ross Elliott" }, "id": "Morris-Ross-Elliott", "display_name": "Morris, Ross Elliott" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/b8c7-6y32", "abstract": "No abstract." }, { "name": "Robinson, Roger Theophilus", "degree": "Masters", "year": "1932", "title": "An Investigation of the Characteristics of Dennisite and its Components", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:09112024-222645094", "creators": [ { "name": { "family": "Robinson", "given": "Roger Theophilus" }, "id": "Robinson-Roger-Theophilus", "display_name": "Robinson, Roger Theophilus" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/8y4q-7n17", "abstract": "No abstract." }, { "name": "Welge, Henry", "degree": "Masters", "year": "1932", "title": "The Hydration of Iso-Butylene to Tertiary Butyl Alcohol", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:09122024-153530269", "creators": [ { "name": { "family": "Welge", "given": "Henry" }, "id": "Welge-Henry", "display_name": "Welge, Henry" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/ny6a-0d95", "abstract": "No abstract." }, { "name": "Hill, Earl S.", "degree": "Masters", "year": "1931", "title": "Diffusion of Hydrocarbon Gases into Oils and Oil Sands", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:08262024-215224028", "creators": [ { "name": { "family": "Hill", "given": "Earl S." }, "id": "Hill-Earl-S", "display_name": "Hill, Earl S." } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/ee00-6h79", "abstract": "No abstract." }, { "name": "Hoeppel, Raymond Winfield", "degree": "Masters", "year": "1931", "title": "Denitrification of Chuquicamata Copper Solutions", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:09032024-210245990", "creators": [ { "name": { "family": "Hoeppel", "given": "Raymond Winfield" }, "id": "Hoeppel-Raymond-Winfield", "display_name": "Hoeppel, Raymond Winfield" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/sc6j-cf26", "abstract": "No abstract." }, { "name": "Sage, Bruce Hornbrook", "degree": "Masters", "year": "1931", "title": "The Determination of the Solubility of Natural Gases in Crude Oils", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:09062024-154506775", "creators": [ { "name": { "family": "Sage", "given": "Bruce Hornbrook" }, "id": "Sage-Bruce-Hornbrook", "display_name": "Sage, Bruce Hornbrook" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/0xt4-mr86", "abstract": "No abstract." }, { "name": "Shirley, Howard Emerson", "degree": "Masters", "year": "1931", "title": "The Progress of the Reactions in a Portland Cement Kiln, and A Method for the Production of Anhydrous Sodium Sulfate", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:09062024-185453476", "creators": [ { "name": { "family": "Shirley", "given": "Howard Emerson" }, "id": "Shirley-Howard-Emerson", "display_name": "Shirley, Howard Emerson" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/vzj2-x573", "abstract": "No abstract." }, { "name": "Pohl, Wadsworth Egmont", "degree": "Masters", "year": "1930", "title": "Studies on the Drying of Sugar Pine Lumber", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:08272024-214529660", "creators": [ { "name": { "family": "Pohl", "given": "Wadsworth Egmont" }, "id": "Pohl-Wadsworth-Egmont", "display_name": "Pohl, Wadsworth Egmont" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/j4pa-kg61", "abstract": "No abstract." }, { "name": "Scoville, Loren P.", "degree": "Masters", "year": "1930", "title": "Experimental Studies of Oil Flow through Sands", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:08262024-210019529", "creators": [ { "name": { "family": "Scoville", "given": "Loren P." }, "id": "Scoville-Loren-P.", "display_name": "Scoville, Loren P." } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/byrq-2c70", "abstract": "No abstract." }, { "name": "Stapp, Frederick Pearce", "degree": "Masters", "year": "1930", "title": "The Rate of Diffusion of Methane in Liquid Hydrocarbons", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechTHESIS:09032024-184023419", "creators": [ { "name": { "family": "Stapp", "given": "Frederick Pearce" }, "id": "Stapp-Frederick-Pearce", "display_name": "Stapp, Frederick Pearce" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/jg9v-v519", "abstract": "No abstract." }, { "name": "Stenzel, Richard Werner", "degree": "Masters", "year": "1930", "title": "The Heat of Wetting of Silica Gel by Petroleum Hydrocarbons", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:08262024-204024746", "creators": [ { "name": { "family": "Stenzel", "given": "Richard Werner" }, "id": "Stenzel-Richard-Werner", "display_name": "Stenzel, Richard Werner" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/5fgq-2s27", "abstract": "No abstract." }, { "name": "Urmston, Joseph Winchester", "degree": "Masters", "year": "1930", "title": "Activity of Hydrochloric Acid in the Presence of Added Salts", "advisor": "Bates, Stuart Jeffery", "url": "https://resolver.caltech.edu/CaltechTHESIS:02272024-214831724", "creators": [ { "name": { "family": "Urmston", "given": "Joseph Winchester" }, "id": "Urmston-Joseph-Winchester", "display_name": "Urmston, Joseph Winchester" } ], "advisors": [ { "name": { "family": "Bates", "given": "Stuart Jeffery" }, "id": "Bates-Stuart-Jeffery", "role": "advisor", "display_name": "Bates, Stuart Jeffery" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/3609-3p39", "abstract": "[Summary] The effect of added salts without a common ion upon the\r\nactivity of hydrochloric acid has been determined by measurements\r\nof the electromotive force of cells of the type
\r\n\r\nH2, HCl c1m + NaClO4 c2m, AgCl+Ag,
\r\n\r\nwhere e1 = 0.25 m, 0.1 m, 0.05 m and 0.005 m, and for values of \r\nc1 + c2 up to 1 m.
\r\n\r\nSimilar cells substituting KClO4 for NaClO4 were investigated \r\nover a concentration range which, however, was rather restricted due to \r\nthe limited solubility of potassium perchlorate.
\r\n\r\nThe results show that the activity coefficient of hydrochloric \r\nacid in the presence of the added salts without a common ion is, at \r\nsimilar ionic strengths, somewhat less than that of the pure acid, that \r\nis at a fixed concentration of acid the activity goes thru a minimum \r\nwith increasing ionic strength and then increases in a manner which is \r\nroughly similar to that observed for pure acid solutions.
\r\n\r\nThe ion attraction theory is discussed qualitatively. In \r\ndilute solutions it undoubtedly accounts for the facts upon a relatively \r\nsimple physical basis, but its extension to more concentrated solutions \r\nresulting in a two constant equation and the application of this to mixtures \r\nof electrolytes is probably largely empirical in nature.
\r\n\r\nThe fact that the activity coefficient of hydrochloric acid \r\nin its own pure solution, and in solution in the presence of a salt without a \r\ncommon ion including solutions which contain no acid, and whose \r\nproperties therefore depend entirely upon those of the added salt goes \r\nthru a minimum. with increasing ionic strength shows that this electrolyte \r\nis very readily \"salted out\". This behaviour is probably associated \r\nwith the unique structure of the hydrogen ion in that it has no electron \r\norbits to be deformed in the strong electrical field prevailing \r\nin concentrated solutions.
\r\n\r\nThe principle of linear variation of logo \u03b1 with the concentration\r\nof acid at constant total molality applies to mixtures of \r\nthe acid and sodium perchlorate in dilute solutions, but does not \r\nhold at concentrations from 0.25 m. to 1.0 m. In this last respect \r\nthe behaviour is different from that observed when a chloride is the \r\nadded salt.
\r\n\r\nThe results of this investigation are discussed in terms of \r\nthe effect of added salt upon the solubility of hydrochloric acid and \r\nits change in solubility with added salt is compared at similar initial \r\nsolubilities with those of thallous chloride and potassium perchlorate. \r\nFor hydrochloric acid in the presence of an added salt \r\nwithout a common ion, a solubility curve of a new type is disclosed, \r\nin that its solubility increases to a maximum and then decreases as \r\nthe concentration of added salt is increased.
" }, { "name": "Scudder, Nathan Frost", "degree": "Masters", "year": "1928", "title": "Further Studies Toward the Prevention of Brown Stain in Sugar Pine Lumber", "advisor": "Lacey, William Noble", "url": "https://resolver.caltech.edu/CaltechETD:etd-03072005-130729", "creators": [ { "name": { "family": "Scudder", "given": "Nathan Frost" }, "id": "Scudder-Nathan-Frost", "display_name": "Scudder, Nathan Frost" } ], "advisors": [ { "name": { "family": "Lacey", "given": "William Noble" }, "id": "Lacey-W-N", "role": "advisor", "display_name": "Lacey, William Noble" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/NFF4-VX56", "abstract": "Since this report is a continuation of the work described by Mr. Steinour in his thesis, and rightly should accompany that thesis, the reader is referred directly to it for a description of the nature of the problem, the existing knowledge pertaining to it before Mr. Steinour started his work, and the facts concerning the stain and means of preventing it that he discovered. The experimental method he developed for making small scale kiln drying experiments was followed exactly in every detail, including the use of the same drying oven and instruments, and the same assumptions in calculating the data taken, so that the results described herein should be entirely comparable." }, { "name": "Bilicke, Albert Constant", "degree": "Masters", "year": "1927", "title": "The Space-Group and Molecular Symmetry of Beta-Benzenehexabromide and Hexachloride", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-12092004-113152", "creators": [ { "name": { "family": "Bilicke", "given": "Albert Constant" }, "id": "Bilicke-Albert-Constant", "display_name": "Bilicke, Albert Constant" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/KRQ9-E936", "abstract": "The small crystallographic symmetry of most organic compounds has limited the determination of their structures by crystal-structure researches. Yet many problems of structural organic chemistry can be so answered. We have determined the space-group and molecular symmetry of \u03b2-benzene hexabromide and hexachloride, and have obtained information of value in the interpretation of the geometrical isomerism of these compounds.
\r\n\r\nBoth benzene hexabromide, C6H6Br6 and benzene hexacholoride, C6H6Cl6, crystallize in two modifications differing markedly in physical properties. The monoclinic forms, designated alpha, have been assigned the \"trans\" configuration. The \"cis\" or beta modification of the hexabromide crystallizes in the cubic system, while the hexachloride has been reported to form hexagonal crystals which are pseudocubic. Our investigation has been restricted to the beta forms.
\r\n" }, { "name": "Pomeroy, Richard Durant", "degree": "Masters", "year": "1927", "title": "Use of Adsorbents in Natural Gas Analysis", "advisor": "Millikan, Robert Andrews", "url": "https://resolver.caltech.edu/CaltechETD:etd-12272004-135856", "creators": [ { "name": { "family": "Pomeroy", "given": "Richard Durant" }, "id": "Pomeroy-Richard-Durant", "display_name": "Pomeroy, Richard Durant" }, { "name": { "family": "Campbell", "given": "John Stuart" }, "id": "Campbell-John-Stuart", "display_name": "Campbell, John Stuart" } ], "advisors": [ { "name": { "family": "Millikan", "given": "Robert Andrews" }, "id": "Millikan-R-A", "role": "advisor", "display_name": "Millikan, Robert Andrews" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/5GP7-C585", "abstract": "No abstract. " }, { "name": "Winegarden, Howard Merlin", "degree": "Masters", "year": "1927", "title": "The Determination of Carbon Dioxide in Fermenting Mixtures. Co-Zymase: a Study of Purification Methods", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-12272004-144412", "creators": [ { "name": { "family": "Winegarden", "given": "Howard Merlin" }, "id": "Winegarden-Howard-Merlin", "display_name": "Winegarden, Howard Merlin" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/R7YV-A670", "abstract": "No abstract." }, { "name": "Baxter, Warren Phelps", "degree": "Masters", "year": "1926", "title": "The Interionic Attraction Theory of Ionized Solutes. Testing the Theory of Alcohol Solvents and by Solubility Experiments at Higher Temperature", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-11112004-144145", "creators": [ { "name": { "family": "Baxter", "given": "Warren Phelps" }, "id": "Baxter-Warren-Phelps", "display_name": "Baxter, Warren Phelps" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/3QH4-R578", "abstract": "No abstract.\r\n" }, { "name": "House, Harvey W.", "degree": "Masters", "year": "1926", "title": "The Activation of Sawdust Carbon for Decolorization", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-11112004-111421", "creators": [ { "name": { "family": "House", "given": "Harvey W." }, "id": "House-Harvey-W", "display_name": "House, Harvey W." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemeng" ], "doi": "10.7907/HYWP-K634", "abstract": "No abstract." }, { "name": "Alles, Gordon Albert", "degree": "Masters", "year": "1924", "title": "Experiments on the Chemical Behaviour of Insulin", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-04192004-135943", "creators": [ { "name": { "family": "Alles", "given": "Gordon Albert" }, "id": "Alles-Gordon-Albert", "display_name": "Alles, Gordon Albert" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/4VRT-8N60", "abstract": "No Abstract." }, { "name": "Raymond, Albert L.", "degree": "Masters", "year": "1923", "title": "The Crystal Structure of Hexamethylene-Tetramine", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechETD:etd-02252005-092152", "creators": [ { "name": { "family": "Raymond", "given": "Albert L." }, "id": "Raymond-Albert-L", "display_name": "Raymond, Albert L." } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/A6QY-FJ79", "abstract": "No abstract." }, { "name": "Kirschman, H. Darwin", "degree": "Masters", "year": "1919", "title": "The Vapor Pressure of Hydrogen Chloride and Hydrogen Bromide Above their Aqueous Solutions at 25", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:07262024-213658242", "creators": [ { "name": { "family": "Kirschman", "given": "H. Darwin" }, "id": "Kirschman-H-Darwin", "display_name": "Kirschman, H. Darwin" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/xym2-hn54", "abstract": "No abstract." }, { "name": "Hainsworth, William Richard", "degree": "Masters", "year": "1918", "title": "Equilibria Investigation of the Bucher Process for Nitrogen Fixation", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:07242024-153823595", "creators": [ { "name": { "family": "Hainsworth", "given": "William Richard" }, "id": "Hainsworth-William-Richard", "display_name": "Hainsworth, William Richard" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/a17y-hn74", "abstract": "No abstract." }, { "name": "Manning, Paul DeVries", "degree": "Masters", "year": "1917", "title": "The Equilibrium in a Process for the Production of Sodium Cyanide", "advisor": "Unknown, Unknown", "url": "https://resolver.caltech.edu/CaltechTHESIS:07052024-203247999", "creators": [ { "name": { "family": "Manning", "given": "Paul DeVries" }, "id": "Manning-Paul-DeVries", "display_name": "Manning, Paul DeVries" } ], "advisors": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "committee": [ { "name": { "family": "Unknown", "given": "Unknown" }, "display_name": "Unknown, Unknown" } ], "option_major": [ "chemistry" ], "doi": "10.7907/jjaf-m922", "abstract": "[Introduction]: The normally large demand for supplies of the various nitrogenous products of the industries has been greatly increased as a result of the war. The importation of nitrates to the United States from Chile would be stopped in case of a naval blockade. The problem of assuring an adequate supply of such materials is, therefore, a very pertinent one. This may best be solved by the improvement of the present commercial processes for the fixation of atmospheric nitrogen and by the development of new processes, not at present successful commercially. Apparently, the most\r\npromising known process of the latter class is based upon the formation of sodium cyanide by passing nitrogen gas over a mixture of sodium carbonate and carbon in the presence of a suitable\r\ncatalyzer at high temperatures." } ]